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2. HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44+ Natural Killer Cells in Ulcerative Colitis

Author

Akar, Alaa, Flemming, Cornelius, Felix, Flomm, Flosbach, Markus, Jäger, Julia, Jeromin, Niklas, Jung, Johannes, Ohms, Mareike, Reinshagen, Konrad, Rische, Johann, Sagebiel, Adrian, Sandfort, Deborah, Steinert, Fenja, Tomuschat, Christian, Wesche, Jasmin, Shifteh Abedian, Abraham, Clara, Achkar, Jean-Paul, Ahmad, Tariq, Alberts, Rudi, Alizadeh, Behrooz, Amininejad, Leila, Ananthakrishnan, Ashwin N., Andersen, Vibeke, Anderson, Carl A., Andrews, Jane M., Annese, Vito, Aumais, Guy, Baidoo, Leonard, Baldassano, Robert N., Bampton, Peter A., Barclay, Murray, Barrett, Jeffrey C., Bethge, Johannes, Bewshea, Claire, Bis, Joshua C., Bitton, Alain, BK, Thelma, Boucher, Gabrielle, Brain, Oliver, Brand, Stephan, Brant, Steven R., Cheon, Jae Hee, Chew, Angela, Cho, Judy H., Cleynen, Isabelle, Cohain, Ariella, Cooney, Rachel, Croft, Anthony, Daly, Mark J., D'Amato, Mauro, Danese, Silvio, Daryani, Naser Ebrahim, Datta, Lisa Wu, Degenhardt, Frauke, Denapiene, Goda, Denson, Lee A., Devaney, Kathy L., Dewit, Olivier, D'Inca, Renata, Drummond, Hazel E., Dubinsky, Marla, Duerr, Richard H., Edwards, Cathryn, Ellinghaus, David, Ellul, Pierre, Esaki, Motohiro, Essers, Jonah, Ferguson, Lynnette R., Festen, Eleonora A., Fleshner, Philip, Florin, Tim, Franchimont, Denis, Franke, Andre, Fuyuno, Yuta, Gearry, Richard, Georges, Michel, Gieger, Christian, Glas, Jürgen, Goyette, Philippe, Green, Todd, Griffiths, Anne M., Guthery, Stephen L., Hakonarson, Hakon, Halfvarson, Jonas, Hanigan, Katherine, Haritunians, Talin, Hart, Ailsa, Hawkey, Chris, Hayward, Nicholas K., Hedl, Matija, Henderson, Paul, Hold, Georgina L., Hong, Myhunghee, Hu, Xinli, Huang, Hailiang, Hugot, Jean-Pierre, Hui, Ken Y., Imielinski, Marcin, Jazayeri, Omid, Jonaitis, Laimas, Jostins, Luke, Juyal, Garima, Chandra Juyal, Ramesh, Kalla, Rahul, Karlsen, Tom H., Kennedy, Nicholas A., Khan, Mohammed Azam, Kim, Won Ho, Kitazono, Takanari, Kiudelis, Gediminas, Kubo, Michiaki, Kugathasan, Subra, Kupcinskas, Limas, Lamb, Christopher A., de Lange, Katrina M., Latiano, Anna, Laukens, Debby, Lawrance, Ian C., Lee, James C., Lees, Charlie W., Leja, Marcis, Lewis, Nina, Van Limbergen, Johan, Lionetti, Paolo, Liu, Jimmy Z., Louis, Edouard, Luo, Yang, Mahy, Gillian, Malekzadeh, Masoud Mohammad, Malekzadeh, Reza, Mansfield, John, Marriott, Suzie, Massey, Dunecan, Mathew, Christopher G., Matsui, Toshiyuki, McGovern, Dermot P.B., van der Meulen, Andrea, Midha, Vandana, Milgrom, Raquel, Mirzaei, Samaneh, Mitrovic, Mitja, Montgomery, Grant W., Mowat, Craig, Müller, Christoph, Newman, William G., Ng, Aylwin, Ng, Siew C., Evelyn Ng, Sok Meng, Nikolaus, Susanna, Ning, Kaida, Nöthen, Markus, Oikonomou, Ioannis, Okou, David, Orchard, Timothy R., Palmieri, Orazio, Parkes, Miles, Phillips, Anne, Ponsioen, Cyriel Y., Potocnik, Urõs, Poustchi, Hossein, Prescott, Natalie J., Proctor, Deborah D., Radford-Smith, Graham, Rahier, Jean- Francois, Regueiro, Miguel, Reinisch, Walter, Rieder, Florian, Rioux, John D., Roberts, Rebecca, Rogler, Gerhard, Russell, Richard K., Sanderson, Jeremy D., Sans, Miquel, Satsangi, Jack, Schadt, Eric E., Scharl, Michael, Schembri, John, Schreiber, Stefan, Schumm, L. Philip, Scott, Regan, Seielstad, Mark, Shah, Tejas, Sharma, Yashoda, Silverberg, Mark S., Simmons, Alison, Simms, Lisa A., Singh, Abhey, Skieceviciene, Jurgita, van Sommeren, Suzanne, Song, Kyuyoung, Sood, Ajit, Spain, Sarah L., Steinhart, A. Hillary, Stempak, Joanne M., Stronati, Laura, Sung, Joseph J.Y., Targan, Stephan R., Taylor, Kirstin M., Theatre, Emilie, Torkvist, Leif, Torres, Esther A., Tremelling, Mark, Uhlig, Holm H., Umeno, Junji, Vahedi, Homayon, Vasiliauskas, Eric, Velde, Anje ter, Ventham, Nicholas T., Vermeire, Severine, Verspaget, Hein W., De Vos, Martine, Walters, Thomas, Wang, Kai, Wang, Ming-Hsi, Weersma, Rinse K., Wei, Zhi, Whiteman, David, Wijmenga, Cisca, Wilson, David C., Winkelmann, Juliane, Wong, Sunny H., Xavier, Ramnik J., Yamazaki, Keiko, Yang, Suk-Kyun, Ye, Byong Duk, Zeissig, Sebastian, Zhang, Bin, Zhang, Clarence K., Zhang, Hu, Zhang, Wei, Zhao, Hongyu, Zhao, Zhen Z., Baumdick, Martin E., Niehrs, Annika, Schwerk, Maria, Hinrichs, Ole, Jordan-Paiz, Ana, Padoan, Benedetta, Wegner, Lucy H.M., Schloer, Sebastian, Zecher, Britta F., Malsy, Jakob, Joshi, Vinita R., Illig, Christin, Schröder-Schwarz, Jennifer, Möller, Kimberly J., Martin, Maureen P., Yuki, Yuko, Ozawa, Mikki, Sauter, Jürgen, Schmidt, Alexander H., Perez, Daniel, Giannou, Anastasios D., Carrington, Mary, Davis, Randall S., Schumacher, Udo, Sauter, Guido, Huber, Samuel, Puelles, Victor G., Melling, Nathaniel, Altfeld, Marcus, and Bunders, Madeleine J.

