Search

Your search keyword '"Willems, Stefan M."' showing total 13 results
Start Over Author "Willems, Stefan M." Journal head & neck
13 results on '"Willems, Stefan M."'

3. Impact of chemotherapy on the outcome of osteosarcoma of the head and neck in adults

Author

Boon, Eline, van der Graaf, Winette T. A., Gelderblom, Hans, Tesselaar, Margot E. T., van Es, Robert J. J., Oosting, Sjoukje F., de Bree, Remco, van Meerten, Esther, Hoeben, Ann, Smeele, Ludi E., Willems, Stefan M., Witjes, Max J. H., Buter, Jan, Baatenburg de Jong, Robert J., Flucke, Uta E., Peer, Petronella G. M., Bovée, Judith V. M. G., and Van Herpen, Carla M. L.

Published
2017
Full Text
View/download PDF

7. HIF‐1a expression and differential effects on survival in patients with oral cavity, larynx, and oropharynx squamous cell carcinomas.

Author

Swartz, Justin E., Wegner, Inge, Noorlag, Rob, Kempen, Pauline M. W., Es, Robert J. J., Bree, Remco, and Willems, Stefan M. W.

Subjects
SQUAMOUS cell carcinoma, PROGNOSIS, LARYNX, HYPOXIA-inducible factors, OROPHARYNX
Abstract

Background: Hypoxia is a negative prognostic factor in head and neck squamous cell carcinomas. Under hypoxia, the hypoxia‐inducible factor (HIF)‐1a transcription factor is overexpressed. We investigated whether there were site differences in HIF‐1a expression and its effect on patient outcomes per subsite. Design/Method: A total of 941 patients with HNSCC in the squamous cell carcinoma of the oropharynx (OPSCC, n = 302), oral cavity (OSCC, n = 391), or larynx (LSCC, n = 248) were included. Expression of HIF‐1a in tissue samples was investigated using immunohistochemistry. Overall survival (OS), disease‐free survival (DFS), and locoregional control (LRC) were analyzed. Results: HIF‐1a expression was higher in OSCC than in LSCC and OPSCC. High HIF‐1a expression led to worse prognosis in OPSCC (OS P =.029, DFS P =.085) and LSCC (OS P =.041, DFS P =.011) and better in OSCC (OS P =.055, DFS P =.012). There was no association between HIF‐1a and LRC. Conclusions: High HIF‐1a expression is related to poor outcome in OPSCC and LSCC and better outcome in OSCC. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

11. Impact of chemotherapy on the outcome of osteosarcoma of the head and neck in adults

Author

Boon, Eline, primary, van der Graaf, Winette T. A., additional, Gelderblom, Hans, additional, Tesselaar, Margot E. T., additional, van Es, Robert J. J., additional, Oosting, Sjoukje F., additional, de Bree, Remco, additional, van Meerten, Esther, additional, Hoeben, Ann, additional, Smeele, Ludi E., additional, Willems, Stefan M., additional, Witjes, Max J. H., additional, Buter, Jan, additional, Baatenburg de Jong, Robert J., additional, Flucke, Uta E., additional, Peer, Petronella G. M., additional, Bovée, Judith V. M. G., additional, and Van Herpen, Carla M. L., additional

Published
2016
Full Text
View/download PDF

12. Correlation of human papillomavirus status with apparent diffusion coefficient of diffusion-weighted MRI in head and neck squamous cell carcinomas

Author

Driessen, Juliette P., primary, van Bemmel, Alexander J. M., additional, van Kempen, Pauline M. W., additional, Janssen, Luuk M., additional, Terhaard, Chris H. J., additional, Pameijer, Frank A., additional, Willems, Stefan M., additional, Stegeman, Inge, additional, Grolman, Wilko, additional, and Philippens, Marielle E.P., additional

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results