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Your search keyword '"Adriaan C.I.T.L. Tan"' showing total 8 results
Start Over Author "Adriaan C.I.T.L. Tan" Journal gastroenterology
8 results on '"Adriaan C.I.T.L. Tan"'

2. 570 – Early Endoscopic Retrograde Cholangiography with Biliary Sphincterotomy Or Conservative Treatment in Predicted Severe Acute Biliary Pancreatitis (APEC): A Multicenter Randomized Controlled Trial

Author

Marc G. Besselink, Casper H.J. van Eijck, Erwin-Jan M. van Geenen, Robert C. Verdonk, Niels G. Venneman, Nicole S. Erler, Olaf J. Bakker, Adriaan C.I.T.L. Tan, Janneke van Grinsven, Tessa E H Römkens, Hein G. Gooszen, Robert J.F. Laheij, Rogier de Ridder, Jeanin E. van Hooft, Ben J.M. Witteman, Marie-Paule Anten, Jeroen P. Jansen, Robin Timmer, Marco J. Bruno, Carola H.M. Ruigrok, G. Willemien Erkelens, Nora D L Hallensleben, Erik J. Schoon, Hjalmar C. van Santvoort, Marno C.M. Rijk, Thomas L. Bollen, Marcel Spanier, Foke van Delft, Rutger Quispel, Matthijs P. Schwartz, W van de Vrie, Nicolien J. Schepers, Willem J. Thijs, Hendrik M. van Dullemen, Marcel G. W. Dijkgraaf, René W M van der Hulst, Sjoerd D. Kuiken, Paul Fockens, Frank P. Vleggaar, and Frank J G M Kubben

Subjects
medicine.medical_specialty, Hepatology, business.industry, Gastroenterology, law.invention, Surgery, Conservative treatment, Randomized controlled trial, law, Biliary sphincterotomy, Endoscopic retrograde cholangiography, Medicine, Biliary pancreatitis, business
Published
2019

4. 773 Quality of Life After Stent Placement for Palliation of Common Bile Duct Obstruction: A Randomized Controlled Trial Comparing Plastic and Metal Stents

Author

Peter D. Siersema, Laurens A. van der Waaij, Meike M. Hirdes, Wim Laleman, Ben J.M. Witteman, Daisy Walter, Adriaan C.I.T.L. Tan, Menno A. Brink, Frans Peters, Niels G. Venneman, Frank Wolters, Frank P. Vleggaar, Petra G. Van Boeckel, Bas L. Weusten, Joyce Alderliesten, Alexander Bodelier, Jeroen M. Jansen, Marcel J M Groenen, Robert C.H. Scheffer, Ronald Breumelhof, Max Leenders, Jan Nicolai, and Gie Tan

Subjects
medicine.medical_specialty, Hepatology, business.industry, Common bile duct obstruction, Gastroenterology, Surgery, law.invention, Stent placement, Quality of life, Randomized controlled trial, law, medicine, Radiology, business
Published
2014

5. Sa1980 Barrett Associated MHC and FOXF1 Genotypes Also Increase Esophageal Carcinoma Risk in Caucasians: A Dutch Case-Control Study

Author

Polat Dura, Joost P.H. Drenth, Elke M. van Veen, Adriaan C.I.T.L. Tan, Hennie M.J. Roelofs, Theo Wobbes, Jody Salomon, Ben J.M. Witteman, Rene H. M. te Morsche, Wilbert H.M. Peters, and Jon O. Kristinsson

Subjects
Oncology, medicine.medical_specialty, Hepatology, biology, business.industry, Gastroenterology, Case-control study, medicine.disease, Major histocompatibility complex, Internal medicine, Genotype, medicine, Carcinoma, Cancer research, biology.protein, business
Published
2013

6. Su1843 High Enzyme Activity UGT1A1 or Low Activity Ugt1a8 and Ugt2b4 Genotypes Increase Esophageal Cancer Risk

Author

Polat Dura, Theo Wobbes, Joost P.H. Drenth, Wilbert H.M. Peters, Ben J.M. Witteman, Adriaan C.I.T.L. Tan, Jon O. Kristinsson, Rene H. M. te Morsche, Jody Salomon, and Hennie M.J. Roelofs

Subjects
chemistry.chemical_classification, Genetics, medicine.medical_specialty, UGT2B4, Hepatology, Bilirubin, Gastroenterology, Biology, Esophageal cancer, medicine.disease, Enzyme assay, chemistry.chemical_compound, Endocrinology, Enzyme, chemistry, Internal medicine, Genotype, medicine, biology.protein, Allele, Carcinogen
Abstract

Esophageal cancer (EC) has a globally increasing incidence with poor curative treatment options and survival rates. Environmental and dietary factors have crucial roles in esophageal carcinogenesis. Polymorphisms in the UGT genes, a superfamily of enzymes essential for the detoxification of carcinogens, may alter enzyme activity and subsequently may play a role in EC etiology. Rather than solely estab- lishing differences in genotype distribution, we investigated whether functional polymorphisms in UGT genes that can predict enzyme activity in vivo, may influence EC risk. A case-control study including 351 Caucasian EC patients and 592 Caucasian controls was conducted and polymorphisms in seven UGT genes were determined, using the polymerase chain reaction. On the basis of allelic in vitro enzyme activity measurements, genotypes were categorized according to their predicted in vivo enzyme activity into high, medium and low categories. Predicted enzyme activity groups were combined and compared between patients and controls. The UGT1A1 and UGT1A8 predicted high enzyme activity genotypes were significantly more (OR=1.62; 95% CI, 1.02-2.56) and less frequent (OR=0.36; 95% CI, 0.15-0.84) among patients with esophageal squamous cell carcinoma (ESCC), respectively. High (OR=0.42; 95% CI, 0.22-0.84) and medium (OR=0.25; 95% CI, 0.12-0.52) activity UGT2B4 genotypes were signifi - cantly less often present in ESCC patients. No association was detected between UGT genotypes and esophageal adenocar- cinoma (EAC) risk. Polymorphisms in UGT genes, resulting in altered enzyme activity genotypes, do not seem modifiers of EAC risk. However, the predicted high activity UGT1A1 genotype, associated with low serum levels of the antioxidant bilirubin, was associated with an increased ESCC risk. The UGT1A8 and UGT2B4 genotypes associated with decreased predicted enzyme activities, were significantly associated with an increased risk of ESCC, probably by a decreased detoxifi - cation of carcinogens.

Published
2012

8. S1043 Gender Differences in Upper Gastrointestinal Symptom Presentation

Author

Adriaan C.I.T.L. Tan, Robert J.F. Laheij, Martijn G.H. van Oijen, Jan B.M.J. Jansen, and Lieke A.S. van Kerkhoven

Subjects
medicine.medical_specialty, Hepatology, business.industry, Internal medicine, Gastroenterology, Medicine, Upper gastrointestinal, Presentation (obstetrics), business
Published
2008

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