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Your search keyword '"Montserrat Vera Llonch"' showing total 5 results
Start Over Author "Montserrat Vera Llonch" Journal gastroenterology
5 results on '"Montserrat Vera Llonch"'

4. Sa1049 Predictors of Days Unable to Work Among Genotype 1 Treatment-NaïVE Chronic Hepatitis C Patients: Post-Hoc Analyses of Data From Phase 3 Advance and Illuminate Studies

Author

Montserrat Vera-Llonch, Jyoti Aggarwal, Ning C. Hernandez, Zobair M. Younossi, Mrudula Donepudi, and Thomas F. Goss

Subjects
medicine.medical_specialty, Hepatology, Post hoc, business.industry, Gastroenterology, medicine.disease, Phase (combat), Therapy naive, Chronic hepatitis, Internal medicine, Genotype, Medicine, Medical emergency, business
Published
2012
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5. Sa1048 Health-Related Quality-of-Life Among Genotype 1 Treatment-NaïVE Chronic Hepatitis C Patients Receiving Telaprevir Combination Treatment: Post-Hoc Analyses of Data From the Advance Trial

Author

Ning C. Hernandez, Mrudula Donepudi, Martha S. Bayliss, Thomas F. Goss, Zobair M. Younossi, Marie Martin, Jyoti Aggarwal, and Montserrat Vera-Llonch

Subjects
Health related quality of life, HBsAg, medicine.medical_specialty, Hepatology, Post hoc, business.industry, Gastroenterology, virus diseases, digestive system diseases, Telaprevir, Therapy naive, Combined treatment, Chronic hepatitis, Internal medicine, Genotype, medicine, business, medicine.drug
Abstract

combined with less than 1 log10 decline of HBV DNA at week 12 is the best early predictor of nonresponder revealed very high negative predictive value (NPV) and sensitivity (100% and 100%, respectively) with higher positive predictive value (PPV) and specificity (40% and 44%, respectively). Conclusions: This study suggests that treatment with peginterferon alpha-2a had high rate of HBsAg loss even in genotype C. Combination of HBsAg level and Hepatitis B viral load reduction at week 12 is very useful to predict SVR. With very high NPV, these values may be useful for early stopping rule.

Published
2012
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