Search

Your search keyword '"Liu, Jianjun"' showing total 36 results
Start Over "Liu, Jianjun" Journal human molecular genetics
36 results on '"Liu, Jianjun"'

1. Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels

Author

Spracklen, Cassandra N, Chen, Peng, Kim, Young Jin, Wang, Xu, Cai, Hui, Li, Shengxu, Long, Jirong, Wu, Ying, Wang, Ya Xing, Takeuchi, Fumihiko, Wu, Jer-Yuarn, Jung, Keum-Ji, Hu, Cheng, Akiyama, Koichi, Zhang, Yonghong, Moon, Sanghoon, Johnson, Todd A, Li, Huaixing, Dorajoo, Rajkumar, He, Meian, Cannon, Maren E, Roman, Tamara S, Salfati, Elias, Lin, Keng-Hung, Guo, Xiuqing, Sheu, Wayne HH, Absher, Devin, Adair, Linda S, Assimes, Themistocles L, Aung, Tin, Cai, Qiuyin, Chang, Li-Ching, Chen, Chien-Hsiun, Chien, Li-Hsin, Chuang, Lee-Ming, Chuang, Shu-Chun, Du, Shufa, Fan, Qiao, Fann, Cathy SJ, Feranil, Alan B, Friedlander, Yechiel, Gordon-Larsen, Penny, Gu, Dongfeng, Gui, Lixuan, Guo, Zhirong, Heng, Chew-Kiat, Hixson, James, Hou, Xuhong, Hsiung, Chao Agnes, Hu, Yao, Hwang, Mi Yeong, Hwu, Chii-Min, Isono, Masato, Juang, Jyh-Ming Jimmy, Khor, Chiea-Chuen, Kim, Yun Kyoung, Koh, Woon-Puay, Kubo, Michiaki, Lee, I-Te, Lee, Sun-Ju, Lee, Wen-Jane, Liang, Kae-Woei, Lim, Blanche, Lim, Sing-Hui, Liu, Jianjun, Nabika, Toru, Pan, Wen-Harn, Peng, Hao, Quertermous, Thomas, Sabanayagam, Charumathi, Sandow, Kevin, Shi, Jinxiu, Sun, Liang, Tan, Pok Chien, Tan, Shu-Pei, Taylor, Kent D, Teo, Yik-Ying, Toh, Sue-Anne, Tsunoda, Tatsuhiko, van Dam, Rob M, Wang, Aili, Wang, Feijie, Wang, Jie, Bin Wei, Wen, Xiang, Yong-Bing, Yao, Jie, Yuan, Jian-Min, Zhang, Rong, Zhao, Wanting, Chen, Yii-Der Ida, Rich, Stephen S, Rotter, Jerome I, Wang, Tzung-Dau, Wu, Tangchun, Lin, Xu, Han, Bok-Ghee, Tanaka, Toshihiro, Cho, Yoon Shin, Katsuya, Tomohiro, and Jia, Weiping

Subjects
Genetics, Human Genome, Atherosclerosis, 2.1 Biological and endogenous factors, Aetiology, Metabolic and endocrine, Adult, Alleles, Asian People, Cholesterol, Ethnicity, Female, Gene Frequency, Genetic Association Studies, Genome-Wide Association Study, Humans, Linkage Disequilibrium, Lipids, Lipoproteins, HDL, Lipoproteins, LDL, Male, Middle Aged, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Triglycerides, White People, Biological Sciences, Medical and Health Sciences, Genetics & Heredity
Abstract

Large-scale meta-analyses of genome-wide association studies (GWAS) have identified >175 loci associated with fasting cholesterol levels, including total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG). With differences in linkage disequilibrium (LD) structure and allele frequencies between ancestry groups, studies in additional large samples may detect new associations. We conducted staged GWAS meta-analyses in up to 69,414 East Asian individuals from 24 studies with participants from Japan, the Philippines, Korea, China, Singapore, and Taiwan. These meta-analyses identified (P

Published
2017

2. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci

Author

He, Meian, Xu, Min, Zhang, Ben, Liang, Jun, Chen, Peng, Lee, Jong-Young, Johnson, Todd A, Li, Huaixing, Yang, Xiaobo, Dai, Juncheng, Liang, Liming, Gui, Lixuan, Qi, Qibin, Huang, Jinyan, Li, Yanping, Adair, Linda S, Aung, Tin, Cai, Qiuyin, Cheng, Ching-Yu, Cho, Myeong-Chan, Cho, Yoon Shin, Chu, Minjie, Cui, Bin, Gao, Yu-Tang, Go, Min Jin, Gu, Dongfeng, Gu, Weiqiong, Guo, Huan, Hao, Yongchen, Hong, Jie, Hu, Zhibin, Hu, Yanling, Huang, Jianfeng, Hwang, Joo-Yeon, Ikram, Mohammad Kamran, Jin, Guangfu, Kang, Dae-Hee, Khor, Chiea Chuen, Kim, Bong-Jo, Kim, Hung Tae, Kubo, Michiaki, Lee, Jeannette, Lee, Juyoung, Lee, Nanette R, Li, Ruoying, Li, Jun, Liu, JianJun, Longe, Jirong, Lu, Wei, Lu, Xiangfeng, Miao, Xiaoping, Okada, Yukinori, Ong, Rick Twee-Hee, Qiu, Gaokun, Seielstad, Mark, Sim, Xueling, Song, Huaidong, Takeuchi, Fumihiko, Tanaka, Toshihiro, Taylor, Phil R, Wang, Laiyuan, Wang, Weiqing, Wang, Yiqin, Wu, Chen, Wu, Ying, Xiang, Yong-Bing, Yamamoto, Ken, Yang, Handong, Liao, Ming, Yokota, Mitsuhiro, Young, Terri, Zhang, Xiaomin, Kato, Norihiro, Wang, Qing K, Zheng, Wei, Hu, Frank B, Lin, Dongxin, Shen, Hongbing, Teo, Yik Ying, Mo, Zengnan, Wong, Tien Yin, Lin, Xu, Mohlke, Karen L, Ning, Guang, Tsunoda, Tatsuhiko, Han, Bok-Ghee, Shu, Xiao-Ou, Tai, E Shyong, Wu, Tangchun, and Qi, Lu

Subjects
Prevention, Genetics, Human Genome, Aetiology, 2.1 Biological and endogenous factors, Adolescent, Adult, Aged, Aged, 80 and over, Asian People, Body Height, Asia, Eastern, Female, Gene Frequency, Genetic Loci, Genome-Wide Association Study, Humans, Male, Metabolic Networks and Pathways, Middle Aged, Polymorphism, Single Nucleotide, Protein Tyrosine Phosphatases, White People, Young Adult, Biological Sciences, Medical and Health Sciences, Genetics & Heredity
Abstract

Human height is associated with risk of multiple diseases and is profoundly determined by an individual's genetic makeup and shows a high degree of ethnic heterogeneity. Large-scale genome-wide association (GWA) analyses of adult height in Europeans have identified nearly 180 genetic loci. A recent study showed high replicability of results from Europeans-based GWA studies in Asians; however, population-specific loci may exist due to distinct linkage disequilibrium patterns. We carried out a GWA meta-analysis in 93 926 individuals from East Asia. We identified 98 loci, including 17 novel and 81 previously reported loci, associated with height at P < 5 × 10(-8), together explaining 8.89% of phenotypic variance. Among the newly identified variants, 10 are commonly distributed (minor allele frequency, MAF > 5%) in Europeans, with comparable frequencies with in Asians, and 7 single-nucleotide polymorphisms are with low frequency (MAF < 5%) in Europeans. In addition, our data suggest that novel biological pathway such as the protein tyrosine phosphatase family is involved in regulation of height. The findings from this study considerably expand our knowledge of the genetic architecture of human height in Asians.

Published
2015

3. Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk

Author

Painter, Jodie N, O'Mara, Tracy A, Batra, Jyotsna, Cheng, Timothy, Lose, Felicity A, Dennis, Joe, Michailidou, Kyriaki, Tyrer, Jonathan P, Ahmed, Shahana, Ferguson, Kaltin, Healey, Catherine S, Kaufmann, Susanne, Hillman, Kristine M, Walpole, Carina, Moya, Leire, Pollock, Pamela, Jones, Angela, Howarth, Kimberley, Martin, Lynn, Gorman, Maggie, Hodgson, Shirley, De Polanco, Ma Magdalena Echeverry, Sans, Monica, Carracedo, Angel, Castellvi-Bel, Sergi, Rojas-Martinez, Augusto, Santos, Erika, Teixeira, Manuel R, Carvajal-Carmona, Luis, Shu, Xiao-Ou, Long, Jirong, Zheng, Wei, Xiang, Yong-Bing, Montgomery, Grant W, Webb, Penelope M, Scott, Rodney J, McEvoy, Mark, Attia, John, Holliday, Elizabeth, Martin, Nicholas G, Nyholt, Dale R, Henders, Anjali K, Fasching, Peter A, Hein, Alexander, Beckmann, Matthias W, Renner, Stefan P, Dörk, Thilo, Hillemanns, Peter, Dürst, Matthias, Runnebaum, Ingo, Lambrechts, Diether, Coenegrachts, Lieve, Schrauwen, Stefanie, Amant, Frederic, Winterhoff, Boris, Dowdy, Sean C, Goode, Ellen L, Teoman, Attila, Salvesen, Helga B, Trovik, Jone, Njolstad, Tormund S, Werner, Henrica MJ, Ashton, Katie, Proietto, Tony, Otton, Geoffrey, Tzortzatos, Gerasimos, Mints, Miriam, Tham, Emma, Hall, Per, Czene, Kamila, Liu, Jianjun, Li, Jingmei, Hopper, John L, Southey, Melissa C, Ekici, Arif B, Ruebner, Matthias, Johnson, Nicola, Peto, Julian, Burwinkel, Barbara, Marme, Frederik, Brenner, Hermann, Dieffenbach, Aida K, Meindl, Alfons, Brauch, Hiltrud, Lindblom, Annika, Depreeuw, Jeroen, Moisse, Matthieu, Chang-Claude, Jenny, Rudolph, Anja, Couch, Fergus J, Olson, Janet E, Giles, Graham G, Bruinsma, Fiona, Cunningham, Julie M, Fridley, Brooke L, Børresen-Dale, Anne-Lise, Kristensen, Vessela N, Cox, Angela, Swerdlow, Anthony J, and Orr, Nicholas

Subjects
Cancer, Biotechnology, Human Genome, Prevention, Genetics, 2.1 Biological and endogenous factors, Aetiology, Alleles, Case-Control Studies, Cell Line, Tumor, Chromosome Mapping, Computational Biology, Databases, Genetic, Endometrial Neoplasms, Epigenesis, Genetic, Female, Genetic Loci, Genetic Variation, Genome-Wide Association Study, Genotype, Haplotypes, Hepatocyte Nuclear Factor 1-beta, Humans, Linkage Disequilibrium, Polymorphism, Single Nucleotide, Promoter Regions, Genetic, RNA, Messenger, Risk Factors, White People, National Study of Endometrial Cancer Genetics Group, CHIBCHA Consortium, Australian National Endometrial Cancer Study Group, RENDOCAS, Australian Ovarian Cancer Study, GENICA Network, Biological Sciences, Medical and Health Sciences, Genetics & Heredity
Abstract

Common variants in the hepatocyte nuclear factor 1 homeobox B (HNF1B) gene are associated with the risk of Type II diabetes and multiple cancers. Evidence to date indicates that cancer risk may be mediated via genetic or epigenetic effects on HNF1B gene expression. We previously found single-nucleotide polymorphisms (SNPs) at the HNF1B locus to be associated with endometrial cancer, and now report extensive fine-mapping and in silico and laboratory analyses of this locus. Analysis of 1184 genotyped and imputed SNPs in 6608 Caucasian cases and 37 925 controls, and 895 Asian cases and 1968 controls, revealed the best signal of association for SNP rs11263763 (P = 8.4 × 10(-14), odds ratio = 0.86, 95% confidence interval = 0.82-0.89), located within HNF1B intron 1. Haplotype analysis and conditional analyses provide no evidence of further independent endometrial cancer risk variants at this locus. SNP rs11263763 genotype was associated with HNF1B mRNA expression but not with HNF1B methylation in endometrial tumor samples from The Cancer Genome Atlas. Genetic analyses prioritized rs11263763 and four other SNPs in high-to-moderate linkage disequilibrium as the most likely causal SNPs. Three of these SNPs map to the extended HNF1B promoter based on chromatin marks extending from the minimal promoter region. Reporter assays demonstrated that this extended region reduces activity in combination with the minimal HNF1B promoter, and that the minor alleles of rs11263763 or rs8064454 are associated with decreased HNF1B promoter activity. Our findings provide evidence for a single signal associated with endometrial cancer risk at the HNF1B locus, and that risk is likely mediated via altered HNF1B gene expression.

