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Objective: To report a case of salicylate toxicity treated with continuous venovenous hemodiafiltration (CVVHDF) and review the literature regarding the use of continuous renal replacement therapy (CRRT) for salicylate toxicity., Case: A 16-year-old male presented after ingesting 1901 mg/kg of enteric coated aspirin. Salicylate level was 92 mg/dl 4 h after ingestion. Sequele included seizure, acute kidney injury, pulmonary edema, and prolonged QTc. He received 5.5 h of hemodialysis followed by CVVHDF to continue to augment clearance. His aspirin level fell to 37.4 mg/dl after HD and then to 11.3 mg/dl after nearly 10 h of CVVHDF., Discussion: Cited reasons for the use of CRRT for salicylate toxicity primarily have been hypotension or desire for ongoing augmentation of salicylate clearance in the setting of multiorgan toxicity. CVVHDF may have a role in severe salicylate toxicity to enhance ongoing clearance after an initial round of HD in order to prevent significant rebound., (Published by Elsevier Inc.)

Objective: To describe a relatively rare hypersentivity reaction with pulmonary manifestations in a pediatric patient., Data Sources: Electronic medical records., Study Selection: Patient treatment in the pediatric critical care unit., Data Extraction and Synthesis: Electronic medical records., Conclusions: Eosinophilic pneumonias are rare in the pediatric population. Peripheral eosinophilia is not necessary to make the diagnosis. Bronchoalveolar lavage is the diagnostic study of choice. Lung biopsies are rarely needed to make the diagnosis. The treatment of choice is steroids. If steroids fail to improve the patient's condition, consider IVIG, and cyclosporine A., (Copyright © 2015 Elsevier Inc. All rights reserved.)