1. P070 Human leucocyte antigen polymorphism in the modern New Zealand population.
- Author
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Dunckley, Heather, Lopes, Rebecca, Lata, Arishma, Choi, Kai-Luk, Wheeler, Anne, Weston, Patricia, Yik, King Ting, and Behr, Colleen
- Subjects
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ANTIGENS , *POPULATION , *KIDNEY transplantation - Abstract
Highlights from the article: The New Zealand (NZ) population is made up of many ethnic groups, with 88 different ethnicities identified in the national census of 2013, this contributes to human leucocyte antigen (HLA) diversity in New Zealand. HLA alleles of 2832 unrelated individuals typed by next generation sequencing (NGS) were analysed to examine HLA polymorphism in the modern New Zealand population. Twelve alleles not listed as C/WD in 2013 were found to be common (allele frequency >0.001), (DRB3*02:24, DRB3*03:01:03, DQA1*01:04:02, DQB1*05:01:24, DQB1*06:01:05, DPA1*02:01:02, DPA1*02:02:02, DPA1*02:06, DPA1*02:07, DPA1*02:01:04, DPB1*135:01, DPB1*296:01); and 14 alleles were found to be common while only listed as well documented in 2013 (A*02:12, B*15:06, B*40:10:01, B*56:02:01, C*03:02:02, C*04:82, C*07:01:02, C*15:05:02, DRB1*14:08, DRB4*01:03:02, DQA1*01:02:02, DQA1*05:09, DQA1*06:01:01, DPB1*104:01).
- Published
- 2019
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