Published
2015

4. Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade.

Author

Purrington, Kristen, Slettedahl, Seth, Bolla, Manjeet, Michailidou, Kyriaki, Czene, Kamila, Nevanlinna, Heli, Bojesen, Stig, Andrulis, Irene, Cox, Angela, Hall, Per, Carpenter, Jane, Yannoukakos, Drakoulis, Haiman, Christopher, Fasching, Peter, Mannermaa, Arto, Winqvist, Robert, Brenner, Hermann, Lindblom, Annika, Chenevix-Trench, Georgia, Benitez, Javier, Swerdlow, Anthony, Kristensen, Vessela, Guénel, Pascal, Meindl, Alfons, Darabi, Hatef, Eriksson, Mikael, Fagerholm, Rainer, Aittomäki, Kristiina, Blomqvist, Carl, Nordestgaard, Børge, Nielsen, Sune, Flyger, Henrik, Wang, Xianshu, Olswold, Curtis, Olson, Janet, Mulligan, Anna, Knight, Julia, Tchatchou, Sandrine, Reed, Malcolm, Cross, Simon, Liu, Jianjun, Li, Jingmei, Humphreys, Keith, Clarke, Christine, Scott, Rodney, Fostira, Florentia, Fountzilas, George, Konstantopoulou, Irene, Henderson, Brian, Schumacher, Fredrick, Le Marchand, Loic, Ekici, Arif, Hartmann, Arndt, Beckmann, Matthias, Hartikainen, Jaana, Kosma, Veli-Matti, Kataja, Vesa, Jukkola-Vuorinen, Arja, Pylkäs, Katri, Kauppila, Saila, Dieffenbach, Aida, Stegmaier, Christa, Arndt, Volker, Margolin, Sara, Balleine, Rosemary, Arias Perez, Jose, Pilar Zamora, M, Menéndez, Primitiva, Ashworth, Alan, Jones, Michael, Orr, Nick, Arveux, Patrick, Kerbrat, Pierre, Truong, Thérèse, Bugert, Peter, Toland, Amanda, Ambrosone, Christine, Labrèche, France, Goldberg, Mark, Dumont, Martine, Ziogas, Argyrios, Lee, Eunjung, Dite, Gillian, Apicella, Carmel, Southey, Melissa, Long, Jirong, Shrubsole, Martha, Deming-Halverson, Sandra, Ficarazzi, Filomena, Barile, Monica, Peterlongo, Paolo, Durda, Katarzyna, Jaworska-Bieniek, Katarzyna, Tollenaar, Robert, Seynaeve, Caroline, Brüning, Thomas, Ko, Yon-Dschun, Van Deurzen, Carolien, Martens, John, and Kriege, Mieke

Subjects
Breast Neoplasms, Carrier Proteins, Case-Control Studies, Female, Genetic Variation, Haplotypes, Humans, Neoplasm Staging, Polymorphism, Single Nucleotide, Receptor, Fibroblast Growth Factor, Type 2, Risk Factors, Tumor Suppressor Proteins
Abstract

Mitotic index is an important component of histologic grade and has an etiologic role in breast tumorigenesis. Several small candidate gene studies have reported associations between variation in mitotic genes and breast cancer risk. We measured associations between 2156 single nucleotide polymorphisms (SNPs) from 194 mitotic genes and breast cancer risk, overall and by histologic grade, in the Breast Cancer Association Consortium (BCAC) iCOGS study (n = 39 067 cases; n = 42 106 controls). SNPs in TACC2 [rs17550038: odds ratio (OR) = 1.24, 95% confidence interval (CI) 1.16-1.33, P = 4.2 × 10(-10)) and EIF3H (rs799890: OR = 1.07, 95% CI 1.04-1.11, P = 8.7 × 10(-6)) were significantly associated with risk of low-grade breast cancer. The TACC2 signal was retained (rs17550038: OR = 1.15, 95% CI 1.07-1.23, P = 7.9 × 10(-5)) after adjustment for breast cancer risk SNPs in the nearby FGFR2 gene, suggesting that TACC2 is a novel, independent genome-wide significant genetic risk locus for low-grade breast cancer. While no SNPs were individually associated with high-grade disease, a pathway-level gene set analysis showed that variation across the 194 mitotic genes was associated with high-grade breast cancer risk (P = 2.1 × 10(-3)). These observations will provide insight into the contribution of mitotic defects to histological grade and the etiology of breast cancer.

Published
2014

5. A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11

Author

Siddiq, Afshan, Couch, Fergus J, Chen, Gary K, Lindström, Sara, Eccles, Diana, Millikan, Robert C, Michailidou, Kyriaki, Stram, Daniel O, Beckmann, Lars, Rhie, Suhn Kyong, Ambrosone, Christine B, Aittomäki, Kristiina, Amiano, Pilar, Apicella, Carmel, Investigators, Australian Breast Cancer Tissue Bank, Baglietto, Laura, Bandera, Elisa V, Beckmann, Matthias W, Berg, Christine D, Bernstein, Leslie, Blomqvist, Carl, Brauch, Hiltrud, Brinton, Louise, Bui, Quang M, Buring, Julie E, Buys, Saundra S, Campa, Daniele, Carpenter, Jane E, Chasman, Daniel I, Chang-Claude, Jenny, Chen, Constance, Clavel-Chapelon, Françoise, Cox, Angela, Cross, Simon S, Czene, Kamila, Deming, Sandra L, Diasio, Robert B, Diver, W Ryan, Dunning, Alison M, Durcan, Lorraine, Ekici, Arif B, Fasching, Peter A, Study, Familial Breast Cancer, Feigelson, Heather Spencer, Fejerman, Laura, Figueroa, Jonine D, Fletcher, Olivia, Flesch-Janys, Dieter, Gaudet, Mia M, Consortium, The GENICA, Gerty, Susan M, Rodriguez-Gil, Jorge L, Giles, Graham G, van Gils, Carla H, Godwin, Andrew K, Graham, Nikki, Greco, Dario, Hall, Per, Hankinson, Susan E, Hartmann, Arndt, Hein, Rebecca, Heinz, Judith, Hoover, Robert N, Hopper, John L, Hu, Jennifer J, Huntsman, Scott, Ingles, Sue A, Irwanto, Astrid, Isaacs, Claudine, Jacobs, Kevin B, John, Esther M, Justenhoven, Christina, Kaaks, Rudolf, Kolonel, Laurence N, Coetzee, Gerhard A, Lathrop, Mark, Le Marchand, Loic, Lee, Adam M, Lee, I-Min, Lesnick, Timothy, Lichtner, Peter, Liu, Jianjun, Lund, Eiliv, Makalic, Enes, Martin, Nicholas G, McLean, Catriona A, Meijers-Heijboer, Hanne, Meindl, Alfons, Miron, Penelope, Monroe, Kristine R, Montgomery, Grant W, Müller-Myhsok, Bertram, Nickels, Stefan, Nyante, Sarah J, Olswold, Curtis, Overvad, Kim, Palli, Domenico, Park, Daniel J, Palmer, Julie R, and Pathak, Harsh

Subjects
Biological Sciences, Genetics, Clinical Research, Aging, Human Genome, Breast Cancer, Cancer, Aetiology, 2.1 Biological and endogenous factors, Breast Neoplasms, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Polymorphism, Single Nucleotide, Receptors, Estrogen, Australian Breast Cancer Tissue Bank Investigators, Familial Breast Cancer Study, GENICA Consortium, Medical and Health Sciences, Genetics & Heredity
Abstract

Genome-wide association studies (GWAS) of breast cancer defined by hormone receptor status have revealed loci contributing to susceptibility of estrogen receptor (ER)-negative subtypes. To identify additional genetic variants for ER-negative breast cancer, we conducted the largest meta-analysis of ER-negative disease to date, comprising 4754 ER-negative cases and 31 663 controls from three GWAS: NCI Breast and Prostate Cancer Cohort Consortium (BPC3) (2188 ER-negative cases; 25 519 controls of European ancestry), Triple Negative Breast Cancer Consortium (TNBCC) (1562 triple negative cases; 3399 controls of European ancestry) and African American Breast Cancer Consortium (AABC) (1004 ER-negative cases; 2745 controls). We performed in silico replication of 86 SNPs at P ≤ 1 × 10(-5) in an additional 11 209 breast cancer cases (946 with ER-negative disease) and 16 057 controls of Japanese, Latino and European ancestry. We identified two novel loci for breast cancer at 20q11 and 6q14. SNP rs2284378 at 20q11 was associated with ER-negative breast cancer (combined two-stage OR = 1.16; P = 1.1 × 10(-8)) but showed a weaker association with overall breast cancer (OR = 1.08, P = 1.3 × 10(-6)) based on 17 869 cases and 43 745 controls and no association with ER-positive disease (OR = 1.01, P = 0.67) based on 9965 cases and 22 902 controls. Similarly, rs17530068 at 6q14 was associated with breast cancer (OR = 1.12; P = 1.1 × 10(-9)), and with both ER-positive (OR = 1.09; P = 1.5 × 10(-5)) and ER-negative (OR = 1.16, P = 2.5 × 10(-7)) disease. We also confirmed three known loci associated with ER-negative (19p13) and both ER-negative and ER-positive breast cancer (6q25 and 12p11). Our results highlight the value of large-scale collaborative studies to identify novel breast cancer risk loci.

