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Your search keyword '"Thymidine -- Genetic aspects"' showing total 8 results
Start Over Descriptor "Thymidine -- Genetic aspects" Journal health & medicine week
8 results on '"Thymidine -- Genetic aspects"'

1. Reports outline gene therapy study results from N. Solaroli et al

Subjects
Cancer -- Genetic aspects, Cancer -- Reports, Phosphotransferases -- Genetic aspects, Phosphotransferases -- Reports, Gene therapy -- Genetic aspects, Gene therapy -- Reports, Genetic research -- Genetic aspects, Genetic research -- Reports, Thymidine -- Genetic aspects, Thymidine -- Reports, Adenosine kinase -- Genetic aspects, Adenosine kinase -- Reports, Nucleoside analogs -- Genetic aspects, Nucleoside analogs -- Reports, Cancer -- Research
Abstract

According to a study from Stockholm, Sweden, "The multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster deoxyribonucleoside kinase (Dm-dNK) is studied as a candidate suicide gene for applications in combined gene/chemotherapy of [...]

Published
2008

2. HIV-1 RT K65R and thymidine analog mutations exhibit bidirectional phenotypic antagonism

Subjects
Highly active antiretroviral therapy -- Reports, Highly active antiretroviral therapy -- Genetic aspects, Thymidine -- Reports, Thymidine -- Genetic aspects, HIV (Viruses) -- Reports, HIV (Viruses) -- Genetic aspects
Abstract

HIV-1 reverse transcriptase K65R and thymidine analog mutations exhibit bidirectional phenotypic antagonism. According to a study from the United States, "The K65R mutation in human immunodeficiency virus type 1 (HIV-1) [...]

Published
2006

3. Viral fitness contributes substantially to evolutionary pattern of thymidine analog mutations

Subjects
Yale University, Drug resistance -- Care and treatment, Drug resistance -- Genetic aspects, Thymidine -- Genetic aspects, Antiviral agents -- Genetic aspects, HIV (Viruses) -- Care and treatment, HIV (Viruses) -- Genetic aspects, Virus diseases -- Care and treatment, Virus diseases -- Genetic aspects
Abstract

HIV viral fitness contributes substantially to the evolutionary pattern of thymidine analog mutations. "All currently recommended antiretroviral therapy protocols employ reverse transcriptase inhibitors (RTIs). However, mutations within the reverse transcriptase [...]

Published
2006

4. Mouse lymphoma thymidine kinase gene mutation assay is described

Subjects
Gene mutations -- Genetic aspects, Genetic research -- Genetic aspects, Lymphomas -- Genetic aspects, Thymidine -- Genetic aspects, Cancer -- Genetic aspects, Mice -- Genetic aspects
Abstract

Scientists describe the mouse lymphoma thymidine kinase gene mutation assay in a recent issue of Environmental and Molecular Mutagenesis. According to an international team of researchers, 'The Mouse Lymphoma Assay [...]

Published
2006

5. Diversity of thymidine analogue resistance genotypes in HIV reported

Subjects
Anti-infective agents -- Genetic aspects, Highly active antiretroviral therapy -- Genetic aspects, Genotype -- Genetic aspects, Drug resistance -- Genetic aspects, Thymidine -- Genetic aspects, HIV (Viruses) -- Genetic aspects
Abstract

A researcher reports the diversity of thymidine analogue resistance genotypes among newly diagnosed HIV-1-infected individuals in a recent issue of the Journal of Antimicrobial Chemotherapy. "The introduction of highly active [...]

Published
2005

6. Diversity of thymidine resistance genotypes HIV discussed

Subjects
Anti-infective agents -- Genetic aspects, Genotype -- Genetic aspects, Drug resistance -- Genetic aspects, Thymidine -- Genetic aspects, HIV (Viruses) -- Genetic aspects
Abstract

A researcher discusses the diversity of thymidine analogue resistance genotypes among newly diagnosed HIV-1-infected people in a recent issue of the Journal of Antimicrobial Chemotherapy. According to recent research from [...]

Published
2005

7. Herpes simplex virus thymidine kinase transduction expands colon cancer growth

Subjects
Company growth, Herpes simplex -- Genetic aspects, Herpes simplex -- Reports, Herpes simplex -- Growth, Cancer -- Genetic aspects, Cancer -- Reports, Cancer -- Growth, Communicable diseases -- Genetic aspects, Communicable diseases -- Reports, Communicable diseases -- Growth, Gene therapy -- Genetic aspects, Gene therapy -- Reports, Gene therapy -- Growth, Prostanoids -- Genetic aspects, Prostanoids -- Reports, Prostanoids -- Growth, Herpes simplex virus -- Genetic aspects, Herpes simplex virus -- Reports, Herpes simplex virus -- Growth, Virus diseases -- Genetic aspects, Virus diseases -- Reports, Virus diseases -- Growth, Thymidine -- Genetic aspects, Thymidine -- Reports, Thymidine -- Growth, Colon cancer -- Genetic aspects, Colon cancer -- Reports, Colon cancer -- Growth
Abstract

Herpes simplex virus thymidine kinase transduction expands colon cancer growth. "Transduction of tumor cells with herpes simplex virus thymidine kinase (HSV-tk) gene and subsequent treatment with the prodrug ganciclovir (GCV) [...]

Published
2005

8. K65R mutations correlate negatively with thymidine analogue mutations

Subjects
Thymidine -- Genetic aspects
Abstract

K65R resistance mutations correlate negatively with thymidine analogue mutations. "Over the past 5 years, 1846 HIV-infected patients underwent drug resistance testing at our institution. None out of 216 drug-naive subjects [...]

Published
2005

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