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We propose a learning-based, distributionally robust model predictive control approach towards the design of adaptive cruise control (ACC) systems. We model the preceding vehicle as an autonomous stochastic system, using a hybrid model with continuous dynamics and discrete, Markovian inputs. We estimate the (unknown) transition probabilities of this model empirically using observed mode transitions and simultaneously determine sets of probability vectors (ambiguity sets) around these estimates, that contain the true transition probabilities with high confidence. We then solve a risk-averse optimal control problem that assumes the worst-case distributions in these sets. We furthermore derive a robust terminal constraint set and use it to establish recursive feasibility of the resulting MPC scheme. We validate the theoretical results and demonstrate desirable properties of the scheme through closed-loop simulations., Accepted for publication in the IFAC World Congress 2020; extended version with proofs

This paper presents a novel model predictive control strategy for controlling autonomous motion systems moving through an environment with obstacles of general shape. In order to solve such a generic non-convex optimization problem and find a feasible trajectory that reaches the destination, the approach employs a quadratic penalty method to enforce the obstacle avoidance constraints, and several heuristics to bypass local minima behind an obstacle. The quadratic penalty method itself aids in avoiding such local minima by gradually finding a path around the obstacle as the penalty factors are successively increased. The inner optimization problems are solved in real time using the proximal averaged Newton-type method for optimal control (PANOC), a first-order method which exhibits low runtime and is suited for embedded applications. The method is validated by extensive numerical simulations and shown to outperform state-of-the-art solvers in runtime and robustness., 7 pages

Fractional-order dynamical systems were recently introduced in the field of pharmacokinetics where they proved powerful tools for modeling the absorption, disposition, distribution and excretion of drugs which are liable to anomalous diffusion, deep tissue trapping and other nonlinear phenomena. In this paper we present several ways to simulate such fractional-order pharmacokinetic models and we evaluate their accuracy and complexity on a fractional-order pharmacokinetic model of Amiodarone, an anti-arrhythmic drug. We then propose an optimal administration scheduling scheme and evaluate it on a population of patients.

The optimization of process economics within the model predictive control (MPC) formulation has given rise to a new control paradigm known as economic MPC (EMPC). Several authors have discussed the closed-loop properties of EMPC-controlled deterministic systems, however, little have uncertain systems been studied. In this paper we propose EMPC formulations for nonlinear Markovian switching systems which guarantee recursive feasibility, asymptotic performance bounds and constrained mean square (MS) stability.

Stochastic optimal control problems are typically of rather large scale involving millions of decision variables, but possess a certain structure which can be exploited by first-order methods such as forward-backward splitting and the alternating direction method of multipliers (ADMM). In this paper, we use the forward-backward envelope, a real-valued continuously differentiable penalty function, to recast the dual of the original nonsmooth problem as an unconstrained problem which we solve via the limited-memory BFGS algorithm. We show that the proposed method leads to a significant improvement of the convergence rate without increasing much the computational cost per iteration.