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Grass pollen allergens are shown to remain associated with protein material and a yellow pigment during paper chromatography and during dialyses and ultrafiltrations of various types. Dialysable* allergens comprise only a fraction of I per cent of the total activity and the amount of activity extractable by diethylene glycol (DEG) and similar solvents is of the same order. Besides the allergens, the DEG and aqueous extracts contain large amounts of inositol, glucose and fructose, also some yellow pigments and phosphates. Larger amounts of free and combined amino acids are found in the aqueous than in the DEG extracts, but the reverse is true for sucrose. In addition the DEG extracts contain a yellow glucoside different from the dactylen of the aqueous extracts, a glucosan and an arabinose-galactose-pigment complex, only the latter being associated with any activity. The spontaneous release of the crystalline dactylen from originally clear aqueous pollen extracts is found not to be caused by enzymes. The washed crystals are found to be chromatographically and electrophoretically homogeneous and devoid of allergenic activity. [ABSTRACT FROM AUTHOR]

Presents a list of papers on immunology to be published by 'Immunology' journal.

Presents a list of research papers to be published in the forthcoming issues of the journal 'Immunology.'

Presents research papers on immunology to be published by the periodical 'Immunology' in 2003. 'A CR1 polymorphism associated with constitutive erythrocyte CR1 levels affects binding yp C4b but not C3b,' by Daniel Birmingham et al; 'DS-Nh as an experimental model of atopic dermatitis induced by Staphylococcus aureus producing staphylococcal enterotoxin C,' by Tekshi Yoshioka et al.

Presents a list of forthcoming papers on immunology, as of January 2003. Signaling transduction pathway for eotaxin- and interleukin-5 induced eosinophil shape change; Recognition of bovine respiratory syncytial virus proteins by bovine lymphocytes; Prevention of oral tolerance induction by administration of exogenous interleukins.

Lists forthcoming papers slated for publication in the periodical 'Immunology,' compiled as of 2002.

Lists papers lined up for publication in the periodical 'Tumor Immunology' after the October 2002 issue. Titles and authors.

The antigenic components of adrenal extract were fractionated by chromatography on DEAE-cellulose. Using a stepwise elution procedure, it was found that a component of major interest, termed Pk3b, was eluted by a buffer of pH 6.70 and 0.09 M in phosphate-chloride. This antigenic preparation reacted with several rabbit antisera that had been prepared by isoimmunization with rabbit adrenal homogenate, in contrast to several other fractions, which reacted with only one (or two) of the antisera. Pk3b also showed a high degree of homogeneity, as shown by immunodiffusion, paper electrophoresis, and analytical ultracentrifugation. By the latter technique, an extrapolated sedimentation coefficient of 4.45S was determined. The further comparison of this antigen in immunodiffusion, along with an antiserum and the adrenal extract from the antiserum-providing animal, confirmed again that this is an autoantigen, and that it is one of five autoantigens of the adrenal gland. [ABSTRACT FROM AUTHOR]

Presents a list of research papers scheduled to be published in future issues of the journal 'Immunology,' as of September 1, 2003. Article on induction of apoptosis by interleukin-2-activated cytotoxic lymphocytes in squamous cell carcinoma cell line; Research paper on paradoxical effects of interleukin-10 on the maturation of murine myeloid dendritic cells; Paper on selective regulation of CD40 expression in murine dendritic cells by thiol antioxidants.

Introduces a series of papers related to immunology that will be published in the forth coming issues of the journal 'Immunology' as of June 1, 2003. Topic discussed by C. Tenger and X. Zhou; Authors of the paper discussing the effect of rat C-reactive protein on the autologous complement system; Topic discussed in the paper by Ian Downing, Claus Koch and David Kilpatrick.

A list of forthcoming papers related to immunology is presented. These include "Variable influences of iodine on the T-cell recognition of a single thyroglobulin epitope," by Hong Jiang, "Triacylated lipoproteins derived from Mycoplasma pneumoniae activate NF-jB through TLR1 and TLR2," by Takashi Shimizu, and "Disruption of Rxra gene in thymocytes and T lymphocytes modestly alters lymphocyte frequencies, proliferation, survival and Th1/Th2 balance," by Alexander Borowsky and Kevin Kent Lloyd.

A list of forthcoming papers related to immunology is presented. They include "Viral vector vaccines make memory T cells about malaria," by Arturo Reyes-Sandoval, John Harty, and Stephen Todryk, "Murine pregnancy leads to reduced proliferation of maternal thymocytes and decreased thymic emigration," by Allison Zoller, Frederick Schnell, and Gilbert Kersh, and "A role of MAP kinase and Ets-1 in the induction of IL-10 transcription by HIV-1 TaT," by James Li and Allan Lau.