Published
2012

6. Association of ESR1 gene tagging SNPs with breast cancer risk

Author

Dunning, Alison M, Healey, Catherine S, Baynes, Caroline, Maia, Ana-Teresa, Scollen, Serena, Vega, Ana, Rodríguez, Raquel, Barbosa-Morais, Nuno L, Ponder, Bruce AJ, Low, Yen-Ling, Bingham, Sheila, Haiman, Christopher A, Le Marchand, Loic, Broeks, Annegien, Schmidt, Marjanka K, Hopper, John, Southey, Melissa, Beckmann, Matthias W, Fasching, Peter A, Peto, Julian, Johnson, Nichola, Bojesen, Stig E, Nordestgaard, Børge, Milne, Roger L, Benitez, Javier, Hamann, Ute, Ko, Yon, Schmutzler, Rita K, Burwinkel, Barbara, Schürmann, Peter, Dörk, Thilo, Heikkinen, Tuomas, Nevanlinna, Heli, Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Kosma, Veli-Matti, Chen, Xiaoqing, Spurdle, Amanda, Change-Claude, Jenny, Flesch-Janys, Dieter, Couch, Fergus J, Olson, Janet E, Severi, Gianluca, Baglietto, Laura, Børresen-Dale, Anne-Lise, Kristensen, Vessela, Hunter, David J, Hankinson, Susan E, Devilee, Peter, Vreeswijk, Maaike, Lissowska, Jolanta, Brinton, Louise, Liu, Jianjun, Hall, Per, Kang, Daehee, Yoo, Keun-Young, Shen, Chen-Yang, Yu, Jyh-Cherng, Anton-Culver, Hoda, Ziogoas, Argyrios, Sigurdson, Alice, Struewing, Jeff, Easton, Douglas F, Garcia-Closas, Montserrat, Humphreys, Manjeet K, Morrison, Jonathan, Pharoah, Paul DP, Pooley, Karen A, and Chenevix-Trench, Georgia

Subjects
Genetics, Cancer, Breast Cancer, Prevention, Clinical Research, 2.1 Biological and endogenous factors, Aetiology, Breast Neoplasms, Estrogen Receptor alpha, Female, Genetic Predisposition to Disease, Haplotypes, Humans, Neoplasm Staging, Polymorphism, Single Nucleotide, RNA, Neoplasm, SEARCH, EPIC, MEC, ABCS, ABCFS, BBCC, BBCS, CGPS, CNIO-BCS, GENICA, GC-HBOC, HABCS, HEBCS, KARBAC, KBCS, kConFab and the AOCS Management Group, MARIE, for MCBCS, MCCS, NBCS, NHS, ORIGO, PBCS, SASBAC, SEBCS, TWBCS, UCIBCS, USRTS, BCAC, Biological Sciences, Medical and Health Sciences, Genetics & Heredity
Abstract

We have conducted a three-stage, comprehensive single nucleotide polymorphism (SNP)-tagging association study of ESR1 gene variants (SNPs) in more than 55,000 breast cancer cases and controls from studies within the Breast Cancer Association Consortium (BCAC). No large risks or highly significant associations were revealed. SNP rs3020314, tagging a region of ESR1 intron 4, is associated with an increase in breast cancer susceptibility with a dominant mode of action in European populations. Carriers of the c-allele have an odds ratio (OR) of 1.05 [95% Confidence Intervals (CI) 1.02-1.09] relative to t-allele homozygotes, P = 0.004. There is significant heterogeneity between studies, P = 0.002. The increased risk appears largely confined to oestrogen receptor-positive tumour risk. The region tagged by SNP rs3020314 contains sequence that is more highly conserved across mammalian species than the rest of intron 4, and it may subtly alter the ratio of two mRNA splice forms.

Published
2009

7. Identification of shared loci associated with both Crohn’s disease and leprosy in East Asians

Author

Jung, Seulgi, primary, Park, Dohoon, additional, Lee, Ho-Su, additional, Kim, Yongjae, additional, Baek, Jiwon, additional, Hwang, Sung Wook, additional, Park, Sang Hyoung, additional, Yang, Suk-Kyun, additional, Ye, Byong Duk, additional, Han, Buhm, additional, Sun, Yonghu, additional, Liu, Hong, additional, Zhang, Furen, additional, Liu, Jianjun, additional, and Song, Kyuyoung, additional

Published
2022
Full Text
View/download PDF

8. Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations

Author

Seow, Wei Jie, Matsuo, Keitaro, Hsiung, Chao Agnes, Shiraishi, Kouya, Song, Minsun, Kim, Hee Nam, Wong, Maria Pik, Hong, Yun-Chul, Hosgood, H. Dean, III, Wang, Zhaoming, Chang, I-Shou, Wang, Jiu-Cun, Chatterjee, Nilanjan, Tucker, Margaret, Wei, Hu, Mitsudomi, Tetsuya, Zheng, Wei, Kim, Jin Hee, Zhou, Baosen, Caporaso, Neil E., Albanes, Demetrius, Shin, Min-Ho, Chung, Lap Ping, An, She-Juan, Wang, Ping, Zheng, Hong, Yatabe, Yasushi, Zhang, Xu-Chao, Kim, Young Tae, Shu, Xiao-Ou, Kim, Young-Chul, Bassig, Bryan A., Chang, Jiang, Ho, James Chung Man, Ji, Bu-Tian, Kubo, Michiaki, Daigo, Yataro, Ito, Hidemi, Momozawa, Yukihide, Ashikawa, Kyota, Kamatani, Yoichiro, Honda, Takayuki, Sakamoto, Hiromi, Kunitoh, Hideo, Tsuta, Koji, Watanabe, Shun-Ichi, Nokihara, Hiroshi, Miyagi, Yohei, Nakayama, Haruhiko, Matsumoto, Shingo, Tsuboi, Masahiro, Goto, Koichi, Yin, Zhihua, Shi, Jianxin, Takahashi, Atsushi, Goto, Akiteru, Minamiya, Yoshihiro, Shimizu, Kimihiro, Tanaka, Kazumi, Wu, Tangchun, Wei, Fusheng, Wong, Jason Y.Y., Matsuda, Fumihiko, Su, Jian, Kim, Yeul Hong, Oh, In-Jae, Song, Fengju, Lee, Victor Ho Fun, Su, Wu-Chou, Chen, Yuh-Min, Chang, Gee-Chen, Chen, Kuan-Yu, Huang, Ming-Shyan, Yang, Pan-Chyr, Lin, Hsien-Chih, Xiang, Yong-Bing, Seow, Adeline, Park, Jae Yong, Kweon, Sun-Seog, Chen, Chien-Jen, Li, Haixin, Gao, Yu-Tang, Wu, Chen, Qian, Biyun, Lu, Daru, Liu, Jianjun, Jeon, Hyo-Sung, Hsiao, Chin-Fu, Sung, Jae Sook, Tsai, Ying-Huang, Jung, Yoo Jin, Guo, Huan, Hu, Zhibin, Wang, Wen-Chang, Chung, Charles C., Lawrence, Charles, Burdett, Laurie, Yeager, Meredith, Jacobs, Kevin B., Hutchinson, Amy, Berndt, Sonja I., He, Xingzhou, Wu, Wei, Wang, Junwen, Li, Yuqing, Choi, Jin Eun, Park, Kyong Hwa, Sung, Sook Whan, Liu, Li, Kang, Chang Hyun, Hu, Lingmin, Chen, Chung-Hsing, Yang, Tsung-Ying, Xu, Jun, Guan, Peng, Tan, Wen, Wang, Chih-Liang, Sihoe, Alan Dart Loon, Chen, Ying, Choi, Yi Young, Hung, Jen-Yu, Kim, Jun Suk, Yoon, Ho-Il, Cai, Qiuyin, Lin, Chien-Chung, Park, In Kyu, Xu, Ping, Dong, Jing, Kim, Christopher, He, Qincheng, Perng, Reury-Perng, Chen, Chih-Yi, Vermeulen, Roel, Wu, Junjie, Lim, Wei-Yen, Chen, Kun-Chieh, Chan, John K.C., Chu, Minjie, Li, Yao-Jen, Li, Jihua, Chen, Hongyan, Yu, Chong-Jen, Jin, Li, Lo, Yen-Li, Chen, Ying-Hsiang, Fraumeni, Joseph F., Jr, Liu, Jie, Yamaji, Taiki, Yang, Yang, Hicks, Belynda, Wyatt, Kathleen, Li, Shengchao A., Dai, Juncheng, Ma, Hongxia, Jin, Guangfu, Song, Bao, Wang, Zhehai, Cheng, Sensen, Li, Xuelian, Ren, Yangwu, Cui, Ping, Iwasaki, Motoki, Shimazu, Taichi, Tsugane, Shoichiro, Zhu, Junjie, Jiang, Gening, Fei, Ke, Wu, Guoping, Chien, Li-Hsin, Chen, Hui-Ling, Su, Yu-Chun, Tsai, Fang-Yu, Chen, Yi-Song, Yu, Jinming, Stevens, Victoria L., Laird-Offringa, Ite A., Marconett, Crystal N., Lin, Dongxin, Chen, Kexin, Wu, Yi-Long, Landi, Maria Teresa, Shen, Hongbing, Rothman, Nathaniel, Kohno, Takashi, Chanock, Stephen J., and Lan, Qing

Published
2017
Full Text
View/download PDF

9. Genome-wide association study of Parkinson’s disease in East Asians

Author

Foo, Jia Nee, Tan, Louis C., Irwan, Ishak D., Au, Wing-Lok, Low, Hui Qi, Prakash, Kumar-M., Ahmad-Annuar, Azlina, Bei, Jinxin, Chan, Anne YY, Chen, Chiung Mei, Chen, Yi-Chun, Chung, Sun Ju, Deng, Hao, Lim, Shen-Yang, Mok, Vincent, Pang, Hao, Pei, Zhong, Peng, Rong, Shang, Hui-Fang, Song, Kyuyoung, Tan, Ai Huey, Wu, Yih-Ru, Aung, Tin, Cheng, Ching-Yu, Chew, Fook Tim, Chew, Soo-Hong, Chong, Siow-Ann, Ebstein, Richard P., Lee, Jimmy, Saw, Seang-Mei, Seow, Adeline, Subramaniam, Mythily, Tai, E-Shyong, Vithana, Eranga N., Wong, Tien-Yin, Heng, Khai Koon, Meah, Wee-Yang, Khor, Chiea Chuen, Liu, Hong, Zhang, Furen, Liu, Jianjun, and Tan, Eng-King

