1. Effectiveness of 10-year vaccination (2001-2010) on Hepatitis A in Tianjin, China.
- Author
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Zhang ZL, Zhu XJ, Shan AL, Gao ZG, Zhang Y, Ding YX, Liu H, Wu WS, Liu Y, He HY, Xie XH, Xia WD, Li C, Xu WT, Li ZY, Lin HL, and Fu WM
- Subjects
- Adolescent, Adult, Child, Child, Preschool, China epidemiology, Cross-Sectional Studies, Female, Health Services Research, Hepatitis A Antibodies blood, Humans, Immunization Programs, Immunoglobulin G blood, Incidence, Infant, Male, Middle Aged, Seroepidemiologic Studies, Treatment Outcome, Young Adult, Hepatitis A epidemiology, Hepatitis A prevention & control, Hepatitis A Vaccines administration & dosage, Hepatitis A Vaccines immunology, Vaccination statistics & numerical data
- Abstract
Vaccination is an effective strategy to prevent and control the transmission of hepatitis A. Hepatitis A immunization program has been taken into effect since 2001 in Tianjin, China. This study evaluated the effectiveness of strategies in the prevention and control of hepatitis A. Data of serological survey, annual hepatitis A incidence, immunization coverage and the positive rate of hepatitis A IgG before and after the immunization program in residents under 15 years old were used to do the analysis. The results indicated that hepatitis A vaccine induced a striking decrease of hepatitis A incidence and a significant increase in the positive rate of anti-HAV IgG among the children younger than 15 years old. Hepatitis A vaccination in children was proved to be effective in the prevention and control of hepatitis A in Tianjin, China.
- Published
- 2014
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