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Start Over Author "Baron, M." Journal gynecologie obstetrique & fertilite
10 results on '"Baron, M."'

10. Intérêt pronostique de la TEP-TDM au 18F-FDG dans le bilan initial du cancer du col de l’utérus : étude rétrospective de 53 cas

Author

Chastan, M., Manrique, A., Baron, M., Edet Sanson, A., Diologent, B., Vera, P., and Hitzel, A.

Subjects
*CERVICAL cancer, *CANCER invasiveness, *MAGNETIC resonance imaging, *LYMPH node diseases, *POSITRON emission tomography, *RETROSPECTIVE studies, *FOLLOW-up studies (Medicine), *MULTIVARIATE analysis, *PROGNOSIS
Abstract

Abstract: Objectives: Assessment of prognostic value of pretherapeutic 18F-FDG PET/CT (PET). Patients and methods: Retrospective study of 53 patients with invasive uterine cervix carcinoma. Each patient has been evaluated with pretherapeutic whole-body FDG PET/CT and pelvic MRI. Minimal follow-up lasted for 1 year. On PET/CT, we have visually analyzed metabolism of primary tumor, pelvic and para-aortic lymph nodes in comparison with surrounding structures. We have compared prognostic factors as pretherapeutic haemoglobin rate, FIGO staging, MRI and PET/CT data using Mann-Whitney univariate analysis and Cox multivariate analysis. Results: Para-aortic lymph node abnormal uptake on PET/CT was the only independent predictor of progression-free survival. Pelvic lymph node involvement on PET/CT was the only independent predictor of overall survival. MRI did not provide any additional information. Discussion and conclusion: Lymph node involvement visually assessed by 18F-FDG PET/CT was the most significant prognostic factor for overall and progression-free survival. [Copyright &y& Elsevier]

Published
2010
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