Search

Your search keyword '"Capello, Daniela"' showing total 6 results
Start Over Author "Capello, Daniela" Journal hematological oncology
6 results on '"Capello, Daniela"'

1. Alterations of negative regulators of cytokine signalling in immunodeficiency-related non-Hodgkin lymphoma

Author

Capello, Daniela, primary, Gloghini, Annunziata, additional, Baldanzi, Gianluca, additional, Martini, Maurizio, additional, Deambrogi, Clara, additional, Lucioni, Marco, additional, Piranda, Daniela, additional, Famà, Rosella, additional, Graziani, Andrea, additional, Spina, Michele, additional, Tirelli, Umberto, additional, Paulli, Marco, additional, Larocca, Luigi Maria, additional, Gaidano, Gianluca, additional, Carbone, Antonino, additional, and Sinigaglia, Fabiola, additional

Published
2012
Full Text
View/download PDF

2. Analysis ofSF3B1mutations in monoclonal B-cell lymphocytosis

Author

Greco, Mariangela, primary, Capello, Daniela, additional, Bruscaggin, Alessio, additional, Spina, Valeria, additional, Rasi, Silvia, additional, Monti, Sara, additional, Ciardullo, Carmela, additional, Cresta, Stefania, additional, Fangazio, Marco, additional, Gaidano, Gianluca, additional, Foà, Robin, additional, and Rossi, Davide, additional

Published
2012
Full Text
View/download PDF

3. Analysis of immunoglobulin heavy and light chain variable genes in post‐transplant lymphoproliferative disorders

Author

Capello, Daniela, primary, Cerri, Michaela, additional, Muti, Giuliana, additional, Lucioni, Marco, additional, Oreste, Pierluigi, additional, Gloghini, Annunziata, additional, Berra, Eva, additional, Deambrogi, Clara, additional, Franceschetti, Silvia, additional, Rossi, Davide, additional, Alabiso, Oscar, additional, Morra, Enrica, additional, Rambaldi, Alessandro, additional, Carbone, Antonino, additional, Paulli, Marco, additional, and Gaidano, Gianluca, additional

Published
2006
Full Text
View/download PDF

5. Alterations of negative regulators of cytokine signalling in immunodeficiency-related non-Hodgkin lymphoma.

Author

Capello, Daniela, Gloghini, Annunziata, Baldanzi, Gianluca, Martini, Maurizio, Deambrogi, Clara, Lucioni, Marco, Piranda, Daniela, Famà, Rosella, Graziani, Andrea, Spina, Michele, Tirelli, Umberto, Paulli, Marco, Larocca, Luigi Maria, Gaidano, Gianluca, Carbone, Antonino, and Sinigaglia, Fabiola

Abstract

We investigated immunodeficiency-related non-Hodgkin lymphoma for the presence of molecular alterations affecting negative regulators of the Janus family protein tyrosine kinase/signal transducer and activator of transcription pathway. Protein tyrosine phosphatase, non-receptor type 6/Src homology 2-containing tyrosine phosphatase-1 epigenetic silencing was recurrent in primary effusion lymphoma (100%), and diffuse large B-cell lymphoma (63%), with a higher prevalence in the non-germinal centre subtype, and was associated with the activation of the Janus family protein tyrosine kinase/signal transducer and activator of transcription 3 pathway. Suppressor of cytokine signalling ( SOCS)1 and SOCS3 epigenetic silencing were occasionally detected, whereas SOCS1 was frequently mutated in diffuse large B-cell lymphoma and polymorphic post-transplant lymphoproliferative disorders, possibly as a cause of aberrant somatic hypermutation. However, the mutation profile of the coding region of the gene was different from that expected from the aberrant somatic hypermutation process, suggesting that, at least in some cases, SOCS1 mutations may have been selected for their functional activity. Copyright © 2012 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results