Published
2017
Full Text
View/download PDF

10. Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

Author

Wang, Zhaoming, Seow, Wei Jie, Shiraishi, Kouya, Hsiung, Chao A., Matsuo, Keitaro, Liu, Jie, Chen, Kexin, Yamji, Taiki, Yang, Yang, Chang, I-Shou, Wu, Chen, Hong, Yun-Chul, Burdett, Laurie, Wyatt, Kathleen, Chung, Charles C., Li, Shengchao A., Yeager, Meredith, Hutchinson, Amy, Hu, Wei, Caporaso, Neil, Landi, Maria T., Chatterjee, Nilanjan, Song, Minsun, Fraumeni, Joseph F., Jr, Kohno, Takashi, Yokota, Jun, Kunitoh, Hideo, Ashikawa, Kyota, Momozawa, Yukihide, Daigo, Yataro, Mitsudomi, Tetsuya, Yatabe, Yasushi, Hida, Toyoaki, Hu, Zhibin, Dai, Juncheng, Ma, Hongxia, Jin, Guangfu, Song, Bao, Wang, Zhehai, Cheng, Sensen, Yin, Zhihua, Li, Xuelian, Ren, Yangwu, Guan, Peng, Chang, Jiang, Tan, Wen, Chen, Chien-Jen, Chang, Gee-Chen, Tsai, Ying-Huang, Su, Wu-Chou, Chen, Kuan-Yu, Huang, Ming-Shyan, Chen, Yuh-Min, Zheng, Hong, Li, Haixin, Cui, Ping, Guo, Huan, Xu, Ping, Liu, Li, Iwasaki, Motoki, Shimazu, Taichi, Tsugane, Shoichiro, Zhu, Junjie, Jiang, Gening, Fei, Ke, Park, Jae Yong, Kim, Yeul Hong, Sung, Jae Sook, Park, Kyong Hwa, Kim, Young Tae, Jung, Yoo Jin, Kang, Chang Hyun, Park, In Kyu, Kim, Hee Nam, Jeon, Hyo-Sung, Choi, Jin Eun, Choi, Yi Young, Kim, Jin Hee, Oh, In-Jae, Kim, Young-Chul, Sung, Sook Whan, Kim, Jun Suk, Yoon, Ho-Il, Kweon, Sun-Seog, Shin, Min-Ho, Seow, Adeline, Chen, Ying, Lim, Wei-Yen, Liu, Jianjun, Wong, Maria Pik, Lee, Victor Ho Fun, Bassig, Bryan A., Tucker, Margaret, Berndt, Sonja I., Chow, Wong-Ho, Ji, Bu-Tian, Wang, Junwen, Xu, Jun, Sihoe, Alan Dart Loon, Ho, James C.M., Chan, John K.C., Wang, Jiu-Cun, Lu, Daru, Zhao, Xueying, Zhao, Zhenhong, Wu, Junjie, Chen, Hongyan, Jin, Li, Wei, Fusheng, Wu, Guoping, An, She-Juan, Zhang, Xu-Chao, Su, Jian, Wu, Yi-Long, Gao, Yu-Tang, Xiang, Yong-Bing, He, Xingzhou, Li, Jihua, Zheng, Wei, Shu, Xiao-Ou, Cai, Qiuyin, Klein, Robert, Pao, William, Lawrence, Charles, Hosgood, H. Dean, III, Hsiao, Chin-Fu, Chien, Li-Hsin, Chen, Ying-Hsiang, Chen, Chung-Hsing, Wang, Wen-Chang, Chen, Chih-Yi, Wang, Chih-Liang, Yu, Chong-Jen, Chen, Hui-Ling, Su, Yu-Chun, Tsai, Fang-Yu, Chen, Yi-Song, Li, Yao-Jen, Yang, Tsung-Ying, Lin, Chien-Chung, Yang, Pan-Chyr, Wu, Tangchun, Lin, Dongxin, Zhou, Baosen, Yu, Jinming, Shen, Hongbing, Kubo, Michiaki, Chanock, Stephen J., Rothman, Nathaniel, and Lan, Qing

Published
2016
Full Text
View/download PDF

11. A common variant near TGFBR3 is associated with primary open angle glaucoma

Author

Li, Zheng, Allingham, R. Rand, Nakano, Masakazu, Jia, Liyun, Chen, Yuhong, Ikeda, Yoko, Mani, Baskaran, Chen, Li-Jia, Kee, Changwon, Garway-Heath, David F., Sripriya, Sarangapani, Fuse, Nobuo, Abu-Amero, Khaled K., Huang, Chukai, Namburi, Prasanthi, Burdon, Kathryn, Perera, Shamira A., Gharahkhani, Puya, Lin, Ying, Ueno, Morio, Ozaki, Mineo, Mizoguchi, Takanori, Krishnadas, Subbiah Ramasamy, Osman, Essam A., Lee, Mei Chin, Chan, Anita S.Y., Tajudin, Liza-Sharmini A., Do, Tan, Goncalves, Aurelien, Reynier, Pascal, Zhang, Hong, Bourne, Rupert, Goh, David, Broadway, David, Husain, Rahat, Negi, Anil K., Su, Daniel H, Ho, Ching-Lin, Blanco, Augusto Azuara, Leung, Christopher K.S., Wong, Tina T., Yakub, Azhany, Liu, Yutao, Nongpiur, Monisha E., Han, Jong Chul, Hon, Do Nhu, Shantha, Balekudaru, Zhao, Bowen, Sang, Jinghong, Zhang, NiHong, Sato, Ryuichi, Yoshii, Kengo, Panda-Jonas, Songhomita, Ashley Koch, Allison E., Herndon, Leon W., Moroi, Sayoko E., Challa, Pratap, Foo, Jia Nee, Bei, Jin-Xin, Zeng, Yi-Xin, Simmons, Cameron P., Bich Chau, Tran Nguyen, Sharmila, Philomenadin Ferdinamarie, Chew, Merwyn, Lim, Blanche, Tam, Pansy O.S., Chua, Elaine, Ng, Xiao Yu, Yong, Victor H.K., Chong, Yaan Fun, Meah, Wee Yang, Vijayan, Saravanan, Seongsoo, Sohn, Xu, Wang, Teo, Yik Ying, Cooke Bailey, Jessica N., Kang, Jae H., Haines, Jonathan L., Cheng, Ching Yu, Saw, Seang-Mei, Tai, E-Shyong, Richards, Julia E., Ritch, Robert, Gaasterland, Douglas E., Pasquale, Louis R., Liu, Jianjun, Jonas, Jost B., Milea, Dan, George, Ronnie, Al-Obeidan, Saleh A., Mori, Kazuhiko, Macgregor, Stuart, Hewitt, Alex W., Girkin, Christopher A., Zhang, Mingzhi, Sundaresan, Periasamy, Vijaya, Lingam, Mackey, David A., Wong, Tien Yin, Craig, Jamie E., Sun, Xinghuai, Kinoshita, Shigeru, Wiggs, Janey L., Khor, Chiea-Chuen, Yang, Zhenglin, Pang, Chi Pui, Wang, Ningli, Hauser, Michael A., Tashiro, Kei, Aung, Tin, and Vithana, Eranga N.

Published
2015
Full Text
View/download PDF

12. Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2

Author

Orr, Nick, Dudbridge, Frank, Dryden, Nicola, Maguire, Sarah, Novo, Daniela, Perrakis, Eleni, Johnson, Nichola, Ghoussaini, Maya, Hopper, John L., Southey, Melissa C., Apicella, Carmel, Stone, Jennifer, Schmidt, Marjanka K., Broeks, Annegien, Vanʼt Veer, Laura J., Hogervorst, Frans B., Fasching, Peter A., Haeberle, Lothar, Ekici, Arif B., Beckmann, Matthias W., Gibson, Lorna, Aitken, Zoe, Warren, Helen, Sawyer, Elinor, Tomlinson, Ian, Kerin, Michael J., Miller, Nicola, Burwinkel, Barbara, Marme, Frederik, Schneeweiss, Andreas, Sohn, Chistof, Guénel, Pascal, Truong, Thérèse, Cordina-Duverger, Emilie, Sanchez, Marie, Bojesen, Stig E., Nordestgaard, Børge G., Nielsen, Sune F., Flyger, Henrik, Benitez, Javier, Zamora, Maria Pilar, Arias Perez, Jose Ignacio, Menéndez, Primitiva, Anton-Culver, Hoda, Neuhausen, Susan L., Brenner, Hermann, Dieffenbach, Aida Karina, Arndt, Volker, Stegmaier, Christa, Hamann, Ute, Brauch, Hiltrud, Justenhoven, Christina, Brüning, Thomas, Ko, Yon-Dschun, Nevanlinna, Heli, Aittomäki, Kristiina, Blomqvist, Carl, Khan, Sofia, Bogdanova, Natalia, Dörk, Thilo, Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M., Chenevix-Trench, Georgia, Beesley, Jonathan, Lambrechts, Diether, Moisse, Matthieu, Floris, Guiseppe, Beuselinck, Benoit, Chang-Claude, Jenny, Rudolph, Anja, Seibold, Petra, Flesch-Janys, Dieter, Radice, Paolo, Peterlongo, Paolo, Peissel, Bernard, Pensotti, Valeria, Couch, Fergus J., Olson, Janet E., Slettedahl, Seth, Vachon, Celine, Giles, Graham G., Milne, Roger L., McLean, Catriona, Haiman, Christopher A., Henderson, Brian E., Schumacher, Fredrick, Le Marchand, Loic, Simard, Jacques, Goldberg, Mark S., Labrèche, France, Dumont, Martine, Kristensen, Vessela, Alnæs, Grethe Grenaker, Nord, Silje, Borresen-Dale, Anne-Lise, Zheng, Wei, Deming-Halverson, Sandra, Shrubsole, Martha, Long, Jirong, Winqvist, Robert, Pylkäs, Katri, Jukkola-Vuorinen, Arja, Grip, Mervi, Andrulis, Irene L., Knight, Julia A., Glendon, Gord, Tchatchou, Sandrine, Devilee, Peter, Tollenaar, Robertus A. E. M., Seynaeve, Caroline M., Van Asperen, Christi J., Garcia-Closas, Montserrat, Figueroa, Jonine, Chanock, Stephen J., Lissowska, Jolanta, Czene, Kamila, Darabi, Hatef, Eriksson, Mikael, Klevebring, Daniel, Hooning, Maartje J., Hollestelle, Antoinette, van Deurzen, Carolien H. M., Kriege, Mieke, Hall, Per, Li, Jingmei, Liu, Jianjun, Humphreys, Keith, Cox, Angela, Cross, Simon S., Reed, Malcolm W. R., Pharoah, Paul D. P., Dunning, Alison M., Shah, Mitul, Perkins, Barbara J., Jakubowska, Anna, Lubinski, Jan, Jaworska-Bieniek, Katarzyna, Durda, Katarzyna, Ashworth, Alan, Swerdlow, Anthony, Jones, Michael, Schoemaker, Minouk J., Meindl, Alfons, Schmutzler, Rita K., Olswold, Curtis, Slager, Susan, Toland, Amanda E., Yannoukakos, Drakoulis, Muir, Kenneth, Lophatananon, Artitaya, Stewart-Brown, Sarah, Siriwanarangsan, Pornthep, Matsuo, Keitaro, Ito, Hidema, Iwata, Hiroji, Ishiguro, Junko, Wu, Anna H., Tseng, Chiu-chen, Van Den Berg, David, Stram, Daniel O., Teo, Soo Hwang, Yip, Cheng Har, Kang, Peter, Ikram, Mohammad Kamran, Shu, Xiao-Ou, Lu, Wei, Gao, Yu-Tang, Cai, Hui, Kang, Daehee, Choi, Ji-Yeob, Park, Sue K., Noh, Dong-Young, Hartman, Mikael, Miao, Hui, Lim, Wei Yen, Lee, Soo Chin, Sangrajrang, Suleeporn, Gaborieau, Valerie, Brennan, Paul, Mckay, James, Wu, Pei-Ei, Hou, Ming-Feng, Yu, Jyh-Cherng, Shen, Chen-Yang, Blot, William, Cai, Qiuyin, Signorello, Lisa B., Luccarini, Craig, Bayes, Caroline, Ahmed, Shahana, Maranian, Mel, Healey, Catherine S., González-Neira, Anna, Pita, Guillermo, Alonso, M. Rosario, Álvarez, Nuria, Herrero, Daniel, Tessier, Daniel C., Vincent, Daniel, Bacot, Francois, Hunter, David J., Lindstrom, Sara, Dennis, Joe, Michailidou, Kyriaki, Bolla, Manjeet K., Easton, Douglas F., dos Santos Silva, Isabel, Fletcher, Olivia, and Peto, Julian

