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With an incredible increase in the number of wireless devices and an ever-growing demand for high data rates, 5G needs to provide a solution to satisfy the demand for the next decade. Multiple-input multiple-output (MIMO) systems are seen as one of the primary solutions—allowing for spatial multiplexing and the use of millimeter-wave (mmWave) frequencies, which can provide much larger bandwidths and, thus, data rates. MIMO is very closely related to phased arrays, which have been used for radar for the past few decades and requires many antennas and transceivers—on the order of hundreds or thousands for massive MIMO. To make such systems affordable, low-cost, low-power, and low-complexity is required—inherently compromising other system characteristics, such as linearity. The main focus of this paper will be in summarizing the challenges, recent advances, and potential future breakthroughs concerning MIMO/digital array sensitivity to interferers and nonlinear distortion. Specifically, this paper gives an overview of MIMO/digital array architectures and different techniques currently researched for the characterization and mitigation of spatial and spectral interferers and nonlinearities, which can be used to extend the effective dynamic range of low-cost MIMO/digital array systems. [ABSTRACT FROM AUTHOR]