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This paper presents a comparative evaluation of eight high-voltage step-up converters based on different associations of boost and zeta standard dc–dc pulse width modulation (PWM) cells. These eight converters present different characteristics such as cascaded and stacked PWM cell associations, as well as isolated winding coupled inductors, tapped winding coupled inductors, and noncoupled inductors. In order to explore the advantages and address the limitations of each topology, several comparative evaluations concerning static voltage gain, power losses, current and voltage stresses, component stress factors, power density, relative cost, and efficiency were carried out. From the theoretical analysis and experimental results, the association named stacked boost–zeta with autotransformer yielded the highest efficiency and power density and resulted in the most attractive converter for the case study. [ABSTRACT FROM PUBLISHER]