Published
2015
Full Text
View/download PDF

13. Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk

Author

Lin, Wei-Yu, Camp, Nicola J., Ghoussaini, Maya, Beesley, Jonathan, Michailidou, Kyriaki, Hopper, John L., Apicella, Carmel, Southey, Melissa C., Stone, Jennifer, Schmidt, Marjanka K., Broeks, Annegien, Vanʼt Veer, Laura J., Th Rutgers, Emiel J., Muir, Kenneth, Lophatananon, Artitaya, Stewart-Brown, Sarah, Siriwanarangsan, Pornthep, Fasching, Peter A., Haeberle, Lothar, Ekici, Arif B., Beckmann, Matthias W., Peto, Julian, Dos-Santos-Silva, Isabel, Fletcher, Olivia, Johnson, Nichola, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Sawyer, Elinor J., Cheng, Timothy, Tomlinson, Ian, Kerin, Michael J., Miller, Nicola, Marmé, Frederik, Surowy, Harald M., Burwinkel, Barbara, Guénel, Pascal, Truong, Thérèse, Menegaux, Florence, Mulot, Claire, Bojesen, Stig E., Nordestgaard, Børge G., Nielsen, Sune F., Flyger, Henrik, Benitez, Javier, Zamora, M. Pilar, Arias Perez, Jose Ignacio, Menéndez, Primitiva, González-Neira, Anna, Pita, Guillermo, Alonso, M. Rosario, Álvarez, Nuria, Herrero, Daniel, Anton-Culver, Hoda, Brenner, Hermann, Dieffenbach, Aida Karina, Arndt, Volker, Stegmaier, Christa, Meindl, Alfons, Lichtner, Peter, Schmutzler, Rita K., Müller-Myhsok, Bertram, Brauch, Hiltrud, Brüning, Thomas, Ko, Yon-Dschun, Tessier, Daniel C., Vincent, Daniel, Bacot, Francois, Nevanlinna, Heli, Aittomäki, Kristiina, Blomqvist, Carl, Khan, Sofia, Matsuo, Keitaro, Ito, Hidemi, Iwata, Hiroji, Horio, Akiyo, Bogdanova, Natalia V., Antonenkova, Natalia N., Dörk, Thilo, Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M., Wu, Anna H., Tseng, Chiu-Chen, Van Den Berg, David, Stram, Daniel O., Neven, Patrick, Wauters, Els, Wildiers, Hans, Lambrechts, Diether, Chang-Claude, Jenny, Rudolph, Anja, Seibold, Petra, Flesch-Janys, Dieter, Radice, Paolo, Peterlongo, Paolo, Manoukian, Siranoush, Bonanni, Bernardo, Couch, Fergus J., Wang, Xianshu, Vachon, Celine, Purrington, Kristen, Giles, Graham G., Milne, Roger L., Mclean, Catriona, Haiman, Christopher A., Henderson, Brian E., Schumacher, Fredrick, Le Marchand, Loic, Simard, Jacques, Goldberg, Mark S., Labrèche, France, Dumont, Martine, Teo, Soo Hwang, Yip, Cheng Har, Hassan, Norhashimah, Vithana, Eranga Nishanthie, Kristensen, Vessela, Zheng, Wei, Deming-Halverson, Sandra, Shrubsole, Martha J., Long, Jirong, Winqvist, Robert, Pylkäs, Katri, Jukkola-Vuorinen, Arja, Kauppila, Saila, Andrulis, Irene L., Knight, Julia A., Glendon, Gord, Tchatchou, Sandrine, Devilee, Peter, Tollenaar, Robert A.E.M., Seynaeve, Caroline, Van Asperen, Christi J., García-Closas, Montserrat, Figueroa, Jonine, Lissowska, Jolanta, Brinton, Louise, Czene, Kamila, Darabi, Hatef, Eriksson, Mikael, Brand, Judith S., Hooning, Maartje J., Hollestelle, Antoinette, Van Den Ouweland, Ans M.W., Jager, Agnes, Li, Jingmei, Liu, Jianjun, Humphreys, Keith, Shu, Xiao-Ou, Lu, Wei, Gao, Yu-Tang, Cai, Hui, Cross, Simon S., Reed, Malcolm W. R., Blot, William, Signorello, Lisa B., Cai, Qiuyin, Pharoah, Paul D.P., Perkins, Barbara, Shah, Mitul, Blows, Fiona M., Kang, Daehee, Yoo, Keun-Young, Noh, Dong-Young, Hartman, Mikael, Miao, Hui, Chia, Kee Seng, Putti, Thomas Choudary, Hamann, Ute, Luccarini, Craig, Baynes, Caroline, Ahmed, Shahana, Maranian, Mel, Healey, Catherine S., Jakubowska, Anna, Lubinski, Jan, Jaworska-Bieniek, Katarzyna, Durda, Katarzyna, Sangrajrang, Suleeporn, Gaborieau, Valerie, Brennan, Paul, Mckay, James, Slager, Susan, Toland, Amanda E., Yannoukakos, Drakoulis, Shen, Chen-Yang, Hsiung, Chia-Ni, Wu, Pei-Ei, Ding, Shian-ling, Ashworth, Alan, Jones, Michael, Orr, Nick, Swerdlow, Anthony J, Tsimiklis, Helen, Makalic, Enes, Schmidt, Daniel F., Bui, Quang M., Chanock, Stephen J., Hunter, David J., Hein, Rebecca, Dahmen, Norbert, Beckmann, Lars, Aaltonen, Kirsimari, Muranen, Taru A., Heikkinen, Tuomas, Irwanto, Astrid, Rahman, Nazneen, Turnbull, Clare A., Waisfisz, Quinten, Meijers-Heijboer, Hanne E. J., Adank, Muriel A., Van Der Luijt, Rob B., Hall, Per, Chenevix-Trench, Georgia, Dunning, Alison, Easton, Douglas F., and Cox, Angela

Published
2015
Full Text
View/download PDF

14. Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

Author

Wang, Zhaoming, Zhu, Bin, Zhang, Mingfeng, Parikh, Hemang, Jia, Jinping, Chung, Charles C., Sampson, Joshua N., Hoskins, Jason W., Hutchinson, Amy, Burdette, Laurie, Ibrahim, Abdisamad, Hautman, Christopher, Raj, Preethi S., Abnet, Christian C., Adjei, Andrew A., Ahlbom, Anders, Albanes, Demetrius, Allen, Naomi E., Ambrosone, Christine B., Aldrich, Melinda, Amiano, Pilar, Amos, Christopher, Andersson, Ulrika, Andriole, Gerald, Jr, Andrulis, Irene L., Arici, Cecilia, Arslan, Alan A., Austin, Melissa A., Baris, Dalsu, Barkauskas, Donald A., Bassig, Bryan A., Beane Freeman, Laura E., Berg, Christine D., Berndt, Sonja I., Bertazzi, Pier Alberto, Biritwum, Richard B., Black, Amanda, Blot, William, Boeing, Heiner, Boffetta, Paolo, Bolton, Kelly, Boutron-Ruault, Marie-Christine, Bracci, Paige M., Brennan, Paul, Brinton, Louise A., Brotzman, Michelle, Bueno-de-Mesquita, H. Bas, Buring, Julie E., Butler, Mary Ann, Cai, Qiuyin, Cancel-Tassin, Geraldine, Canzian, Federico, Cao, Guangwen, Caporaso, Neil E., Carrato, Alfredo, Carreon, Tania, Carta, Angela, Chang, Gee-Chen, Chang, I-Shou, Chang-Claude, Jenny, Che, Xu, Chen, Chien-Jen, Chen, Chih-Yi, Chen, Chung-Hsing, Chen, Constance, Chen, Kuan-Yu, Chen, Yuh-Min, Chokkalingam, Anand P., Chu, Lisa W., Clavel-Chapelon, Francoise, Colditz, Graham A., Colt, Joanne S., Conti, David, Cook, Michael B., Cortessis, Victoria K., Crawford, E. David, Cussenot, Olivier, Davis, Faith G., De Vivo, Immaculata, Deng, Xiang, Ding, Ti, Dinney, Colin P., Di Stefano, Anna Luisa, Diver, W. Ryan, Duell, Eric J., Elena, Joanne W., Fan, Jin-Hu, Feigelson, Heather Spencer, Feychting, Maria, Figueroa, Jonine D., Flanagan, Adrienne M., Fraumeni, Joseph F., Jr, Freedman, Neal D., Fridley, Brooke L., Fuchs, Charles S., Gago-Dominguez, Manuela, Gallinger, Steven, Gao, Yu-Tang, Gapstur, Susan M., Garcia-Closas, Montserrat, Garcia-Closas, Reina, Gastier-Foster, Julie M., Gaziano, J. Michael, Gerhard, Daniela S., Giffen, Carol A., Giles, Graham G., Gillanders, Elizabeth M., Giovannucci, Edward L., Goggins, Michael, Gokgoz, Nalan, Goldstein, Alisa M., Gonzalez, Carlos, Gorlick, Richard, Greene, Mark H., Gross, Myron, Grossman, H. Barton, Grubb, Robert, III, Gu, Jian, Guan, Peng, Haiman, Christopher A., Hallmans, Goran, Hankinson, Susan E., Harris, Curtis C., Hartge, Patricia, Hattinger, Claudia, Hayes, Richard B., He, Qincheng, Helman, Lee, Henderson, Brian E., Henriksson, Roger, Hoffman-Bolton, Judith, Hohensee, Chancellor, Holly, Elizabeth A., Hong, Yun-Chul, Hoover, Robert N., Hosgood, H. Dean, III, Hsiao, Chin-Fu, Hsing, Ann W., Hsiung, Chao Agnes, Hu, Nan, Hu, Wei, Hu, Zhibin, Huang, Ming-Shyan, Hunter, David J., Inskip, Peter D., Ito, Hidemi, Jacobs, Eric J., Jacobs, Kevin B., Jenab, Mazda, Ji, Bu-Tian, Johansen, Christoffer, Johansson, Mattias, Johnson, Alison, Kaaks, Rudolf, Kamat, Ashish M., Kamineni, Aruna, Karagas, Margaret, Khanna, Chand, Khaw, Kay-Tee, Kim, Christopher, Kim, In-Sam, Kim, Jin Hee, Kim, Yeul Hong, Kim, Young-Chul, Kim, Young Tae, Kang, Chang Hyun, Jung, Yoo Jin, Kitahara, Cari M., Klein, Alison P., Klein, Robert, Kogevinas, Manolis, Koh, Woon-Puay, Kohno, Takashi, Kolonel, Laurence N., Kooperberg, Charles, Kratz, Christian P., Krogh, Vittorio, Kunitoh, Hideo, Kurtz, Robert C., Kurucu, Nilgun, Lan, Qing, Lathrop, Mark, Lau, Ching C., Lecanda, Fernando, Lee, Kyoung-Mu, Lee, Maxwell P., Le Marchand, Loic, Lerner, Seth P., Li, Donghui, Liao, Linda M., Lim, Wei-Yen, Lin, Dongxin, Lin, Jie, Lindstrom, Sara, Linet, Martha S., Lissowska, Jolanta, Liu, Jianjun, Ljungberg, Börje, Lloreta, Josep, Lu, Daru, Ma, Jing, Malats, Nuria, Mannisto, Satu, Marina, Neyssa, Mastrangelo, Giuseppe, Matsuo, Keitaro, McGlynn, Katherine A., McKean-Cowdin, Roberta, McNeill, Lorna H., McWilliams, Robert R., Melin, Beatrice S., Meltzer, Paul S., Mensah, James E., Miao, Xiaoping, Michaud, Dominique S., Mondul, Alison M., Moore, Lee E., Muir, Kenneth, Niwa, Shelley, Olson, Sara H., Orr, Nick, Panico, Salvatore, Park, Jae Yong, Patel, Alpa V., Patino-Garcia, Ana, Pavanello, Sofia, Peeters, Petra H. M., Peplonska, Beata, Peters, Ulrike, Petersen, Gloria M., Picci, Piero, Pike, Malcolm C., Porru, Stefano, Prescott, Jennifer, Pu, Xia, Purdue, Mark P., Qiao, You-Lin, Rajaraman, Preetha, Riboli, Elio, Risch, Harvey A., Rodabough, Rebecca J., Rothman, Nathaniel, Ruder, Avima M., Ryu, Jeong-Seon, Sanson, Marc, Schned, Alan, Schumacher, Fredrick R., Schwartz, Ann G., Schwartz, Kendra L., Schwenn, Molly, Scotlandi, Katia, Seow, Adeline, Serra, Consol, Serra, Massimo, Sesso, Howard D., Severi, Gianluca, Shen, Hongbing, Shen, Min, Shete, Sanjay, Shiraishi, Kouya, Shu, Xiao-Ou, Siddiq, Afshan, Sierrasesumaga, Luis, Sierri, Sabina, Loon Sihoe, Alan Dart, Silverman, Debra T., Simon, Matthias, Southey, Melissa C., Spector, Logan, Spitz, Margaret, Stampfer, Meir, Stattin, Par, Stern, Mariana C., Stevens, Victoria L., Stolzenberg-Solomon, Rachael Z., Stram, Daniel O., Strom, Sara S., Su, Wu-Chou, Sund, Malin, Sung, Sook Whan, Swerdlow, Anthony, Tan, Wen, Tanaka, Hideo, Tang, Wei, Tang, Ze-Zhang, Tardon, Adonina, Tay, Evelyn, Taylor, Philip R., Tettey, Yao, Thomas, David M., Tirabosco, Roberto, Tjonneland, Anne, Tobias, Geoffrey S., Toro, Jorge R., Travis, Ruth C., Trichopoulos, Dimitrios, Troisi, Rebecca, Truelove, Ann, Tsai, Ying-Huang, Tucker, Margaret A., Tumino, Rosario, Van Den Berg, David, Van Den Eeden, Stephen K., Vermeulen, Roel, Vineis, Paolo, Visvanathan, Kala, Vogel, Ulla, Wang, Chaoyu, Wang, Chengfeng, Wang, Junwen, Wang, Sophia S., Weiderpass, Elisabete, Weinstein, Stephanie J., Wentzensen, Nicolas, Wheeler, William, White, Emily, Wiencke, John K., Wolk, Alicja, Wolpin, Brian M., Wong, Maria Pik, Wrensch, Margaret, Wu, Chen, Wu, Tangchun, Wu, Xifeng, Wu, Yi-Long, Wunder, Jay S., Xiang, Yong-Bing, Xu, Jun, Yang, Hannah P., Yang, Pan-Chyr, Yatabe, Yasushi, Ye, Yuanqing, Yeboah, Edward D., Yin, Zhihua, Ying, Chen, Yu, Chong-Jen, Yu, Kai, Yuan, Jian-Min, Zanetti, Krista A., Zeleniuch-Jacquotte, Anne, Zheng, Wei, Zhou, Baosen, Mirabello, Lisa, Savage, Sharon A., Kraft, Peter, Chanock, Stephen J., Yeager, Meredith, Landi, Maria Terese, Shi, Jianxin, Chatterjee, Nilanjan, and Amundadottir, Laufey T.