Lists forthcoming research papers on immunology published in the journal "Immunology."

‘Natural’ opsonins to Salmonella typhimurium in serum from foetal and natal rats have been shown to be in part macroglobulins. The titre of these opsonins was shown to increase in the young natal animals. [ABSTRACT FROM AUTHOR]

Presents information on articles to be published in the forthcoming issues of the medical journal " Immunology," as of September 2003. Researchers who contributed an article on physical trauma of vaccination acts as a wake up call to dangers in the skin; Topic of the article contributed by researchers like Bettina Drescher, Torsten Witte, Reinhold Schmidt.

Lists articles to be published in the 'Immunology' periodical. Role of antigen presenting cells and interleukin-12 in the priming of antigen specific CD4[sup +] cells by immune stimulating complexes; Cell activation by monosaccharide lipid A analogs utilizing Toll-like receptor 4; Cytokine synthesis.

The article presents a list of forthcoming papers on immunology. Some of the papers include Cross-Linking of Neutrophil CD11b Results in Rapid Cell Surface Expression of Molecules Required for Antigen Presentation and T-Cell Activation," "Various Members of the Toll-Like Receptor Family Contribute to the Innate Immune Response of Human Epidermal Keratinocytes," "Identification and Characterisation of a Functional, Alternatively Spliced TLR7 and Genomic Disruption of TLR8 in Chickens," and "Introduction of Human Papillomavirus Type 16-Specific Immunologic Responses in a Normal and an HPV Infected Populations."

Summary: The Immune Epitope Database and Analysis Resource (IEDB) provides the scientific community with open access to epitope data, as well as epitope prediction and analysis tools. The IEDB houses the most extensive collection of experimentally validated B‐cell and T‐cell epitope data, sourced primarily from published literature by expert curation. The data procurement requires systematic identification, categorization, curation and quality‐checking processes. Here, we provide insights into these processes, with particular focus on the dividends they have paid in terms of attaining project milestones, as well as how objective analyses of our processes have identified opportunities for process optimization. These experiences are shared as a case study of the benefits of process implementation and review in biomedical big data, as well as to encourage idea‐sharing among players in this ever‐growing space. [ABSTRACT FROM AUTHOR]

Pulmonary fibrosis involves various types of immune cells and soluble mediators, including TGF‐β and IL‐35, a recently identified heterodimeric cytokine that belongs to the IL‐12 cytokine family. However, the effect of regulatory IL‐35 may play an important role in fibrotic diseases. The aim of this paper is to explore the immunoregulatory role of IL‐35 in the development of fibrosis in interstitial lung disease (ILD). To gain a better understanding of this issue, the concentrations of IL‐35 and different profibrotic cytokines in fibrotic (F‐ILD) and non‐fibrotic (NF‐ILD) patients by ELISA were compared to that of intracellular IL‐35 and IL‐17 on CD4+ T cells stimulated in the presence of BAL or with different ratios of recombinant IL‐35 (rIL‐35) and TGF‐β (rTGF‐β), which were evaluated by flow cytometry. We observed that BAL concentration of IL‐35 was lower in F patients (p < 0.001) and was negatively correlated with concentrations of TGF‐β (p < 0.001) and IL‐17 (p < 0.001). In supplemented cell cultures, BAL from NF but not F patients enhanced the percentage of IL‐35 + CD4+ T (p < 0.001) cells and decreased the percentage of IL‐17 + CD4+ T cells (p < 0.001). The percentage of IL‐35 + CD4+ T cells correlated positively with BAL concentration of IL‐35 (p = 0.02), but correlated negatively with BAL concentrations of IL‐17 (p = 0.007) and TGF‐β (p = 0.01). After adjusting the concentrations of recombinant cytokines to establish a TGF‐β: IL‐35 ratio of 1:4, an enhanced percentage of IL‐35 + CD4+ T cells (p < 0.001) but a decreased percentage of IL‐17 + CD4+ T cells (p < 0.001) was observed. After adding recombinant IL‐35 to the BAL from F patients until a 1:4 ratio of TGF‐β: IL‐35 was reached, a significantly increased percentage of IL‐35 + CD4+ T cells (p < 0.001) and a decreased percentage of IL‐17 + CD4+ T cells (p = 0.003) was found. These results suggest that IL‐35 may induce an anti‐fibrotic response, regulating the effect of TGF‐β and the inflammatory response on CD4+ T cells. In addition, the TGF‐β: IL‐35 ratio in BAL has been shown to be a potential biomarker to predict the outcome of F patients with ILD. [ABSTRACT FROM AUTHOR]

The article lists several papers related to immune system that are to be published in the December 2004 issue of the journal "Immunology." Some of the papers are "Phenotypic and Functional Heterogeneity of Porcine Blood Monocytes and Its Relation With Maturation," by Sonia Chamorro, Concepcion Revilla, Belen Alvarez, Fernando Alonso, Angel Ezquerra, Javier Dominguez; "Influence of Pathological Progression on the Balance Between Cellular and Humoral Immune Responses in Bovine Tuberculosis," Michael Welsh, Rodat Cunningham, David Corbett, R. Martyn Girvin, James McNair, Robin Skuce, David Bryson, John Pollock.