Published
2023
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3. A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn’s Disease and Human Gut Microbiome Composition

Author

Li, Dalin, Achkar, Jean-Paul, Haritunians, Talin, Jacobs, Jonathan P, Hui, Ken Y, D'Amato, Mauro, Brand, Stephan, Radford-Smith, Graham, Halfvarson, Jonas, Niess, Jan-Hendrik, Kugathasan, Subra, Büning, Carsten, Schumm, L Philip, Klei, Lambertus, Ananthakrishnan, Ashwin, Aumais, Guy, Baidoo, Leonard, Dubinsky, Marla, Fiocchi, Claudio, Glas, Jürgen, Milgrom, Raquel, Proctor, Deborah D, Regueiro, Miguel, Simms, Lisa A, Stempak, Joanne M, Targan, Stephan R, Törkvist, Leif, Sharma, Yashoda, Devlin, Bernie, Borneman, James, Hakonarson, Hakon, Xavier, Ramnik J, Daly, Mark, Brant, Steven R, Rioux, John D, Silverberg, Mark S, Cho, Judy H, Braun, Jonathan, McGovern, Dermot PB, and Duerr, Richard H

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Nutrition and Dietetics, Genetics, Nutrition, Inflammatory Bowel Disease, Autoimmune Disease, Human Genome, Clinical Research, Digestive Diseases, Crohn's Disease, Aetiology, 2.1 Biological and endogenous factors, Oral and gastrointestinal, Alleles, Case-Control Studies, Cation Transport Proteins, Colitis, Ulcerative, Crohn Disease, Female, Gastrointestinal Microbiome, Genetic Pleiotropy, Genotype, Humans, Male, Mutation, Missense, Risk Factors, Inflammatory Bowel Diseases, Microbiota, Neurosciences, Paediatrics and Reproductive Medicine, Gastroenterology & Hepatology, Clinical sciences, Nutrition and dietetics
Abstract

Background & aimsGenome-wide association studies have identified 200 inflammatory bowel disease (IBD) loci, but the genetic architecture of Crohn's disease (CD) and ulcerative colitis remain incompletely defined. Here, we aimed to identify novel associations between IBD and functional genetic variants using the Illumina ExomeChip (San Diego, CA).MethodsGenotyping was performed in 10,523 IBD cases and 5726 non-IBD controls. There were 91,713 functional single-nucleotide polymorphism loci in coding regions analyzed. A novel identified association was replicated further in 2 independent cohorts. We further examined the association of the identified single-nucleotide polymorphism with microbiota from 338 mucosal lavage samples in the Mucosal Luminal Interface cohort measured using 16S sequencing.ResultsWe identified an association between CD and a missense variant encoding alanine or threonine at position 391 in the zinc transporter solute carrier family 39, member 8 protein (SLC39A8 alanine 391 threonine, rs13107325) and replicated the association with CD in 2 replication cohorts (combined meta-analysis P = 5.55 × 10(-13)). This variant has been associated previously with distinct phenotypes including obesity, lipid levels, blood pressure, and schizophrenia. We subsequently determined that the CD risk allele was associated with altered colonic mucosal microbiome composition in both healthy controls (P = .009) and CD cases (P = .0009). Moreover, microbes depleted in healthy carriers strongly overlap with those reduced in CD patients (P = 9.24 × 10(-16)) and overweight individuals (P = 6.73 × 10(-16)).ConclusionsOur results suggest that an SLC39A8-dependent shift in the gut microbiome could explain its pleiotropic effects on multiple complex diseases including CD.

Published
2016

5. Association Between Variants of PRDM1 and NDP52 and Crohn's Disease, Based on Exome Sequencing and Functional Studies

Author

Ellinghaus, David, Zhang, Hu, Zeissig, Sebastian, Lipinski, Simone, Till, Andreas, Jiang, Tao, Stade, Björn, Bromberg, Yana, Ellinghaus, Eva, Keller, Andreas, Rivas, Manuel A, Skieceviciene, Jurgita, Doncheva, Nadezhda T, Liu, Xiao, Liu, Qing, Jiang, Fuman, Forster, Michael, Mayr, Gabriele, Albrecht, Mario, Häsler, Robert, Boehm, Bernhard O, Goodall, Jane, Berzuini, Carlo R, Lee, James, Andersen, Vibeke, Vogel, Ulla, Kupcinskas, Limas, Kayser, Manfred, Krawczak, Michael, Nikolaus, Susanna, Weersma, Rinse K, Ponsioen, Cyriel Y, Sans, Miquel, Wijmenga, Cisca, Strachan, David P, McArdle, Wendy L, Vermeire, Séverine, Rutgeerts, Paul, Sanderson, Jeremy D, Mathew, Christopher G, Vatn, Morten H, Wang, Jun, Nöthen, Markus M, Duerr, Richard H, Büning, Carsten, Brand, Stephan, Glas, Jürgen, Winkelmann, Juliane, Illig, Thomas, Latiano, Anna, Annese, Vito, Halfvarson, Jonas, D'Amato, Mauro, Daly, Mark J, Nothnagel, Michael, Karlsen, Tom H, Subramani, Suresh, Rosenstiel, Philip, Schreiber, Stefan, Parkes, Miles, and Franke, Andre

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Nutrition and Dietetics, Biotechnology, Genetics, Inflammatory Bowel Disease, Autoimmune Disease, Human Genome, Clinical Research, Digestive Diseases, Crohn's Disease, Aetiology, 2.1 Biological and endogenous factors, Oral and gastrointestinal, Inflammatory and immune system, Adolescent, Adult, Case-Control Studies, Colitis, Ulcerative, Crohn Disease, Exome, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Male, Mutation, Missense, Nuclear Proteins, Polymorphism, Single Nucleotide, Positive Regulatory Domain I-Binding Factor 1, Quantitative Trait Loci, Repressor Proteins, Young Adult, Whole-Exome Sequencing, Complex Disease, CD, Crohn’s disease, GWAS, IBD, IFN, NF-κB, PBL, PBMC, SNP, SNV, TLR, Toll-like receptor, UC, WT, eQTL, expression quantitative trait locus, genome-wide association studies, inflammatory bowel disease, interferon, nuclear factor κB, peripheral blood lymphocyte, peripheral blood mononuclear cell, qRT-PCR, quantitative reverse-transcription polymerase chain reaction, single nucleotide polymorphism, single nucleotide variant, ulcerative colitis, wild-type, Neurosciences, Paediatrics and Reproductive Medicine, Gastroenterology & Hepatology, Clinical sciences, Nutrition and dietetics
Abstract

