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Your search keyword '"Colitis, Collagenous chemically induced"' showing total 2 results
Start Over Descriptor "Colitis, Collagenous chemically induced" Journal gastrointestinal endoscopy
2 results on '"Colitis, Collagenous chemically induced"'

1. Unique endoscopy findings in collagenous colitis.

Author

Couto G, Bispo M, Barreiro P, Monteiro L, and Matos L

Subjects
2-Pyridinylmethylsulfinylbenzimidazoles therapeutic use, Anti-Inflammatory Agents, Non-Steroidal therapeutic use, Anti-Ulcer Agents therapeutic use, Biopsy, Cicatrix diagnosis, Cicatrix pathology, Colitis, Collagenous diagnosis, Colitis, Collagenous pathology, Drug Therapy, Combination, Female, Gastrointestinal Hemorrhage chemically induced, Gastrointestinal Hemorrhage diagnosis, Gastrointestinal Hemorrhage pathology, Humans, Intestinal Mucosa pathology, Intestinal Perforation chemically induced, Intestinal Perforation diagnosis, Intestinal Perforation pathology, Lansoprazole, Middle Aged, Sulfonamides therapeutic use, 2-Pyridinylmethylsulfinylbenzimidazoles adverse effects, Anti-Inflammatory Agents, Non-Steroidal adverse effects, Anti-Ulcer Agents adverse effects, Colitis, Collagenous chemically induced, Colon, Transverse pathology, Colonoscopy, Osteoarthritis drug therapy, Sulfonamides adverse effects
Published
2009
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2. Linear mucosal defect may be characteristic of lansoprazole-associated collagenous colitis.

Author

Umeno J, Matsumoto T, Nakamura S, Jo Y, Yada S, Hirakawa K, Yoshimura R, Yamagata H, Kudo T, Hirano A, Gushima M, Yao T, Nakashima Y, and Iida M

Subjects
2-Pyridinylmethylsulfinylbenzimidazoles therapeutic use, Adult, Aged, Aged, 80 and over, Case-Control Studies, Colitis, Collagenous diagnosis, Colonoscopy methods, Dose-Response Relationship, Drug, Drug Administration Schedule, Female, Follow-Up Studies, Gastroesophageal Reflux diagnosis, Gastroesophageal Reflux drug therapy, Humans, Lansoprazole, Male, Middle Aged, Proton Pumps adverse effects, Reference Values, Retrospective Studies, Risk Assessment, Severity of Illness Index, 2-Pyridinylmethylsulfinylbenzimidazoles adverse effects, Colitis, Collagenous chemically induced, Colitis, Collagenous pathology, Intestinal Mucosa pathology, Proton Pump Inhibitors
Abstract

Background: Although some cases of collagenous colitis have been induced by lansoprazole (LPZ), the clinicopathologic features of LPZ-associated collagenous colitis have not been elucidated., Objective: To elucidate the clinical, endoscopic, and histopathologic features of LPZ-associated collagenous colitis., Design: Retrospective case study., Patients: The subjects were 13 patients with collagenous colitis diagnosed during a period from 2002 to 2007., Main Outcome Measurements: The colonoscopic and histopathologic findings were compared retrospectively between 9 cases of LPZ use (LPZ group) and 4 cases without the use of LPZ (non-LPZ group)., Results: A colonoscopy revealed a linear mucosal defect more frequently in the LPZ group (7 of 9 cases [78%]) than in the non-LPZ group (0 of 4 cases [0%], P = .02). Friable mucosa was also noted in 4 patients (44%) in the LPZ group but none in the non-LPZ group. The colonoscopic finding in the non-LPZ group was either normal mucosa or nonspecific minimal abnormalities, whereas patients in the LPZ group had either a linear mucosal defect, mucosal bleeding, or both (P = .001). On histologic examination, the subepithelial collagen band was thicker in patients in the LPZ group than in those in the non-LPZ group (median 45 vs 26.3 mum). All patients in the LPZ group recovered from diarrhea after discontinuance of LPZ., Limitation: A small number of patients., Conclusions: Linear mucosal defects and friable mucosa may be characteristic colonoscopic findings in cases of LPZ-associated collagenous colitis.

Published
2008
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