Published
2014
Full Text
View/download PDF

15. Analysis of non-synonymous-coding variants of Parkinsonʼs disease-related pathogenic and susceptibility genes in East Asian populations

Author

Foo, Jia Nee, Tan, Louis C., Liany, Herty, Koh, Tat Hung, Irwan, Ishak D., Ng, Yen Yek, Ahmad-Annuar, Azlina, Au, Wing-Lok, Aung, Tin, Chan, Anne Y.Y., Chong, Siow-Ann, Chung, Sun Ju, Jung, Yusun, Khor, Chiea Chuen, Kim, Juyeon, Lee, Jimmy, Lim, Shen-Yang, Mok, Vincent, Prakash, Kumar-M., Song, Kyuyoung, Tai, E.-Shyong, Vithana, Eranga N., Wong, Tien-Yin, Tan, Eng-King, and Liu, Jianjun

Published
2014
Full Text
View/download PDF

16. A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2

Author

Wu, Ying, Gao, He, Li, Huaixing, Tabara, Yasuharu, Nakatochi, Masahiro, Chiu, Yen-Feng, Park, Eun Jung, Wen, Wanqing, Adair, Linda S., Borja, Judith B., Cai, Qiuyin, Chang, Yi-Cheng, Chen, Peng, Croteau-Chonka, Damien C., Fogarty, Marie P., Gan, Wei, He, Chih-Tsueng, Hsiung, Chao A., Hwu, Chii-Min, Ichihara, Sahoko, Igase, Michiya, Jo, Jaeseong, Kato, Norihiro, Kawamoto, Ryuichi, Kuzawa, Christophor W., Lee, Jeannette J.M., Liu, Jianjun, Lu, Ling, Mcdade, Thomas W., Osawa, Haruhiko, Sheu, Wayne H-H., Teo, Yvonne, Vadlamudi, Swarooparani, Van Dam, Rob M., Wang, Yiqin, Xiang, Yong-Bing, Yamamoto, Ken, Ye, Xingwang, Young, Terri L., Zheng, Wei, Zhu, Jingwen, Shu, Xiao-Ou, Shin, Chol, Jee, Sun Ha, Chuang, Lee-Ming, Miki, Tetsuro, Yokota, Mitsuhiro, Lin, Xu, Mohlke, Karen L, and Tai, E Shyong

Published
2014
Full Text
View/download PDF

19. Genome-wide copy number variation study in anorectal malformations

Author

Wong, Emily H.M., Cui, Long, Ng, Chun-Laam, Tang, Clara S.M., Liu, Xue-Lai, So, Man-Ting, Yip, Benjamin Hon-Kei, Cheng, Guo, Zhang, Ruizhong, Tang, Wai-Kiu, Yang, Wanling, Lau, Yu-Lung, Baum, Larry, Kwan, Patrick, Sun, Liang-Dan, Zuo, Xian-Bo, Ren, Yun-Qing, Yin, Xian-Yong, Miao, Xiao-Ping, Liu, Jianjun, Lui, Vincent Chi-Hang, Ngan, Elly Sau-Wai, Yuan, Zhen-Wei, Zhang, Shi-Wei, Xia, Jinglong, Wang, Hualong, Sun, Xiao-bing, Wang, Ruoyi, Chang, Tao, Chan, Ivy Hau-Yee, Chung, Patrick Ho-Yu, Zhang, Xue-Jun, Wong, Kenneth Kak-Yuen, Cherny, Stacey S., Sham, Pak-Chung, Tam, Paul Kwong-Hang, and Garcia-Barcelo, Maria-Mercè

Published
2013
Full Text
View/download PDF

20. The role of genetic breast cancer susceptibility variants as prognostic factors

Author

Fasching, Peter A., Pharoah, Paul D.P., Cox, Angela, Nevanlinna, Heli, Bojesen, Stig E., Karn, Thomas, Broeks, Annegien, van Leeuwen, Flora E., van ʼt Veer, Laura J., Udo, Renate, Dunning, Alison M., Greco, Dario, Aittomäki, Kristiina, Blomqvist, Carl, Shah, Mitul, Nordestgaard, Børge G., Flyger, Henrik, Hopper, John L., Southey, Melissa C., Apicella, Carmel, Garcia-Closas, Montserrat, Sherman, Mark, Lissowska, Jolanta, Seynaeve, Caroline, Huijts, Petra E.A., Tollenaar, Rob A.E.M., Ziogas, Argyrios, Ekici, Arif B., Rauh, Claudia, Mannermaa, Arto, Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M., Andrulis, Irene L., Ozcelik, Hilmi, Mulligan, Anna-Marie, Glendon, Gord, Hall, Per, Czene, Kamila, Liu, Jianjun, Chang-Claude, Jenny, Wang-Gohrke, Shan, Eilber, Ursula, Nickels, Stefan, Dörk, Thilo, Schiekel, Maria, Bremer, Michael, Park-Simon, Tjoung-Won, Giles, Graham G., Severi, Gianluca, Baglietto, Laura, Hooning, Maartje J., Martens, John W.M., Jager, Agnes, Kriege, Mieke, Lindblom, Annika, Margolin, Sara, Couch, Fergus J., Stevens, Kristen N., Olson, Janet E., Kosel, Matthew, Cross, Simon S., Balasubramanian, Sabapathy P., Reed, Malcolm W.R., Miron, Alexander, John, Esther M., Winqvist, Robert, Pylkäs, Katri, Jukkola-Vuorinen, Arja, Kauppila, Saila, Burwinkel, Barbara, Marme, Frederik, Schneeweiss, Andreas, Sohn, Christof, Chenevix-Trench, Georgia, Lambrechts, Diether, Dieudonne, Anne-Sophie, Hatse, Sigrid, van Limbergen, Erik, Benitez, Javier, Milne, Roger L., Zamora, M. Pilar, Pérez, José Ignacio Arias, Bonanni, Bernardo, Peissel, Bernard, Loris, Bernard, Peterlongo, Paolo, Rajaraman, Preetha, Schonfeld, Sara J., Anton-Culver, Hoda, Devilee, Peter, Beckmann, Matthias W., Slamon, Dennis J., Phillips, Kelly-Anne, Figueroa, Jonine D., Humphreys, Manjeet K., Easton, Douglas F., and Schmidt, Marjanka K.

Published
2012
Full Text
View/download PDF

21. Identification of a novel percent mammographic density locus at 12q24

Author

Stevens, Kristen N., Lindstrom, Sara, Scott, Christopher G., Thompson, Deborah, Sellers, Thomas A., Wang, Xianshu, Wang, Alice, Atkinson, Elizabeth, Rider, David N., Eckel-Passow, Jeanette E., Varghese, Jajini S., Audley, Tina, Brown, Judith, Leyland, Jean, Luben, Robert N., Warren, Ruth M.L., Loos, Ruth J.F., Wareham, Nicholas J., Li, Jingmei, Hall, Per, Liu, Jianjun, Eriksson, Louise, Czene, Kamila, Olson, Janet E., Shane Pankratz, V., Fredericksen, Zachary, Diasio, Robert B., Lee, Adam M., Heit, John A., deAndrade, Mariza, Goode, Ellen L., Vierkant, Robert A., Cunningham, Julie M., Armasu, Sebastian M., Weinshilboum, Richard, Fridley, Brooke L., Batzler, Anthony, Ingle, James N., Boyd, Norman F., Paterson, Andrew D., Rommens, Johanna, Martin, Lisa J., Hopper, John L., Southey, Melissa C., Stone, Jennifer, Apicella, Carmel, Kraft, Peter, Hankinson, Susan E., Hazra, Aditi, Hunter, David J., Easton, Douglas F., Couch, Fergus J., Tamimi, Rulla M., and Vachon, Celine M.