Background & aimsGenome-wide association studies (GWAS) have identified 140 Crohn's disease (CD) susceptibility loci. For most loci, the variants that cause disease are not known and the genes affected by these variants have not been identified. We aimed to identify variants that cause CD through detailed sequencing, genetic association, expression, and functional studies.MethodsWe sequenced whole exomes of 42 unrelated subjects with CD and 5 healthy subjects (controls) and then filtered single nucleotide variants by incorporating association results from meta-analyses of CD GWAS and in silico mutation effect prediction algorithms. We then genotyped 9348 subjects with CD, 2868 subjects with ulcerative colitis, and 14,567 control subjects and associated variants analyzed in functional studies using materials from subjects and controls and in vitro model systems.ResultsWe identified rare missense mutations in PR domain-containing 1 (PRDM1) and associated these with CD. These mutations increased proliferation of T cells and secretion of cytokines on activation and increased expression of the adhesion molecule L-selectin. A common CD risk allele, identified in GWAS, correlated with reduced expression of PRDM1 in ileal biopsy specimens and peripheral blood mononuclear cells (combined P = 1.6 × 10(-8)). We identified an association between CD and a common missense variant, Val248Ala, in nuclear domain 10 protein 52 (NDP52) (P = 4.83 × 10(-9)). We found that this variant impairs the regulatory functions of NDP52 to inhibit nuclear factor κB activation of genes that regulate inflammation and affect the stability of proteins in Toll-like receptor pathways.ConclusionsWe have extended the results of GWAS and provide evidence that variants in PRDM1 and NDP52 determine susceptibility to CD. PRDM1 maps adjacent to a CD interval identified in GWAS and encodes a transcription factor expressed by T and B cells. NDP52 is an adaptor protein that functions in selective autophagy of intracellular bacteria and signaling molecules, supporting the role of autophagy in the pathogenesis of CD.

Published
2013

7. Tu1545: TRANS-CONTINENTAL ANALYSIS OF OVER 2,000 INFLAMMATORY BOWEL DISEASE PATIENTS IMPLICATES GEOGRAPHY, DISEASE TYPE, AND EXPOSURE TO IMMUNOSUPPRESSION AS DRIVERS OF SARS-COV-2 SEROPREVALENCE

Author

Wong, Serre-Yu, primary, Helmus, Drew, additional, Marlow, Luke, additional, Pazos, Vicky Martinez, additional, Brann, Stephanie, additional, Wellens, Judith, additional, Kedia, Saurabh, additional, Mak, Joyce W., additional, Bergemalm, Daniel, additional, Argollo, Marjorie C., additional, Zaltman, Cyrla, additional, Steinwurz, Flavio, additional, Allez, Matthieu, additional, Abreu, Maria T., additional, Rubin, David T., additional, Halfvarson, Jonas, additional, Lindsay, James O., additional, Dutta, Usha, additional, Silverberg, Mark S., additional, Ng, Siew C., additional, Ahuja, Vineet, additional, Watanabe, Kenji, additional, Vermeire, Severine, additional, Colombel, Jean Frederic, additional, and Satsangi, Jack J., additional

Published
2022
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8. Sa1583: SERUM PROTEOMIC MARKERS THAT PREDICT FUTURE CROHN'S DISEASE DEVELOPMENT ARE ASSOCIATED WITH GUT BARRIER FUNCTION, SUBCLINICAL GUT INFLAMMATION AND IMMUNE RESPONSE TO BACTERIAL ANTIGENS

Author

Leibovitzh, Haim, primary, Garay, Juan Antonio Raygoza, additional, Xue, Mingyue, additional, Neustaeter, Anna, additional, Espin-Garcia, Osvaldo, additional, Huynh, Hien Q., additional, Griffiths, Anne M., additional, Turner, Dan, additional, Madsen, Karen, additional, Steinhart, A. Hillary, additional, Princen, Fred, additional, Mack, David R., additional, Jacobson, Kevan, additional, Ropeleski, Mark, additional, Cino, Maria, additional, Aumais, Guy L., additional, Panaccione, Remo, additional, Halfvarson, Jonas, additional, Xu, Wei, additional, Lee, Sun-Ho, additional, Turpin, Williams, additional, and Croitoru, Kenneth, additional

Published
2022
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11. Challenges and Opportunities in IBD Clinical Trial Design

Author

Dubinsky, Marla C., primary, Collins, Rory, additional, Abreu, Maria T., additional, Dubinsky, Marla C., additional, Jairath, Vipul, additional, Lewis, James D., additional, Lindsay, James, additional, Merad, Miriam, additional, Ng, Siew, additional, Panaccione, Remo, additional, Panes, Julian, additional, Sands, Bruce, additional, Siegal, Corey A., additional, Singh, Siddarth, additional, Vermeire, Severine, additional, Ahuja, Vineet, additional, Allez, Matthieu, additional, Ananthakrishnan, Ashwin, additional, Bemelman, Willem, additional, Braun, Jonathan, additional, Colombel, Jean-Frederic, additional, Danese, Silvio, additional, D’Haens, Geert, additional, D’Hoore, André, additional, Dignass, Axel, additional, Dotan, Iris, additional, Gassul, Miguel Angel, additional, Griffiths, Anne, additional, Halfvarson, Jonas, additional, Hanauer, Stephen, additional, Kotze, Paulo, additional, Koutroubakis, Ioannis, additional, Loftus, Edward, additional, Louis, Edouard, additional, Magro, Fernando, additional, Mantzaris, Gerassimos, additional, Mary, Jean-Yves, additional, McGovern, Dermot, additional, Munkholm, Pia, additional, O’Morain, Colm, additional, Panis, Yves, additional, Peyrin-Biroulet, Laurent, additional, Prantera, Cosimo, additional, Ran, Zhihua, additional, Siegmund, Britta, additional, Silverberg, Mark, additional, Stange, Eduard, additional, Targan, Stephan, additional, Tysk, Curt, additional, Travis, Simon, additional, Vatn, Morton, additional, Yamamoto-Furusho, Yesus, additional, Aarts, Janske, additional, Abhyankar, Brihad, additional, Ahmad, Harris, additional, Aranda, Richard, additional, Arora, Vipin, additional, Benjacoub, Jalil, additional, Berg, Sofie, additional, Besuyen, Robin, additional, Bojic, Daniela, additional, Carriero, Valerio, additional, Cataldi, Fabio, additional, D’Agay, Laurence, additional, Delgado-Aros, Silvia, additional, Giannasca, Paul, additional, Goyal, Kavitha, additional, Greinwald, Roland, additional, Gropper, Savion, additional, Kageyama, Shunsuke, additional, Laoun, Raphaël, additional, Levesque, Barrett, additional, Lissoos, Trevor, additional, Modesto, Irene, additional, Mohrbacher, Ralf, additional, Mueller, Ralph, additional, Naegeli, April, additional, Naik, Snehal, additional, Nguyen, Deanne, additional, Niezychowski, Wojciech, additional, O’Brien, Caitriona, additional, Odnoletkova, Irina, additional, Oortwijn, Alessandra, additional, Park, Kun K.T., additional, Radziszewski, Waldemar, additional, Salese, Leonardo, additional, Spleiss, Johannes, additional, Stancati, Andrea, additional, Tatro, Amanda, additional, Thompson, Jennifer, additional, Hofmann, Robert, additional, Zambrano, Javier, additional, Zhou, Wen, additional, and Zigmont, Ellen, additional

