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For further understanding the coal spontaneous combustion in goaf, the dynamic evolution of the oxygen concentration field influenced by the condition of negative pressure of cross-cut were analyzed. Based on the on-site testing results, the range of the oxidation zone on the headentry and tailentry side is determined as 30 ~ 75 m and 15 ~ 65 m respectively. This paper adopts a new method called "fixed grid, dynamic attribute" to dynamically describe the spatial change of goaf caused by working face advancing. The validated model which developed by field measured data is used to study the dynamic evolution of negative pressure impact of cross-cut on oxygen concentration field in goaf. The results demonstrate that when the cross-cut is located at different positions of three zones of coal spontaneous combustion, the negative pressure of the cross-cut has different impact rules on the distribution of oxygen concentration field. The results are hopeful for providing effective guidance for coal mine fire prevention in goaf. [ABSTRACT FROM AUTHOR]