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'The incubation period, the time between infection and disease onset, is important in the Surveillance and control of infectious diseases but is often coarsely observed. Coarse data arises because the [...]

'The objectives of this study, were to establish and describe a database of Cochrane and non-Cochrane meta-analyses of safety data and to determine Under what conditions exact methods differ from [...]

According to recent research from Netherlands, 'Many studies on optimal designs for linear mixed model analysis of repeated measures data have focussed on estimating the fixed effects. The present study [...]

'Multi-state models are frequently applied to describe transitions over time between three states: healthy, not healthy and death. The three-state model can be used to estimate life expectancies in health [...]

'To date, despite widespread availability of time series data on multiple syndromes, multivariate analysis of syndromic data remains under-explored (see also Statistics). We present a non-parametric multivariate framework for early [...]

'In clinical studies, it is common to compare several treatments with a control (see also Statistics). In such cases, the most popular statistical technique is the Dunnett procedure,' investigators in [...]

'Developmental indicators that are used for routine measurement in The Netherlands are usually chosen to optimally identify delayed children. Measurements on the majority of children without problems are therefore quite [...]