1. Subjective memory impairment, objective cognitive functioning and social activity in French older people: findings from the Three Cities study
- Author
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Genziani, Mirella, Stewart, Robert, Béjot, Yannick, Amieva, Hélène, Artero, Sylvaine, Ritchie, Karen, Institute of Psychiatry, Queen Mary University of London (QMUL)-King‘s College London, Neuropsychiatrie : recherche épidémiologique et clinique (PSNREC), Université Montpellier 1 (UM1)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Service de Neurologie, Université Montpellier 1 (UM1)-Hôpital Guy de Chauliac-Centre Mémoire Ressources Recherche Languedoc - Roussillon, Epidémiologie, santé publique et développement, Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR99-ISPED, Faculty of Medicine, Imperial College London, Inserm, Victor Segalen - Bordeaux II Université, Sanofi-Synthélabo, Fondation pour la Recherche Médicale, Caisse Nationale Maladie des Travailleurs Salariés, Direction Générale de la Santé, MGEN, Institut de la Longévité, Agence Française de Sécurité Sanitaire des Produits de Santé, Régions Aquitaine, Bourgogne et Languedoc-Roussillon, Fondation de France, Ministère de la Recherche-Inserm Programme 'Cohortes et collection de données biologiques'., Villebrun, Dominique, and Université Montpellier 1 (UM1)-Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)
- Subjects
Male ,MESH: Chi-Square Distribution ,MESH: Social Support ,social activity ,MESH: Logistic Models ,Neuropsychological Tests ,older people ,Prevalence ,Humans ,[SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] ,cognitive function ,MESH: Prevalence ,Aged ,MESH: Aged ,Memory Disorders ,MESH: Humans ,Chi-Square Distribution ,[SDV.MHEP.GEG] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology ,[SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology ,Social Support ,MESH: Neuropsychological Tests ,MESH: Memory Disorders ,MESH: Male ,MESH: France ,MESH: Cognition Disorders ,Logistic Models ,[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie ,subjective memory impairment ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] ,Female ,France ,Cognition Disorders ,MESH: Female - Abstract
International audience; AIM: To investigate the association between subjective memory impairment (SMI) and objective cognitive impairment in later life, and to ascertain whether this is modified by level of social activity, education or living alone. METHODS: Data were analyzed from three French community surveys carried out in Bordeaux, Dijon and Montpellier. Representative samples of 9294 residents aged 65 years and over were included in the study. SMI was ascertained and investigated in relation to performance on the Benton Visual Retention Test (BVRT), the Isaac Set Test (IST) and Trail Making Test B (TMT). Adjustments were made for age, sex, education, depressive symptoms (Centre for Epidemiological Depression scale), site where study was carried out and living alone. Stratified analyses investigated modification by high or low social activity, education or living arrangement. RESULTS: SMI was reported by 21.9% of the sample, and was significantly associated with lower scores on BVRT and TMT after adjustment for age, sex, education, depressive symptoms, site and living alone. These associations were not significantly modified by social activity, education or living alone. CONCLUSION: Worse subjective memory was associated independently with worse performance on two tests of cognitive function; however, in these cohorts, no evidence was found for modification of associations by social activity/support or education.
- Published
- 2012
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