1. Transvenous lead extraction: Efficacy and safety of the procedure in female patients
- Author
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Luca Segreti, MD, Maria Grazia Bongiorni, MD, Valentina Barletta, MD, PhD, Matteo Parollo, MD, Andrea Di Cori, MD, Federico Fiorentini, MD, Mario Giannotti Santoro, MD, Raffaele De Lucia, MD, Stefano Viani, MD, Gino Grifoni, MD, Luca Paperini, MD, Ezio Sodati, MD, Lorenzo Mazzocchetti, MD, Antonio Maria Canu, MD, and Giulio Zucchelli, MD, PhD
- Subjects
Transvenous lead extraction ,Sex differences ,Female sex ,Safety outcomes ,Complication ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Background: Existing data on the impact of sex differences on transvenous lead extraction (TLE) outcomes in cardiac device patients are limited. Objective: The purpose of this study was to evaluate the safety and efficacy of mechanical TLE in female patients. Methods: A retrospective evaluation was performed on 3051 TLE patients (group 1: female; group 2: male) from a single tertiary referral center. All individuals received treatment using single sheath mechanical dilation and various venous approaches as required. Results: Our analysis included 3051 patients (group 1: 750; group 2: 2301), with a total of 5515 leads handled with removal. Female patients were younger, had a higher left ventricular ejection fraction, and lower prevalences of coronary artery disease and diabetes mellitus. Infection was more common in male patients, whereas lead malfunction or abandonment were more frequent in female patients. Radiologic success was lower in female patients (95.8% vs 97.5%; P = .003), but there was no significant difference in clinical success between groups (97.2% vs 97.5%; P = .872). However, major complications (1.33% vs 0.60%; P
- Published
- 2023
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