1. 'TO ESTIMATE VITAMIN D DEFICIENCY IN OBESE AND NON OBESE FEMALES WITH TYPE 2 DIABETES MELLITUS IN NORTH INDIA'
- Author
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Satya Prakash Tripathi, Smriti Singh, Anubha Srivastava, and Ashutosh Pathak
- Subjects
Control and Optimization ,Applied Mathematics ,Mechanical Engineering ,General Engineering ,Biomedical Engineering ,Biophysics ,Aerospace Engineering ,General Physics and Astronomy ,Ocean Engineering ,Statistical and Nonlinear Physics ,General Medicine ,Computer Science Applications ,Computational Mathematics ,Mathematics (miscellaneous) ,Control and Systems Engineering ,Electrical and Electronic Engineering ,General Economics, Econometrics and Finance ,Analysis ,Mathematical Physics ,Social Sciences (miscellaneous) - Abstract
Background: Vitamin D deciency is prevalent among obese individuals. Some authors have postulated that Vitamin D is sequestered in the excess adipose tissue, leading to less bioavailability, whereas others suggest that low Serum 25-hydroxy Vitamin D may be a result of volumetric dilution of vitamin D in the large adipose stores. Aim: To study and compare the Vitamin D levels in Obese and Non-obese diabetic female with obese and Non-obese nondiabetic females. Method & Materials: The present study was conducted in the Department of Medicine, MLN Medical College & SRN Hospital, Prayagraj to assess Vitamin D levels of diabetic and non-diabetic obese and non-obese females. A total of 115 diabetic female patients attending Clinic fullling the inclusion criteria and giving consent were included as Cases and 115 female non-diabetic patients without active or chronic problems attending different departments were included in the study. Serum samples of all the participants were collected for estimation of 25-hydroxy vitamin D (25-OH vitamin D). Quantitative determination of 25- hydroxy vitamin D (25- OH vitamin D) in human serum is done by chemiluminescent microparticle immunoassay (CMIA). Result: Majority of Controls had Normal Vitamin D levels (52.2%) , on the other hand only 1.7% cases had normal Vitamin D levels. Vast majority of Cases (98.3%) had Vitamin D deciency. Higher percentage of Cases were found to have mild and severe vitamin D deciency as compared to that in controls. [Mild Vitamin D deciency -12.2% vs. 11.3% in cases and controls respectively and severe Vitamin D deciency - 86.1% vs. 36.5% in cases and controls respectively] . Difference in vitamin D status of Cases and Controls was found to be signicant statistically. Serum Vitamin D levels of Controls (29.18±20.31 ng/ml) was found to be signicantly higher as compared to Cases (9.06±6.03 ng/ml). Conclusion- Mean serum vitamin D levels were signicantly lower in Diabetic females as compared to that in Non-Diabetic females.Obesity was associated with a signicantly lower vitamin D levels in both Diabetic females as well as Non-Diabetic females. more...
- Published
- 2023
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