Published
2021
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12. Serologic Response to Messenger RNA Coronavirus Disease 2019 Vaccines in Inflammatory Bowel Disease Patients Receiving Biologic Therapies

Author

Wong, Serre-Yu, primary, Dixon, Rebekah, additional, Martinez Pazos, Vicky, additional, Gnjatic, Sacha, additional, Colombel, Jean-Frederic, additional, Cadwell, Ken, additional, Gold, Stephanie, additional, Helmus, Drew, additional, Neil, Jessica Anne, additional, Sota, Stela, additional, Jang, Kyung Ku, additional, Ching, Krystal, additional, Venzon, Mericien, additional, Yao, Xiaomin, additional, Bernard, Lucie, additional, Chen, Xin, additional, Navalurkar, Reema, additional, Mendiolaza, Michelle, additional, Reyes-Mercedes, Pamela, additional, Nunez, Sara, additional, Stanley, Stephanie, additional, Jimenez, Darwin, additional, Tankelevich, Michael, additional, Phillipe, Brianne, additional, Ramos, Julio, additional, Tuballes, Kevin, additional, Barcessat, Vanessa, additional, Herrera, Natalia, additional, Satsangi, Jack, additional, Watanabe, Kenji, additional, Vermeire, Séverine, additional, Steinwurz, Flavio, additional, Silverberg, Mark, additional, Rubin, David T., additional, Roda, Giulia, additional, Reinisch, Walter, additional, Ng, Siew Chien, additional, Lindsay, James, additional, Halfvarson, Jonas, additional, Allez, Matthieu, additional, Ahuja, Vineet, additional, and Abreu, Maria, additional

Published
2021
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13. Selecting End Points for Disease-Modification Trials in Inflammatory Bowel Disease: the SPIRIT Consensus From the IOIBD

Author

Le Berre, Catherine, primary, Peyrin-Biroulet, Laurent, additional, Sandborn, William J., additional, Colombel, Jean-Frédéric, additional, Rubin, David, additional, Chowers, Yehuda, additional, Reinisch, Walter, additional, Schreiber, Stefan, additional, Allez, Matthieu, additional, D’Haens, Geert, additional, Ghosh, Subrata, additional, Koutroubakis, Ioannis E., additional, Gibson, Peter, additional, Halfvarson, Jonas, additional, Hart, Ailsa, additional, Kaser, Arthur, additional, Munkholm, Pia, additional, Kruis, Wolfgang, additional, Vermeire, Severine, additional, Loftus, Edward V., additional, Lukas, Milan, additional, Mantzaris, Gerassimos J., additional, O’Morain, Colm, additional, Panes, Julian, additional, Rogler, Gerhard, additional, Spinelli, Antonino, additional, Sands, Bruce E., additional, Ananthakrishnan, Aswhin N., additional, Ng, Siew C., additional, Sachar, David, additional, Travis, Simon, additional, Steinwurz, Flavio, additional, Turner, Dan, additional, Dulai, Parambir S., additional, Jairath, Vipul, additional, Dotan, Iris, additional, Abreu, Maria, additional, Panaccione, Remo, additional, and Danese, Silvio, additional

Published
2021
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16. Su1759 IDENTIFICATION AND VALIDATION OF A LIPIDOMIC SIGNATURE AS A NOVEL DIAGNOSTIC BIOMARKER OF PEDIATRIC INFLAMMATORY BOWEL DISEASE

Author

Salihovic, Samira, Nyström, Niklas, Mathisen, Charlotte B., Andersen, Svend, Olbj⊘rn, Christine, Perminow, G⊘ri, Opheim, Randi, Detlie, Trond Espen, Huppertz-Hauss, Gert, Bazov, Igor, Kruse, Robert, Lindqvist, Carl Mårten, Hedin, Charlotte R., Carlson, Marie, Ohman, Lena, Magnusson, Maria K., Keita, Åsa V., Söderholm, Johan D., D'Amato, Mauro, Oresic, Matej, Repsilber, Dirk, Hyötyläinen, Tuulia, Hoivik, Marte L., and Halfvarson, Jonas

Published
2023
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17. Su1757 A NOVEL DIAGNOSTIC SERUM PROTEIN SIGNATURE FOR PEDIATRIC INFLAMMATORY BOWEL DISEASE: A DISCOVERY AND VALIDATION STUDY IN TWO INDEPENDENT INCEPTION COHORTS

Author

Mathisen, Charlotte B., Bazov, Igor, Nyström, Niklas, Andersen, Svend, Olbj⊘rn, Christine, Perminow, G⊘ri, Kristensen, Vendel, Opheim, Randi, Ricanek, Petr, D'Amato, Mauro, Carlson, Marie, Hedin, Charlotte R., Keita, Åsa V., Kruse, Robert, Lindqvist, Carl Mårten, Magnusson, Maria K., Salihovic, Samira, Söderholm, Johan D., Ohman, Lena, Repsilber, Dirk, H⊘ivik, Marte Lie, and Halfvarson, Jonas

Published
2023
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18. Su1758 A NOVEL SERUM PROTEIN SIGNATURE AS BIOMARKER FOR INFLAMMATORY BOWEL DISEASE: A DIAGNOSTIC PERFORMANCE AND PREDICTION MODELLING STUDY USING DATA FROM TWO INDEPENDENT INCEPTION COHORTS