Published
2012
Full Text
View/download PDF

22. Identification of four novel variants that influence central corneal thickness in multi-ethnic Asian populations

Author

Cornes, Belinda K., Khor, Chiea Chuen, Nongpiur, Monisha E., Xu, Liang, Tay, Wan-Ting, Zheng, Yingfeng, Lavanya, Raghavan, Li, Yang, Wu, Renyi, Sim, Xueling, Wang, Ya-Xing, Chen, Peng, Teo, Yik Ying, Chia, Kee-Seng, Seielstad, Mark, Liu, Jianjun, Hibberd, Martin L., Cheng, Ching-Yu, Saw, Seang-Mei, Tai, E-Shyong, Jonas, Jost B., Vithana, Eranga N., Wong, Tien Y., and Aung, Tin

Published
2012
Full Text
View/download PDF

24. Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

Author

Broeks, Annegien, Schmidt, Marjanka K., Sherman, Mark E., Couch, Fergus J., Hopper, John L., Dite, Gillian S., Apicella, Carmel, Smith, Letitia D., Hammet, Fleur, Southey, Melissa C., Van ’t Veer, Laura J., de Groot, Renate, Smit, Vincent T.H.B.M., Fasching, Peter A., Beckmann, Matthias W., Jud, Sebastian, Ekici, Arif B., Hartmann, Arndt, Hein, Alexander, Schulz-Wendtland, Ruediger, Burwinkel, Barbara, Marme, Frederik, Schneeweiss, Andreas, Sinn, Hans-Peter, Sohn, Christof, Tchatchou, Sandrine, Bojesen, Stig E., Nordestgaard, Børge G., Flyger, Henrik, Ørsted, David D., Kaur-Knudsen, Diljit, Milne, Roger L., Pérez, Jose I. Arias, Zamora, Pilar, Rodríguez, Primitiva Menéndez, Benítez, Javier, Brauch, Hiltrud, Justenhoven, Christina, Ko, Yon-Dschun, Hamann, Ute, Fischer, Hans-Peter, Brüning, Thomas, Pesch, Beate, Chang-Claude, Jenny, Wang-Gohrke, Shan, Bremer, Michael, Karstens, Johann H., Hillemanns, Peter, Dörk, Thilo, Nevanlinna, Heli A., Heikkinen, Tuomas, Heikkilä, Päivi, Blomqvist, Carl, Aittomäki, Kristiina, Aaltonen, Kirsimari, Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Kosma, Veli-Matti, Kauppinen, Jaana M., Kataja, Vesa, Auvinen, Päivi, Eskelinen, Matti, Soini, Ylermi, Chenevix-Trench, Georgia, Spurdle, Amanda B., Beesley, Jonathan, Chen, Xiaoqing, Holland, Helene, Lambrechts, Diether, Claes, Bart, Vandorpe, Thijs, Neven, Patrick, Wildiers, Hans, Flesch-Janys, Dieter, Hein, Rebecca, Löning, Thomas, Kosel, Matthew, Fredericksen, Zachary S., Wang, Xianshu, Giles, Graham G., Baglietto, Laura, Severi, Gianluca, McLean, Catriona, Haiman, Christopher A., Henderson, Brian E., Le Marchand, Loic, Kolonel, Laurence N., Grenaker Alnæs, Grethe, Kristensen, Vessela, Børresen-Dale, Anne-Lise, Hunter, David J., Hankinson, Susan E., Andrulis, Irene L., Marie Mulligan, Anna, OʼMalley, Frances P., Devilee, Peter, Huijts, Petra E.A., Tollenaar, Rob A.E.M., Van Asperen, Christi J., Seynaeve, Caroline S., Chanock, Stephen J., Lissowska, Jolanta, Brinton, Louise, Peplonska, Beata, Figueroa, Jonine, Yang, Xiaohong R., Hooning, Maartje J., Hollestelle, Antoinette, Oldenburg, Rogier A., Jager, Agnes, Kriege, Mieke, Ozturk, Bahar, van Leenders, Geert J.L.H., Hall, Per, Czene, Kamila, Humphreys, Keith, Liu, Jianjun, Cox, Angela, Connley, Daniel, Cramp, Helen E., Cross, Simon S., Balasubramanian, Sabapathy P., Reed, Malcolm W.R., Dunning, Alison M., Easton, Douglas F., Humphreys, Manjeet K., Caldas, Carlos, Blows, Fiona, Driver, Kristy, Provenzano, Elena, Lubinski, Jan, Jakubowska, Anna, Huzarski, Tomasz, Byrski, Tomasz, Cybulski, Cezary, Gorski, Bohdan, Gronwald, Jacek, Brennan, Paul, Sangrajrang, Suleeporn, Gaborieau, Valerie, Shen, Chen-Yang, Hsiung, Chia-Ni, Yu, Jyh-Cherng, Chen, Shou-Tung, Hsu, Giu-Cheng, Hou, Ming-Feng, Huang, Chiun-Sheng, Anton-Culver, Hoda, Ziogas, Argyrios, Pharoah, Paul D.P., and Garcia-Closas, Montserrat

Published
2011
Full Text
View/download PDF

27. Association between GWAS-identified lung adenocarcinoma susceptibility loci andEGFRmutations in never-smoking Asian women, and comparison with findings from Western populations

Author

Seow, Wei Jie, primary, Matsuo, Keitaro, additional, Hsiung, Chao Agnes, additional, Shiraishi, Kouya, additional, Song, Minsun, additional, Kim, Hee Nam, additional, Wong, Maria Pik, additional, Hong, Yun-Chul, additional, Hosgood, H. Dean, additional, Wang, Zhaoming, additional, Chang, I-Shou, additional, Wang, Jiu-Cun, additional, Chatterjee, Nilanjan, additional, Tucker, Margaret, additional, Wei, Hu, additional, Mitsudomi, Tetsuya, additional, Zheng, Wei, additional, Kim, Jin Hee, additional, Zhou, Baosen, additional, Caporaso, Neil E., additional, Albanes, Demetrius, additional, Shin, Min-Ho, additional, Chung, Lap Ping, additional, An, She-Juan, additional, Wang, Ping, additional, Zheng, Hong, additional, Yatabe, Yasushi, additional, Zhang, Xu-Chao, additional, Kim, Young Tae, additional, Shu, Xiao-Ou, additional, Kim, Young-Chul, additional, Bassig, Bryan A., additional, Chang, Jiang, additional, Ho, James Chung Man, additional, Ji, Bu-Tian, additional, Kubo, Michiaki, additional, Daigo, Yataro, additional, Ito, Hidemi, additional, Momozawa, Yukihide, additional, Ashikawa, Kyota, additional, Kamatani, Yoichiro, additional, Honda, Takayuki, additional, Sakamoto, Hiromi, additional, Kunitoh, Hideo, additional, Tsuta, Koji, additional, Watanabe, Shun-Ichi, additional, Nokihara, Hiroshi, additional, Miyagi, Yohei, additional, Nakayama, Haruhiko, additional, Matsumoto, Shingo, additional, Tsuboi, Masahiro, additional, Goto, Koichi, additional, Yin, Zhihua, additional, Shi, Jianxin, additional, Takahashi, Atsushi, additional, Goto, Akiteru, additional, Minamiya, Yoshihiro, additional, Shimizu, Kimihiro, additional, Tanaka, Kazumi, additional, Wu, Tangchun, additional, Wei, Fusheng, additional, Wong, Jason Y.Y., additional, Matsuda, Fumihiko, additional, Su, Jian, additional, Kim, Yeul Hong, additional, Oh, In-Jae, additional, Song, Fengju, additional, Lee, Victor Ho Fun, additional, Su, Wu-Chou, additional, Chen, Yuh-Min, additional, Chang, Gee-Chen, additional, Chen, Kuan-Yu, additional, Huang, Ming-Shyan, additional, Yang, Pan-Chyr, additional, Lin, Hsien-Chih, additional, Xiang, Yong-Bing, additional, Seow, Adeline, additional, Park, Jae Yong, additional, Kweon, Sun-Seog, additional, Chen, Chien-Jen, additional, Li, Haixin, additional, Gao, Yu-Tang, additional, Wu, Chen, additional, Qian, Biyun, additional, Lu, Daru, additional, Liu, Jianjun, additional, Jeon, Hyo-Sung, additional, Hsiao, Chin-Fu, additional, Sung, Jae Sook, additional, Tsai, Ying-Huang, additional, Jung, Yoo Jin, additional, Guo, Huan, additional, Hu, Zhibin, additional, Wang, Wen-Chang, additional, Chung, Charles C., additional, Lawrence, Charles, additional, Burdett, Laurie, additional, Yeager, Meredith, additional, Jacobs, Kevin B., additional, Hutchinson, Amy, additional, Berndt, Sonja I., additional, He, Xingzhou, additional, Wu, Wei, additional, Wang, Junwen, additional, Li, Yuqing, additional, Choi, Jin Eun, additional, Park, Kyong Hwa, additional, Sung, Sook Whan, additional, Liu, Li, additional, Kang, Chang Hyun, additional, Hu, Lingmin, additional, Chen, Chung-Hsing, additional, Yang, Tsung-Ying, additional, Xu, Jun, additional, Guan, Peng, additional, Tan, Wen, additional, Wang, Chih-Liang, additional, Sihoe, Alan Dart Loon, additional, Chen, Ying, additional, Choi, Yi Young, additional, Hung, Jen-Yu, additional, Kim, Jun Suk, additional, Yoon, Ho-Il, additional, Cai, Qiuyin, additional, Lin, Chien-Chung, additional, Park, In Kyu, additional, Xu, Ping, additional, Dong, Jing, additional, Kim, Christopher, additional, He, Qincheng, additional, Perng, Reury-Perng, additional, Chen, Chih-Yi, additional, Vermeulen, Roel, additional, Wu, Junjie, additional, Lim, Wei-Yen, additional, Chen, Kun-Chieh, additional, Chan, John K.C., additional, Chu, Minjie, additional, Li, Yao-Jen, additional, Li, Jihua, additional, Chen, Hongyan, additional, Yu, Chong-Jen, additional, Jin, Li, additional, Lo, Yen-Li, additional, Chen, Ying-Hsiang, additional, Fraumeni, Joseph F., additional, Liu, Jie, additional, Yamaji, Taiki, additional, Yang, Yang, additional, Hicks, Belynda, additional, Wyatt, Kathleen, additional, Li, Shengchao A., additional, Dai, Juncheng, additional, Ma, Hongxia, additional, Jin, Guangfu, additional, Song, Bao, additional, Wang, Zhehai, additional, Cheng, Sensen, additional, Li, Xuelian, additional, Ren, Yangwu, additional, Cui, Ping, additional, Iwasaki, Motoki, additional, Shimazu, Taichi, additional, Tsugane, Shoichiro, additional, Zhu, Junjie, additional, Jiang, Gening, additional, Fei, Ke, additional, Wu, Guoping, additional, Chien, Li-Hsin, additional, Chen, Hui-Ling, additional, Su, Yu-Chun, additional, Tsai, Fang-Yu, additional, Chen, Yi-Song, additional, Yu, Jinming, additional, Stevens, Victoria L., additional, Laird-Offringa, Ite A., additional, Marconett, Crystal N., additional, Lin, Dongxin, additional, Chen, Kexin, additional, Wu, Yi-Long, additional, Landi, Maria Teresa, additional, Shen, Hongbing, additional, Rothman, Nathaniel, additional, Kohno, Takashi, additional, Chanock, Stephen J., additional, and Lan, Qing, additional

