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Water-based hydraulic fracturing for the exploitation of shale gas reservoirs may be limited by two main factors: (1) water pollution and chemical pollution after the injection process and (2) permeability decrease due to clay mineral swelling upon contact with the injection water. Besides, shale rock nearly always contains fractures and fissures due to geological processes such as deposition and folding. Based on the above, a damage-based coupled model of rock deformation and gas flow is used to simulate the fracturing process in jointed shale wells with CO2 fracturing. We validate our model by comparing the simulation results with theoretical solutions. The research results show that the continuous main fractures are formed along the direction of the maximum principal stress, whilst hydraulic fractures tend to propagate along the preexisting joints due to the lower strength of the joints. The main failure type is tensile damage destruction among these specimens. The preexisting joints can aggravate the damage of the numerical specimens; the seepage areas of the layered jointed sample, vertical jointed sample, and orthogonal jointed sample are increased by 32.5%, 29.16%, and 35.05%, respectively, at time t=39 s compared with the intact sample. The preexisting horizontal joints or vertical joints promote the propagation of hydraulic fractures in the horizontal direction or vertical direction but restrain the expansion of hydraulic fractures in the vertical or horizontal direction. [ABSTRACT FROM AUTHOR]