Author

Bazov, Igor, Kruse, Robert, Daniel, Bergemalm, Eriksson, Carl, Hedin, Charlotte R., Carlson, Marie, van Nieuwenhoven, Michiel, Keita, Åsa V., Magnusson, Maria K., Almer, Sven, Strid, Hans, Mathisen, Charlotte B., Bengtson, May-Bente, Aaabrekke, Tone Bergene, Medhus, Asle W., Detlie, Trond Espen, Frigstad, Svein Oskar, Huppertz-Hauss, Gert, Opheim, Randi, Ricanek, Petr, Kristensen, Vendel, Salihovic, Samira, D'Amato, Mauro, Ohman, Lena, Söderholm, Johan D., Lindqvist, Carl Mårten, Repsilber, Dirk, H⊘ivik, Marte Lie, and Halfvarson, Jonas

Published
2023
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23. Deep Remission at 1 Year Prevents Progression of Early Crohn’s Disease

Author

Ungaro, Ryan C., primary, Yzet, Clara, additional, Bossuyt, Peter, additional, Baert, Filip J., additional, Vanasek, Thomas, additional, D’Haens, Geert R., additional, Joustra, Vincent Wilhelmus, additional, Panaccione, Remo, additional, Novacek, Gottfried, additional, Reinisch, Walter, additional, Armuzzi, Alessandro, additional, Golovchenko, Oleksandr, additional, Prymak, Olga, additional, Goldis, Adrian, additional, Travis, Simon P., additional, Hébuterne, Xavier, additional, Ferrante, Marc, additional, Rogler, Gerhard, additional, Fumery, Mathurin, additional, Danese, Silvio, additional, Rydzewska, Grazyna, additional, Pariente, Benjamin, additional, Hertervig, Erik, additional, Stanciu, Carol, additional, Serrero, Melanie, additional, Diculescu, Mircea, additional, Peyrin-Biroulet, Laurent, additional, Laharie, David, additional, Wright, John P., additional, Gomollón, Fernando, additional, Gubonina, Irina, additional, Schreiber, Stefan, additional, Motoya, Satoshi, additional, Hellström, Per M., additional, Halfvarson, Jonas, additional, Butler, James W., additional, Petersson, Joel, additional, Petralia, Francesca, additional, and Colombel, Jean-Frederic, additional

Published
2020
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24. Management of Patients With Crohn’s Disease and Ulcerative Colitis During the Coronavirus Disease-2019 Pandemic: Results of an International Meeting

Author

Rubin, David T., primary, Abreu, Maria T., additional, Rai, Victoria, additional, Siegel, Corey A., additional, Ahuja, Vineet, additional, Allez, Matthieu, additional, Ananthakrishnan, Ashwin N., additional, Bernstein, Charles N., additional, Braun, Jonathan G., additional, Chowers, Yehuda, additional, Colombel, Jean-Frederic, additional, Danese, Silvio, additional, D'Haens, Geert, additional, D'Hoore, Andre, additional, Dignass, Axel, additional, Dotan, Iris, additional, Dubinsky, Marla C., additional, Ekbom, Anders, additional, Fleshner, Phillip R., additional, Gassull, Miquel A., additional, Gearry, Richard B., additional, Ghosh, Subrata, additional, Griffiths, Anne M., additional, Halfvarson, Jonas, additional, Hanauer, Stephen B., additional, Harpaz, Noam, additional, Hart, Ailsa, additional, Kamm, Michael A., additional, Kaplan, Gil G., additional, Koutroubakis, Ioannis, additional, Lakatos, Peter L., additional, Levine, Arie, additional, Lewis, James D., additional, Lindsay, James O., additional, Loftus, Edward V., additional, Louis, Edouard, additional, Lukas, Milan, additional, Magro, Fernando, additional, Mahadevan, Uma, additional, Mantzaris, Gerasimos J., additional, McGovern, Dermot P., additional, Moum, Bjørn A., additional, Munkholm, Pia, additional, Neurath, Markus F., additional, Ng, Siew C., additional, O'Morain, Colm, additional, Panaccione, Remo, additional, Panes, Julian, additional, Peyrin-Biroulet, Laurent, additional, Prantera, Cosimo, additional, Ran, Zhihua, additional, Reinisch, Walter, additional, Remzi, Feza H., additional, Sachar, David B., additional, Sandborn, William J., additional, Sartor, R. Balfour, additional, Schölmerich, Jürgen, additional, Schreiber, Stefan, additional, Siegmund, Britta, additional, Silverberg, Mark S., additional, Söderholm, Johan D., additional, Stange, Eduard F., additional, Steinwurz, Flavio, additional, Turner, Dan, additional, Vatn, Morten H., additional, Vermeire, Severine, additional, Brenner, Erica J., additional, Christensen, Britt, additional, D'Amico, Ferdinando, additional, Griffiths, Chris M., additional, Higgins, Peter D., additional, Kappelman, Michael D., additional, Lees, Charlie, additional, Regueiro, Miguel D., additional, Rosh, Joel R., additional, and Ungaro, Ryan, additional

Published
2020
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25. 398 THE GEM PROJECT: IDENTIFICATION OF A SERUM PROTEOMIC SIGNATURE ASSOCIATED WITH RISK OF FUTURE CROHN'S DISEASE ONSET IN A COHORT OF HEALTHY AT-RISK INDIVIDUALS

Author

Garay, Juan Antonio Raygoza, primary, Turpin, Williams, additional, Smith, Michelle I., additional, Goethel, Ashleigh, additional, Huynh, Hien Q., additional, Griffiths, Anne M., additional, Turner, Dan, additional, Steinhart, A. Hillary, additional, Seidman, Ernest G., additional, Mack, David R., additional, Jacobson, Kevan, additional, Ropeleski, Mark, additional, Cino, Maria, additional, Aumais, Guy L., additional, Panaccione, Remo, additional, Deslandres, Colette, additional, Wrobel, Iwona, additional, Halfvarson, Jonas, additional, and Croitoru, Kenneth, additional

Published
2020
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26. Su1912 CDEIS SCORE OF 2 IS OPTIMAL CUT-OFF ASSOCIATED WITH LOWER RISK OF DISEASE PROGRESSION IN EARLY CROHN'S DISEASE: DATA FROM THE CALM STUDY