Published
2016
Full Text
View/download PDF

28. Genome-wide association study of Parkinson’s disease in East Asians

Author

Foo, Jia Nee, primary, Tan, Louis C., additional, Irwan, Ishak D., additional, Au, Wing-Lok, additional, Low, Hui Qi, additional, Prakash, Kumar-M., additional, Ahmad-Annuar, Azlina, additional, Bei, Jinxin, additional, Chan, Anne YY, additional, Chen, Chiung Mei, additional, Chen, Yi-Chun, additional, Chung, Sun Ju, additional, Deng, Hao, additional, Lim, Shen-Yang, additional, Mok, Vincent, additional, Pang, Hao, additional, Pei, Zhong, additional, Peng, Rong, additional, Shang, Hui-Fang, additional, Song, Kyuyoung, additional, Tan, Ai Huey, additional, Wu, Yih-Ru, additional, Aung, Tin, additional, Cheng, Ching-Yu, additional, Chew, Fook Tim, additional, Chew, Soo-Hong, additional, Chong, Siow-Ann, additional, Ebstein, Richard P, additional, Lee, Jimmy, additional, Saw, Seang-Mei, additional, Seow, Adeline, additional, Subramaniam, Mythily, additional, Tai, E-Shyong, additional, Vithana, Eranga N, additional, Wong, Tien-Yin, additional, Heng, Khai Koon, additional, Meah, Wee-Yang, additional, Khor, Chiea Chuen, additional, Liu, Hong, additional, Zhang, Furen, additional, Liu, Jianjun, additional, and Tan, Eng-King, additional

Published
2016
Full Text
View/download PDF

29. An extended genome-wide association study identifies novel susceptibility loci for nasopharyngeal carcinoma

Author

Cui, Qian, primary, Feng, Qi-Sheng, additional, Mo, Hao-Yuan, additional, Sun, Jian, additional, Xia, Yun-Fei, additional, Zhang, Hongxing, additional, Foo, Jia Nee, additional, Guo, Yun-Miao, additional, Chen, Li-Zhen, additional, Li, Ming, additional, Liu, Wen-Sheng, additional, Xu, Miao, additional, Zhou, Gangqiao, additional, He, Fuchu, additional, Yu, Xueqing, additional, Jia, Wei-Hua, additional, Liu, Jianjun, additional, Zeng, Yi-Xin, additional, and Bei, Jin-Xin, additional

Published
2016
Full Text
View/download PDF

30. Fine mapping the MHC region identified four independent variants modifying susceptibility to chronic hepatitis B in Han Chinese

Author

Zhu, Meng, primary, Dai, Juncheng, additional, Wang, Cheng, additional, Wang, Yuzhuo, additional, Qin, Na, additional, Ma, Hongxia, additional, Song, Ci, additional, Zhai, Xiangjun, additional, Yang, Yuan, additional, Liu, Jibin, additional, Liu, Li, additional, Li, Shengping, additional, Liu, Jianjun, additional, Yang, Haitao, additional, Zhu, Fengcai, additional, Shi, Yongyong, additional, Shen, Hongbing, additional, Jin, Guangfu, additional, Zhou, Weiping, additional, and Hu, Zhibin, additional

Published
2016
Full Text
View/download PDF

31. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci

Author

He, Meian, primary, Xu, Min, additional, Zhang, Ben, additional, Liang, Jun, additional, Chen, Peng, additional, Lee, Jong-Young, additional, Johnson, Todd A., additional, Li, Huaixing, additional, Yang, Xiaobo, additional, Dai, Juncheng, additional, Liang, Liming, additional, Gui, Lixuan, additional, Qi, Qibin, additional, Huang, Jinyan, additional, Li, Yanping, additional, Adair, Linda S., additional, Aung, Tin, additional, Cai, Qiuyin, additional, Cheng, Ching-Yu, additional, Cho, Myeong-Chan, additional, Cho, Yoon Shin, additional, Chu, Minjie, additional, Cui, Bin, additional, Gao, Yu-Tang, additional, Go, Min Jin, additional, Gu, Dongfeng, additional, Gu, Weiqiong, additional, Guo, Huan, additional, Hao, Yongchen, additional, Hong, Jie, additional, Hu, Zhibin, additional, Hu, Yanling, additional, Huang, Jianfeng, additional, Hwang, Joo-Yeon, additional, Ikram, Mohammad Kamran, additional, Jin, Guangfu, additional, Kang, Dae-Hee, additional, Khor, Chiea Chuen, additional, Kim, Bong-Jo, additional, Kim, Hung Tae, additional, Kubo, Michiaki, additional, Lee, Jeannette, additional, Lee, Juyoung, additional, Lee, Nanette R., additional, Li, Ruoying, additional, Li, Jun, additional, Liu, JianJun, additional, Longe, Jirong, additional, Lu, Wei, additional, Lu, Xiangfeng, additional, Miao, Xiaoping, additional, Okada, Yukinori, additional, Ong, Rick Twee-Hee, additional, Qiu, Gaokun, additional, Seielstad, Mark, additional, Sim, Xueling, additional, Song, Huaidong, additional, Takeuchi, Fumihiko, additional, Tanaka, Toshihiro, additional, Taylor, Phil R., additional, Wang, Laiyuan, additional, Wang, Weiqing, additional, Wang, Yiqin, additional, Wu, Chen, additional, Wu, Ying, additional, Xiang, Yong-Bing, additional, Yamamoto, Ken, additional, Yang, Handong, additional, Liao, Ming, additional, Yokota, Mitsuhiro, additional, Young, Terri, additional, Zhang, Xiaomin, additional, Kato, Norihiro, additional, Wang, Qing K., additional, Zheng, Wei, additional, Hu, Frank B., additional, Lin, Dongxin, additional, Shen, Hongbing, additional, Teo, Yik Ying, additional, Mo, Zengnan, additional, Wong, Tien Yin, additional, Lin, Xu, additional, Mohlke, Karen L., additional, Ning, Guang, additional, Tsunoda, Tatsuhiko, additional, Han, Bok-Ghee, additional, Shu, Xiao-Ou, additional, Tai, E. Shyong, additional, Wu, Tangchun, additional, and Qi, Lu, additional

Published
2014
Full Text
View/download PDF

32. A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2

Author

Wu, Ying, primary, Gao, He, additional, Li, Huaixing, additional, Tabara, Yasuharu, additional, Nakatochi, Masahiro, additional, Chiu, Yen-Feng, additional, Park, Eun Jung, additional, Wen, Wanqing, additional, Adair, Linda S., additional, Borja, Judith B., additional, Cai, Qiuyin, additional, Chang, Yi-Cheng, additional, Chen, Peng, additional, Croteau-Chonka, Damien C., additional, Fogarty, Marie P., additional, Gan, Wei, additional, He, Chih-Tsueng, additional, Hsiung, Chao A., additional, Hwu, Chii-Min, additional, Ichihara, Sahoko, additional, Igase, Michiya, additional, Jo, Jaeseong, additional, Kato, Norihiro, additional, Kawamoto, Ryuichi, additional, Kuzawa, Christophor W., additional, Lee, Jeannette J.M., additional, Liu, Jianjun, additional, Lu, Ling, additional, Mcdade, Thomas W., additional, Osawa, Haruhiko, additional, Sheu, Wayne H-H., additional, Teo, Yvonne, additional, Vadlamudi, Swarooparani, additional, Van Dam, Rob M., additional, Wang, Yiqin, additional, Xiang, Yong-Bing, additional, Yamamoto, Ken, additional, Ye, Xingwang, additional, Young, Terri L., additional, Zheng, Wei, additional, Zhu, Jingwen, additional, Shu, Xiao-Ou, additional, Shin, Chol, additional, Jee, Sun Ha, additional, Chuang, Lee-Ming, additional, Miki, Tetsuro, additional, Yokota, Mitsuhiro, additional, Lin, Xu, additional, Mohlke, Karen L, additional, and Tai, E Shyong, additional

Published
2013
Full Text
View/download PDF

33. Genome-wide copy number variation study in anorectal malformations

Author

Wong, Emily H.M., primary, Cui, Long, additional, Ng, Chun-Laam, additional, Tang, Clara S.M., additional, Liu, Xue-Lai, additional, So, Man-Ting, additional, Yip, Benjamin Hon-Kei, additional, Cheng, Guo, additional, Zhang, Ruizhong, additional, Tang, Wai-Kiu, additional, Yang, Wanling, additional, Lau, Yu-Lung, additional, Baum, Larry, additional, Kwan, Patrick, additional, Sun, Liang-Dan, additional, Zuo, Xian-Bo, additional, Ren, Yun-Qing, additional, Yin, Xian-Yong, additional, Miao, Xiao-Ping, additional, Liu, Jianjun, additional, Lui, Vincent Chi-Hang, additional, Ngan, Elly Sau-Wai, additional, Yuan, Zhen-Wei, additional, Zhang, Shi-Wei, additional, Xia, Jinglong, additional, Wang, Hualong, additional, Sun, Xiao-bing, additional, Wang, Ruoyi, additional, Chang, Tao, additional, Chan, Ivy Hau-Yee, additional, Chung, Patrick Ho-Yu, additional, Zhang, Xue-Jun, additional, Wong, Kenneth Kak-Yuen, additional, Cherny, Stacey S., additional, Sham, Pak-Chung, additional, Tam, Paul Kwong-Hang, additional, and Garcia-Barcelo, Maria-Mercè, additional

Published
2012
Full Text
View/download PDF

34. Identification of four novel variants that influence central corneal thickness in multi-ethnic Asian populations

Author

Cornes, Belinda K., primary, Khor, Chiea Chuen, additional, Nongpiur, Monisha E., additional, Xu, Liang, additional, Tay, Wan-Ting, additional, Zheng, Yingfeng, additional, Lavanya, Raghavan, additional, Li, Yang, additional, Wu, Renyi, additional, Sim, Xueling, additional, Wang, Ya-Xing, additional, Chen, Peng, additional, Teo, Yik Ying, additional, Chia, Kee-Seng, additional, Seielstad, Mark, additional, Liu, Jianjun, additional, Hibberd, Martin L., additional, Cheng, Ching-Yu, additional, Saw, Seang-Mei, additional, Tai, E-Shyong, additional, Jonas, Jost B., additional, Vithana, Eranga N., additional, Wong, Tien Y., additional, and Aung, Tin, additional

Published
2011
Full Text
View/download PDF

36. multi-ancestry genome-wide study incorporating gene–smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.

Author

Sung, Yun Ju, de las Fuentes, Lisa, Winkler, Thomas W, Chasman, Daniel I, Bentley, Amy R, Kraja, Aldi T, Ntalla, Ioanna, Warren, Helen R, Guo, Xiuqing, Schwander, Karen, Manning, Alisa K, Brown, Michael R, Aschard, Hugues, Feitosa, Mary F, Franceschini, Nora, Lu, Yingchang, Cheng, Ching-Yu, Sim, Xueling, Vojinovic, Dina, and Marten, Jonathan

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results