1. Right bundle branch block and risk of cardiovascular mortality: the Ibaraki Prefectural Health Study
- Author
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Takuji Tomizawa, Akihiko Nogami, Dongzhu Xu, Kimi Sato, Fujiko Irie, Hiroyasu Iso, Yasushi Kawakami, Hitoshi Ota, Kazumasa Yamagishi, Naoto Kawamatsu, Naomi Nakazawa, Tomofumi Nakatsukasa, Nobuyuki Murakoshi, Daishi Nakagawa, Masayoshi Yamamoto, Tomoko Machino-Otsuka, Toshimi Sairenchi, Kazutaka Aonuma, Tomoko Ishizu, and Masaki Ieda
- Subjects
Male ,medicine.medical_specialty ,Bundle-Branch Block ,Population ,Cardiovascular System ,Asymptomatic ,Cohort Studies ,Electrocardiography ,Japan ,Internal medicine ,Epidemiology ,medicine ,Humans ,education ,Aged ,education.field_of_study ,Proportional hazards model ,business.industry ,Hazard ratio ,Middle Aged ,Right bundle branch block ,medicine.disease ,Confidence interval ,Female ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Cohort study - Abstract
Historically, a right bundle branch block has been considered a benign finding in asymptomatic individuals. However, this conclusion is based on a few old studies with small sample sizes. We examined the association between a complete right bundle branch block (CRBBB) and subsequent cardiovascular mortality in the general population in Japan. In this large community-based cohort study, data of 90,022 individuals (mean age, 58.5 ± 10.2 years; 66.2% women) who participated in annual community-based health check-ups were assessed. Subjects were followed up from 1993 to the end of 2016. Cox proportional hazards’ models and log-rank tests were used for the data analysis. CRBBB was documented in 1,344 participants (1.5%). Among all included participants, CRBBB was associated with an increased risk of cardiovascular mortality after adjustment for all potential confounders (hazard ratio [HR] 1.21; 95% confidence interval [CI] 1.06–1.38). The increased risk of cardiovascular mortality was particularly evident in women aged
- Published
- 2021