Author

Ungaro, Ryan C., primary, Jordan, Robyn, additional, Yzet, Clara, additional, Bossuyt, Peter, additional, Baert, Filip J., additional, Vanasek, Tomas, additional, D'Haens, Geert R., additional, Joustra, Vincent W., additional, Panaccione, Remo, additional, Novacek, Gottfried, additional, Reinisch, Walter, additional, Armuzzi, Alessandro, additional, Golovchenko, Oleksandr, additional, Olga, Prymak, additional, Goldis, Adrian, additional, Travis, Simon P., additional, Hebuterne, Xavier, additional, Ferrante, Marc, additional, Rogler, Gerhard, additional, Fumery, Mathurin, additional, Danese, Silvio, additional, Rydzewska-Wyszkowska, Grazyna, additional, Pariente, Benjamin, additional, Hertervig, Erik, additional, Stanciu, Carol, additional, Serrero, Mélanie, additional, Diculescu, Mircea, additional, Peyrin-Biroulet, Laurent, additional, Laharie, David, additional, Wright, John P, additional, Gomollon, Fernando, additional, Gubonina, Irina, additional, Schreiber, Stefan, additional, Motoya, Satoshi, additional, Hellström, Per M., additional, Halfvarson, Jonas, additional, and Colombel, Jean Frederic, additional

Published
2020
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27. Mo1886 REAL-WORLD EFFECTIVENESS OF VEDOLIZUMAB IN CROHN'S DISEASE: WEEK 52 RESULTS FROM THE SWEDISH MULTI-CENTER, PROSPECTIVE, OBSERVATIONAL SVEAH CD STUDY

Author

Eriksson, Carl, primary, Rundquist, Sara, additional, Lykiardopoulos, Byron, additional, Udumyan, Ruzan, additional, Karlén, Per, additional, Grip, Olof, additional, Soderman, Charlotte, additional, Almer, Sven, additional, Hertervig, Erik, additional, Gunnarsson, Jenny, additional, Malmgren, Carolina, additional, Delin, Jenny, additional, Strid, Hans, additional, Sjöberg, Mats, additional, Öberg, David, additional, Daniel, Bergemalm, additional, Hjortswang, Henrik, additional, and Halfvarson, Jonas, additional

Published
2020
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28. Mo1115 WHOLE-BLOOD EXPRESSION PROFILES IN INFLAMMATORY BOWEL DISEASE REVEAL TRANSCRIPTION FACTOR INVOLVEMENT

Author

Nowak, Jan, primary, Adams, Alex, additional, Kalla, Rahul, additional, Bergemalm, Daniel, additional, Vatn, Simen, additional, Kennedy, Nicholas A., additional, Ricanek, Petr, additional, Lindström, Jonas, additional, Ocklind, Anette, additional, Hjelm, Fredrik, additional, Ventham, Nicholas T., additional, Ho, Gwo-tzer, additional, Repsilber, Dirk, additional, Söderholm, Johan, additional, Pierik, Marie, additional, D'Amato, Mauro, additional, Gomollon, Fernando, additional, Olbjørn, Christine, additional, Jahnsen, Jorgen, additional, Gut, Ivo, additional, Vatn, Morten H., additional, Halfvarson, Jonas, additional, and Satsangi, Jack, additional

Published
2020
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30. Mo1764 – Serum N-Glycomic Biomarkers Predict Treatment Escalation in Inflammatory Bowel Disease

Author

Shubhakar, Archana, primary, Jansen, Bas, additional, Adams, Alex, additional, Reiding, Karli, additional, Ventham, Nicholas T., additional, Daniel, Bergemalm, additional, Urbanowicz, Paulina, additional, Gardner, Richard, additional, Halfvarson, Jonas, additional, Satsangi, Jack, additional, Fernandes, D.L., additional, Wuhrer, Manfred, additional, and Spencer, Daniel I., additional

Published
2019
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31. Sa1812 – Endoscopic and Deep Remission At 1 Year Prevents Disease Progression in Early Crohn's Disease: Long-Term Data from Calm

Author

Ungaro, Ryan C., primary, Yzet, Clara, additional, Bossuyt, Peter, additional, Baert, Filip J., additional, Vanasek, Tomas, additional, D'Haens, Geert R., additional, Joustra, Vincent W., additional, Panaccione, Remo, additional, Novacek, Gottfried, additional, Armuzzi, Alessandro, additional, Golovchenko, Oleksandr, additional, Olga, Prymak, additional, Goldis, Adrian, additional, Travis, Simon P., additional, Hebuterne, Xavier, additional, Ferrante, Marc, additional, Rogler, Gerhard, additional, Fumery, Mathurin, additional, Danese, Silvio, additional, Rydzewska, Grazyna, additional, Pariente, Benjamin, additional, Hertervig, Erik, additional, Stanciu, Carol, additional, Grimaud, Jean-charles, additional, Diculescu, Mircea, additional, Peyrin-Biroulet, Laurent, additional, Laharie, David, additional, Wright, John P, additional, Gomollon, Fernando, additional, Gubonina, Irina, additional, Schreiber, Stefan, additional, Motoya, Satoshi, additional, Hellström, Per M., additional, Halfvarson, Jonas, additional, and Colombel, Jean Frederic, additional

Published
2019
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33. Mo1894 - Clinical Effectiveness of Vedolizumab: Interim Analysis of the Swedish Observational Study on Vedolizumab Assessing Effectiveness and Healthcare Resource Utilization in Patients with Ulcerative Colitis (Sveah UC)

Author

Eriksson, Carl, primary, Rundquist, Sara, additional, Lykiardopoulos, Vyron, additional, Karlén, Per, additional, Grip, Olof, additional, Soderman, Charlotte, additional, Almer, Sven, additional, Hertervig, Erik, additional, Gunnarsson, Jenny, additional, Malmgren, Carolina, additional, Delin, Jenny, additional, Strid, Hans, additional, Sjöberg, Mats, additional, Öberg, David, additional, Bergemalm, Daniel, additional, Udumyan, Ruzan, additional, Hjortswang, Henrik, additional, and Halfvarson, Jonas, additional

Published
2018
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36. Mo1892 - Clinical Effectiveness of Vedolizumab: Interim Analysis of the Swedish Observational Study on Vedolizumab Assessing Effectiveness and Healthcare Resource Utilization in Patients with Crohn's Disease (Sveah CD)

Author

Eriksson, Carl, primary, Rundquist, Sara, additional, Lykiardopoulos, Vyron, additional, Karlén, Per, additional, Grip, Olof, additional, Soderman, Charlotte, additional, Almer, Sven, additional, Hertervig, Erik, additional, Gunnarsson, Jenny, additional, Malmgren, Carolina, additional, Delin, Jenny, additional, Strid, Hans, additional, Sjöberg, Mats, additional, Öberg, David, additional, Bergemalm, Daniel, additional, Udumyan, Ruzan, additional, Hjortswang, Henrik, additional, and Halfvarson, Jonas, additional