The article presents a list of forthcoming papers related to immunology. Some of the papers include "Inhibitory p41 Isoform of Invariant Chain and Its Potential Target Enzymes Cathepsins L and H in Distinct Populations of Macrophages in Human Lymph Nodes," by V. Zavašnik-Bergant, A. Schweiger, T. Bevec, R. Golouh, V. Turk, J. Kos, and " Echinococcus Multilocularis Proliferation in Mice and Respective Parasite 14-3-3 Gene Expression is Mainly Controlled by an CD4 + T cell Mediated Immune Response," by W. Dei, A. Waidvogel, M. Siles-Lucas, Bruno Gottistein.

Lists forthcoming research articles for the journal 'Immunology'.

Lists forthcoming papers on immunology published in the October 2005 issue of the journal "Immunology." "Relationship Between SPRY and B30.2 protei domains: Evolution of a Component of Immune Defense?" by David Rhodes, Bernard de Bono and John Trowsdale; "Putting the NK Cell in Its Place," by Geraldine O'Connor, Orla Hart and Clair Gardiner; "Tolerosome Induced Oral Tolerance Is MHC Restricted," by Esbjorn telemo, S. Ostman and M. Taube; Others.

Presents forthcoming papers in immunology published in previous issues.

Presents lists of forthcoming papers to be published in the journal of "Immunology."

Lists forthcoming papers on immunology, compiled as of November 2004. "T Cell Receptor-Induced Redistribution of Type 1 Protein Kinase A," by Wenhong Zhou and colleagues; "Phenotypic and Functional Heterogeneity of Porcine Blood Monocytes and Its Reaction with Maturation," by Sonia Chamorro and colleagues; "Purification, Characterization and Immunolocalization of Porcine Surfactant Protein D," by Tahir Razzaq and colleagues.

Presents forthcoming papers for the issue of "Immunology."

Presents a list of forthcoming papers on immunology which appeared in the July 2004 issue of "Immunology."

Lists names of various forthcoming research papers on immunology, published in the journal "Immunology" as of November 01, 2003. "Impact of cAMP on T cell Response to Type II Collagen" by scholars Patricia Ozegbe, Andrew Foey, Salman Ahmeda and Richard Williams; "Models of Signal Transduction Through the B Ccell Antigen Receptor" by scholars Roland Geisberger, Reto Crameri, Gernot Achatz; "B Cell Antigen Receptor Signaling in Lymphocyte Development" by scholars Leo D Wang and Marcus R. Clark.

The article lists forthcoming papers to be published in "Immunology," including "Dendritic Cells Modulated by Innate Immunity Improve Collagen-Induced Arthritis and Induce Treg in vivo," by Olivier Jaen, Sandrine Rullé, Natacha Bessis, Abokouo Zago, Marie-Christophe Boissier and Geraldine Falgarone; "The T-Cell Pool is Anergized in Patients with Multiple Sclerosis in Remission," by Moa E. Fransson, Lina S.E. Liljenfeldt, Jan Fagius, Thomas H. Tötterman and Angelica S.I. Loskog; and "The Mannose Receptor Binds Trichuris muris Excretory/Secretory Proteins But is Not Essential for Protective Immunity," by Matthew L. deSchoolmeester, Luisa Martinez-Pomares, Siamon Gordon and Kathryn J. Else.

The article lists forthcoming research papers related to immunology including "Tricks with tetramers: how to get the most from multimeric peptide-MHC," "Small changes in lymphocyte development and activation in mice by tissue-specific alteration of heparan sulphate" and "Alpha1 beta 1 integrin and IL-7 receptor upregulate the expression of RANKL in human T cells and enhance their osteoclastogenic function."

The article lists several forthcoming papers focusing on Immunology issues which includes "Differential Regulation of SOCS-1 Signaling in B and T Lymphocytes by HCV Core Protein," by Zhi Qiang Yao, Deborah Prayther, Christopher Trabue, Zhi Ping Dong, and Jonathan Moorman, "Defective T Cell Function Leading to Reduced Antibody Production in a Kleisin-Beta Mutant Mouse," by Katharine Gosling, Christopher Goodnow, Naresh Verma, and Aude Fahrer, and "The Modulatory Effects of Lipopolysaccharide Stimulated B Cells on Differential T Cell Polarization," by Hui Xu, Lip Nyin Liew, I Chun Kuo, Chiung Hui Huang, Denise Li-Meng Goh, and Kaw Yan Chua.

