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Your search keyword '"Viswanathan, Akila"' showing total 33 results
Start Over Author "Viswanathan, Akila" Journal gynecologic oncology
33 results on '"Viswanathan, Akila"'

2. Corrigendum to “Beyond Sedlis—A novel histology-specific nomogram for predicting cervical cancer recurrence risk: An NRG/GOG ancillary analysis” [Gynecologic Oncology 162 (2021) 532–538]

Author

Levinson, Kimberly, Beavis, Anna L, Purdy, Christopher, Rositch, Anne F, Viswanathan, Akila, Wolfson, Aaron H, Kelly, Michael G, Tewari, Krishnansu S, McNally, Leah, Guntupalli, Saketh R, Ragab, Omar, Lee, Yi-Chun, Miller, David S, Huh, Warner K, Wilkinson, Kelly J, Spirtos, Nicola M, Le, Linda Van, Casablanca, Yovanni, Holman, Laura L, Waggoner, Steven E, and Fader, Amanda N

Subjects
Reproductive Medicine, Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Paediatrics and Reproductive Medicine, Oncology & Carcinogenesis, Clinical sciences, Oncology and carcinogenesis, Reproductive medicine
Abstract

The authors regret that the version of Table 3 originally published in this article was incorrect. The online version has now been updated and the correct table can be found below. The authors would like to apologise for any inconvenience caused. Table 3. Comparison of 3 yr RFS, nomogram recurrence risk, and Sedlis criteria for predictor variable combinations. [Table Presented]

Published
2021

3. Beyond Sedlis—A novel histology-specific nomogram for predicting cervical cancer recurrence risk: An NRG/GOG ancillary analysis

Author

Levinson, Kimberly, Beavis, Anna L, Purdy, Christopher, Rositch, Anne F, Viswanathan, Akila, Wolfson, Aaron H, Kelly, Michael G, Tewari, Krishnansu S, McNally, Leah, Guntupalli, Saketh R, Ragab, Omar, Lee, Yi-Chun, Miller, David S, Huh, Warner K, Wilkinson, Kelly J, Spirtos, Nicola M, Van Le, Linda, Casablanca, Yovanni, Holman, Laura L, Waggoner, Steven E, and Fader, Amanda N

Subjects
Cancer, Adenocarcinoma, Adult, Carcinoma, Squamous Cell, Female, Humans, Middle Aged, Neoplasm Invasiveness, Neoplasm Recurrence, Local, Neoplasm Staging, Nomograms, Proportional Hazards Models, Randomized Controlled Trials as Topic, Risk Factors, Uterine Cervical Neoplasms, Cervical cancer, Stage I, Adjuvant radiation, Oncology and Carcinogenesis, Paediatrics and Reproductive Medicine, Oncology & Carcinogenesis
Abstract

PurposeThe Sedlis criteria define risk factors for recurrence warranting post-hysterectomy radiation for early-stage cervical cancer; however, these factors were defined for squamous cell carcinoma (SCC) at an estimated recurrence risk of ≥30%. Our study evaluates and compares risk factors for recurrence for cervical SCC compared with adenocarcinoma (AC) and develops histology-specific nomograms to estimate risk of recurrence and guide adjuvant treatment.MethodsWe performed an ancillary analysis of GOG 49, 92, and 141, and included stage I patients who were surgically managed and received no neoadjuvant/adjuvant therapy. Multivariable Cox proportional hazards models were used to evaluate independent risk factors for recurrence by histology and to generate prognostic histology-specific nomograms for 3-year recurrence risk.ResultsWe identified 715 patients with SCC and 105 with AC; 20% with SCC and 17% with AC recurred. For SCC, lymphvascular space invasion (LVSI: HR 1.58, CI 1.12-2.22), tumor size (TS ≥4 cm: HR 2.67, CI 1.67-4.29), and depth of invasion (DOI; middle 1/3, HR 4.31, CI 1.81-10.26; deep 1/3, HR 7.05, CI 2.99-16.64) were associated with recurrence. For AC, only TS ≥4 cm, was associated with recurrence (HR 4.69, CI 1.25-17.63). For both histologies, there was an interaction effect between TS and LVSI. For those with SCC, DOI was most associated with recurrence (16% risk); for AC, TS conferred a 15% risk with negative LVSI versus a 25% risk with positive LVSI.ConclusionsCurrent treatment standards are based on the Sedlis criteria, specifically derived from data on SCC. However, risk factors for recurrence differ for squamous cell and adenocarcinoma of the cervix. Histology-specific nomograms accurately and linearly represent risk of recurrence for both SCC and AC tumors and may provide a more contemporary and tailored tool for clinicians to base adjuvant treatment recommendations to their patients with cervical cancer.

Published
2021

7. Adjuvant therapy for early stage, endometrial cancer with lymphovascular space invasion: Is there a role for chemotherapy?

Author

Beavis, Anna L., Yen, Ting-Tai, Stone, Rebecca L., Wethington, Stephanie L., Carr, Caitlin, Son, Ji, Chambers, Laura, Michener, Chad M., Ricci, Stephanie, Burkett, Wesley C., Richardson, Debra L., Staley, Allison-Stuart, Ahn, Susie, Gehrig, Paola A., Torres, Diogo, Dowdy, Sean C., Sullivan, Mackenzie W., Modesitt, Susan C., Watson, Catherine, Veade, Ashely, Ehrisman, Jessie, Havrilesky, Laura, Secord, Angeles Alvarez, Loreen, Amy, Griffin, Kaitlyn, Jackson, Amanda, Viswanathan, Akila N., Jager, Leah R., and Fader, Amanda N.

Published
2020
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28. The ASTRO clinical practice guidelines in cervical cancer: Optimizing radiation therapy for improved outcomes

Author

Chino, Junzo, primary, Annunziata, Christina M., additional, Beriwal, Sushil, additional, Bradfield, Lisa, additional, Erickson, Beth A., additional, Fields, Emma C., additional, Fitch, Jane, additional, Harkenrider, Matthew M., additional, Holschneider, Christine H., additional, Kamrava, Mitchell, additional, Leung, Eric, additional, Lin, Lilie L., additional, Mayadev, Jyoti S., additional, Morcos, Marc, additional, Nwachukwu, Chika, additional, Petereit, Daniel, additional, and Viswanathan, Akila N., additional

Published
2020
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31. Corrigendum to “comparison of outcomes for MR-guided versus CT-guided high-dose-rate interstitial brachytherapy in women with locally advanced carcinoma of the cervix” [Gynecol. Oncol. 145 (2017) 284–290]

Author

Kamran, Sophia C., primary, Manuel, Matthias M., additional, Cho, Linda P., additional, Damato, Antonio L., additional, Schmidt, Ehud J., additional, Tempany, Clare, additional, Cormack, Robert A., additional, and Viswanathan, Akila N., additional

Published
2017
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