Published
2018
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37. Epigenetic Alterations at Diagnosis Predict Susceptibility, Prognosis and Treatment Escalation in Inflammatory Bowel Disease and IBD Character

Author

Kalla, Rahul, primary, Adams, Alex, additional, Vatn, Simen, additional, Bonfiglio, Ferdinando, additional, Nimmo, Elaine, additional, Kennedy, Nicholas, additional, Ventham, Nicholas, additional, Consortium, IBD Character, additional, Vatn, Morten H., additional, Ricanek, Petr, additional, Bergemalm, Daniel, additional, Halfvarson, Jonas, additional, Söderholm, Johan, additional, Pierik, Marie, additional, Törkvist, Leif, additional, Gomollon, Fernando, additional, Gut, Ivo, additional, Jahnsen, Jorgen, additional, and Satsangi, Jack, additional

Published
2017
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38. Su1784 PEA Immunoassay Technology Identifies Novel Serum Biomarkers That Can Diagnose and Classify Inflammatory Bowel Diseases: IBD Character Consortium

Author

Kalla, Rahul, primary, Ocklind, Anette, additional, Petrén, Cecilia, additional, Nordberg, Niklas, additional, kennedy, Nicholas, additional, Ventham, Nicholas, additional, Pettersson, Erik, additional, Bergemalm, Daniel, additional, Lindström, Jonas, additional, Nimmo, Elaine, additional, Drummond, Hazel, additional, Vatn, Simen, additional, Hjortswang, Henrik, additional, Ricanek, Petr, additional, Dahl, Fredrik, additional, Wilson, David, additional, Gomollon, Fernando, additional, Jahnsen, Jorgen, additional, Pierik, Marie, additional, Söderholm, Johan, additional, Vatn, Morten H., additional, Halfvarson, Jonas, additional, Consortium, IBD Character, additional, and Satsangi, Jack, additional

Published
2016
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39. Tu1962 Looking Beyond Symptoms and Disease Activity to Define Disease Severity in Inflammatory Bowel Disease: Results of an IOIBD Specialist Panel

Author

Siegel, Corey A., primary, Whitman, Cynthia B., additional, Spiegel, Brennan, additional, Feagan, Brian G., additional, Sands, Bruce E., additional, Loftus, Edward V., additional, Panaccione, Remo, additional, D'Haens, Geert R., additional, Bernstein, Charles N., additional, Gearry, Richard B., additional, Ng, Siew C., additional, Mantzaris, Gerassimos J., additional, Sartor, R. Balfour, additional, Silverberg, Mark S., additional, Riddell, Robert, additional, Koutroubakis, Ioannis, additional, O'Morain, Colm A., additional, Lakatos, Peter L., additional, McGovern, Dermot, additional, Halfvarson, Jonas, additional, Reinisch, Walter, additional, Rogler, Gerhard, additional, Kruis, Wolfgang, additional, Tysk, Curt, additional, Schreiber, Stefan, additional, Danese, Silvio, additional, Sandborn, William, additional, Griffiths, Anne M., additional, Moum, Bjorn, additional, Gasche, Christoph, additional, Pallone, Francesco, additional, Travis, Simon, additional, Panés, Julian, additional, Colombel, Jean-Frederic, additional, Hanauer, Stephen B., additional, and Peyrin-Biroulet, Laurent, additional

Published
2016
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40. Tu1368 Vedolizumab in Inflammatory Bowel Disease, the First Experience From the Swedish IBD Registry (SWIBREG)

Author

Eriksson, Carl, primary, Almer, Sven, additional, Björk, Jan A., additional, Eberhardson, Michael, additional, Eriksson, Anders, additional, Grip, Olof, additional, Hertervig, Erik, additional, Höög, Charlotte, additional, Jäghult, Susanna, additional, Karlén, Per, additional, Ludvigsson, Jonas, additional, Marsal, Jan, additional, Sjöberg, Daniel, additional, Stjernman, Henrik, additional, Strid, Hans, additional, Thörn, Mari, additional, Vigren, Lina, additional, Hjortswang, Henrik, additional, and Halfvarson, Jonas, additional

Published
2015
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41. Mo1802 Intestinal Dysbiosis in Collagenous Colitis

Author

Carstens, Adam, primary, Dicksved, Johan, additional, Nelson, Ronald, additional, Andreasson, Anna, additional, Bohr, Johan, additional, Tysk, Curt, additional, Agreus, Lars, additional, Engstrand, Lars, additional, and Halfvarson, Jonas, additional

Published
2015
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42. Su1201 Proximity Extension Assay Technology Identifies Novel Serum Biomarkers for Predicting Inflammatory Bowel Disease: IBD Character Consortium

Author

Kalla, Rahul, primary, Kennedy, Nicholas A., additional, Hjelm, Fredrik N., additional, Modig, Eddie, additional, Sundell, Mikael, additional, Söderholm, Johan, additional, Andreassen, Bettina K., additional, Bergemalm, Daniel, additional, Ventham, Nicholas T., additional, Hjortswang, Henrik, additional, Ricanek, Petr, additional, Vatn, Morten H., additional, Halfvarson, Jonas, additional, Gullberg, Mats, additional, Character, IBD, additional, and Satsangi, Jack, additional

Published
2015
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43. Su1316 Unchanged Surgery and Hospitalization Rates in an East-West European Inception Cohort Despite Differences in Use of Biologicals - 3-Year Follow-Up of the ECCO-EpiCom Cohort

Author

Burisch, Johan, primary, Kaimakliotis, John, additional, Duricova, Dana., additional, Kievit, Linda, additional, Dahlerup, Jens F., additional, Salupere, Riina, additional, Nielsen, Kári R., additional, Manninen, Pia, additional, Tsianos, Epameinondas V., additional, Vegh, Zsuzsanna, additional, Odes, Selwyn H., additional, D'Inca, Renata, additional, Kupcinskas, Limas, additional, Turcan, Svetlana, additional, Magro, Fernando, additional, Goldis, Adrian, additional, Hernandez, Vicent, additional, Halfvarson, Jonas, additional, Arebi, Naila, additional, Langholz, Ebbe, additional, Lakatos, Peter L., additional, and Munkholm, Pia, additional

