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Abstract: Four sets of remote sensing images from 1987, 1994, 2000, and 2006, 50 years of meteorological and soil moisture data corresponding to different desertified lands were combined with populations and livestock data to analyze the process and cause of desertification in a portion of the Qinghai–Tibetan Plateau (QTP). It showed that surface soil temperature in the region has increased at an average rate of 0.6 °C per decade between 1980 and 2005, the thawing days on the surface have increased by 60 days from 1983 to 2001, and the depth of the seasonal thawing layer has increased by 54 cm, 102 cm and 77 cm in April, May and June, respectively, from 1983 to 2003. As a result, the upper soil layer has become drier due to the thickening active layer and soil water infiltration. These changes, in turn, have inhibited the growth of alpine meadow vegetation that has shallow root systems. It is concluded that climate warming and permafrost thawing have caused desertification in grazing regions of the Qinghai–Tibetan Plateau (QTP). [Copyright &y& Elsevier]