1. Novel estimation of the electrical bioimpedance using the local polynomial method. Application to in vivo real-time myocardium tissue impedance characterization during the cardiac cycle
- Author
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Benjamin Sanchez, Ramon Bragós, Gerd Vandersteen, Joannes Schoukens, Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica, Universitat Politècnica de Catalunya. IEB - Instrumentació Electrònica i Biomèdica, and Electricity
- Subjects
Frequency response ,Materials science ,Swine ,Biomedical Engineering ,Impedance spectroscopy ,electrical bioimpedance (EBI) ,local polynomial method (LPM) ,Espectroscòpia d'impedància ,Signal-To-Noise Ratio ,Multisine excitation ,Broadband electrical impedance spectroscopy (EIS) ,Instrumentació -- Mesurament ,In vivo ,Polynomial method ,Electronic engineering ,Animals ,Electrical impedance ,Tissue impedance ,Leakage (electronics) ,Signal processing ,Cardiac cycle ,Models, Cardiovascular ,Reproducibility of Results ,Heart ,Signal Processing, Computer-Assisted ,myocardium tissue electrical impedance ,multisine excitation ,Dielectric Spectroscopy ,Regression Analysis ,Enginyeria electrònica::Instrumentació i mesura [Àrees temàtiques de la UPC] ,Female ,Biomedical engineering - Abstract
Classicalmeasurements ofmyocardium tissue electrical impedance for characterizing the morphology of myocardium cells, as well as cell membranes integrity and intra/extra cellular spaces, are based on the frequency-sweep electrical impedance spectroscopy (EIS) technique. In contrast to the frequency-sweep EIS approach, measuring with broadband signals, i.e., multisine excitations, enables to collect, simultaneously, multiple myocardium tissue impedance data in a short measuring time. However, reducing the measuring time makes the measurements to be prone to the influence of the transients introduced by noise and the dynamic time-varying properties of tissue. This paper presents a novel approach for the impedance-frequency-response estimation based on the local polynomial method (LPM). The fast LPM version presented rejects the leakage error’s influence on the impedance frequency response when measuring electrical bioimpedance in a short time. The theory is supported by a set of validation measurements. Novel preliminary experimental results obtained from real-time in vivo healthy myocardium tissue impedance characterization within the cardiac cycle using multisine excitation are reported.
- Published
- 2011