Published
2015
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44. Su1945 - Proximity Extension Assay based Proteins Show Immune Cell Specificity and can Diagnose and Predict Outcomes in Inflammatory Bowel Diseases: IBD Character Study

Author

Kalla, Rahul, Adams, Alex, Vatn, Simen, Bergemalm, Daniel, Ricanek, Petr, Lindstrøm, Jonas, Ocklind, Anette, Nordberg, Niklas, Kennedy, Nicholas, Ventham, Nicholas, IBD Character Consortium, Vatn, Morten H., Söderholm, Johan, Pierik, Marie, Törkvist, Leif, Gomollon, Fernando, Jahnsen, Jorgen, Halfvarson, Jonas, and Satsangi, Jack

Published
2017
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45. Su1827 - Epigenetic Alterations at Diagnosis Predict Susceptibility, Prognosis and Treatment Escalation in Inflammatory Bowel Disease and IBD Character

Author

Kalla, Rahul, Adams, Alex, Vatn, Simen, Bonfiglio, Ferdinando, Nimmo, Elaine, Kennedy, Nicholas, Ventham, Nicholas, Consortium, IBD Character, Vatn, Morten H., Ricanek, Petr, Bergemalm, Daniel, Halfvarson, Jonas, Söderholm, Johan, Pierik, Marie, Törkvist, Leif, Gomollon, Fernando, Gut, Ivo, Jahnsen, Jorgen, and Satsangi, Jack

Published
2017
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46. Sa1114 The Cost of Medical Management, Surgery and Clinical Investigations in a European Population-Based Inception Cohort From the Biological Era – An ECCO-Epicom Study

Author

Burisch, Johan, primary, Pedersen, Natalia, additional, Cukovic-Cavka, Silvija, additional, Kaimakliotis, John, additional, Duricova, Dana., additional, Shonova, Olga, additional, Vind, Ida, additional, Thorsgaard, Niels, additional, Andersen, Vibeke, additional, Dahlerup, Jens F., additional, Salupere, Riina, additional, Nielsen, Kári R., additional, Manninen, Pia, additional, Tsianos, Epameinondas V., additional, Ladefoged, Karin, additional, Bailey, Yvonne, additional, D'Inca, Renata, additional, Kupcinskas, Limas, additional, Turcan, Svetlana, additional, Magro, Fernando, additional, Goldis, Adrian, additional, Belousova, Elena, additional, Hernandez, Vicent, additional, Almer, Sven, additional, Halfvarson, Jonas, additional, Sebastian, Shaji, additional, Lakatos, Peter L., additional, Langholz, Ebbe, additional, Odes, Selwyn H., additional, and Munkholm, Pia, additional

Published
2014
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47. 6 Thiopurine Induced Pancreatitis in Inflammatory Bowel Disease: Clinical Features and Genetic Determinants

Author

Heap, Graham A., primary, Singh, Abhey, additional, Bewshea, Claire M., additional, Weedon, Michael, additional, Dubois, Patrick, additional, Andrews, Jane M., additional, Annese, Vito, additional, Bampton, Peter A., additional, Bell, Sally, additional, Cole, Andy, additional, Connor, Susan J., additional, Creed, Tom, additional, D'Amato, Mauro, additional, Fedorak, Richard N., additional, Florin, Timothy H., additional, Gaya, Daniel R., additional, Greig, Emma, additional, Halfvarson, Jonas, additional, Irving, Peter M., additional, Karban, Amir, additional, Lawrance, Ian C., additional, Lev-Tzion, Raffi, additional, Lindsay, James O., additional, Mawsley, Joel, additional, Mazher, Zia, additional, Orchard, Timothy R., additional, Radford-Smith, Graham L., additional, Reffitt, David, additional, Silverberg, Mark S., additional, Sturniolo, Giacomo C., additional, Tsianos, Epameinondas V., additional, Walsh, Alissa, additional, Zeissig, Sebastian, additional, Holden, Arthur L., additional, and Ahmad, Tariq, additional

Published
2014
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48. 1003 Association of Protective IL13 Polymorphism With Irritable Bowel Syndrome

Author

Wouters, Mira M., primary, Lambrechts, Diether, additional, Cleynen, Isabelle, additional, Whorwell, Peter J., additional, Lambaerts, Kathleen, additional, Agreus, Lars, additional, Dlugosz, Aldona, additional, Schmidt, Peter T., additional, Halfvarson, Jonas, additional, Simren, Magnus, additional, Ohlsson, Bodil, additional, Karling, Pontus, additional, Van Wanrooy, Sander, additional, Vermeire, Severine, additional, Lindberg, Greger, additional, Spiller, Robin C., additional, D'Amato, Mauro, additional, and Boeckxstaens, Guy E., additional

Published
2012
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49. Tu1933 Influence of Genetics in the Expression of Serological Markers in Twins With IBD

Author

Amcoff, Karin, primary, Joossens, Marie, additional, Pierik, Marie J., additional, Jonkers, Daisy, additional, Bohr, Johan, additional, Joossens, Sofie, additional, Romberg-Camps, Mariëlle, additional, Nyhlin, Nils, additional, Wickbom, Anna K., additional, Rutgeerts, Paul J., additional, Tysk, Curt, additional, Bodin, Lennart, additional, Colombel, Jean-Frederic, additional, Vermeire, Severine, additional, and Halfvarson, Jonas, additional

Published
2012
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50. Mo1004 Is There an East-West Gradient in the Incidence of IBD in Europe? and Further Far East in China? First Results From the Epicom Study

Author

Burisch, Johan, primary, Xia, Bing, additional, Cukovic-Cavka, Silvija, additional, Kaimakliotis, John, additional, Duricova, Dana, additional, Shonova, Olga, additional, Vind, Ida, additional, Pedersen, Natalia, additional, Langholz, Ebbe, additional, Thorsgaard, Niels, additional, Andersen, Vibeke, additional, Dahlerup, Jens F., additional, Salupere, Riina, additional, Nielsen, Kári R., additional, Manninen, Pia, additional, Tsianos, Epameinondas V., additional, Ladefoged, Karin, additional, Bjornsson, Einar, additional, Bailey, Yvonne, additional, Odes, Selwyn H., additional, Martinato, Matteo, additional, Kupcinskas, Limas, additional, Turcan, Svetlana I., additional, Magro, Fernando, additional, Goldis, Adrian, additional, Belousova, Elena, additional, Hernandez, Vicent, additional, Almer, Sven, additional, Halfvarson, Jonas, additional, Arebi, Naila, additional, Sebastian, Shaji, additional, Lakatos, Peter L., additional, and Munkholm, Pia S., additional

Published
2012
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