The article lists the forthcoming papers in immunology which includes "Apoptosis-induced inhibition of CD1d-mediated antigen presentation: different roles for caspases and signal transduction pathways," by Randy Brutkiewicz, Masood Khan, Venkataraman Sriram, Gourapura Renukaradhya, Wenjun Du, and Jacquelyn Gervay-Hague, "Dexamethasone transforms LPS-stimulated human blood myeloid dendritic cells (MDC) into MDC that prime IL-10 production in T-cells," by Jaap Kwekkeboom, Brenda Bosma, Herold Metselaar, Nicole Nagtzaam, Roel de Haan, Shanta Mancham, Luc van der Laan, and Ernst Kuipers, and "The immunomodulatory glycan LNFPIII initiates alternative activation of murine macrophages in vivo," by Olga Atochina, Akram Da'dara, Mirjam Walker, and Donald Harn.

The article presents a list of papers to be published in the journal including one on transgenic mice expressing a T cell, one on double-stranded RNA, and another on expression of chemokine or cytokine genes.

The article lists the forthcoming papers related to immunology which includes "Different types of in vitro generated human monocyte derived dendritic cells release exosomes of distinct phenotypes," by Sara Johnson and colleagues, "IL-21 activates human NK cells and modulates their surface receptor expression," by Kresten Skak and fellows, and "A subset of dendritic cells express joining chain (J-chain) protein," by Eva Källberg.

The article lists several papers related to immunology which includes "CD4+ T cell-dependent tumour rejection in an immune-privileged environment requires macrophages," by Dru Dace, Peter Chen, Jerry Niederkorn, "A simple immune system simulation reveals optimal movement and cell density parameters for successful target clearance," by Lindsay Nicholson and David Nicholson.

The article lists forthcoming papers including "Importance of N-linked gycosylation in the functional expression of murine CD1d," "Increased IL-10 production and Th2-skewing in the absence of 5-lipoxygenase," and "Neuropeptides activate human mast cell degranulation and chemokine production."

The article presents a list of forthcoming papers in the publication. These include "Dissection of spontaneous cytotoxicity by human intestinal intraepithelial lymphocytes: MIC on colon cancer triggers NKG2D-mediated lysis through fas ligand," "Myb proteins regulate expression of histone variant H2A.Z during thymocyte development," and "Importance of N-linked gycosylation in the functional expression of murine CD1d1."

A list of forthcoming papers related to immunology which are to be published is presented. They include "Prostaglandin E2 modulates dendric cell function during chlamydial genital infection," by Wei Liu and Kathleen Ann Kelly and "Dissection of spontaneous cytotoxicity by human intestinal intraepithelial lymphocytes: MIC on colon cancer triggers NKG2D-mediated lysis through Fas ligand," by Ellen Ebert and Veronika Groh.

The article lists the forthcoming papers on immunology which includes "Prostaglandin E2 modulates dendritic cell function during chlamydial genital infection," by Wei Liu and Kathleen Ann Kelly, "Role of endogenous 4-1BB in the development of systemic lupus erythematosus," by Dass Vinjay, Jae Choi and "Dissection of spontaneous cytotoxicity by human intestinal intraepithelial lymphocytes: MIC on colon cancer triggers NKG2D-mediated lysis through Fas ligand," by Ellen Ebert, Veronika Groh.

The article presents a list of the forthcoming papers related to immunology. They include "Induction of potent cellular immune response in mice by HCV NS3 protein with dsRNA," by Bo Jin and colleagues, "Live-attenuated influenza viruses as delivery vectors for Chlamydia vaccines," by Qing He and colleagues and "Autoantibodies profile in the experimental model of scleroderma induced by type V human collagen," by Maria Callado and colleagues.

A list of upcoming papers related to immunology is presented. They include "Mycobacterium tuberculosis HSP70 impairs maturation of dendritic cells from bone marrow precursors, induces IL-10 production and inhibits T-cell proliferation," "Triacylated lipoproteins derived from Mycoplasma pneumoniae activate NF-jB through TLR1 and TLR2," and " Sphingosine kinase inhibitor suppresses dendritic cell migration by regulating chemokine receptor expression and impairing p38 MAPK."

A list of papers and reports related to immunology is presented. They include "Studies on the interactions between C-reactive protein and complement proteins," "BMP2/4 signalling pathway components are expressed in the human thymus and inhibit early T-cell development" and "Marsupial CD1 is not orthologous to the eutherian isoforms and is a pseudogene in the opossum Monodelphis domestica."

A list of upcoming immunological papers to be published in a journal in presented. Among the studies are "CXCR3-Mediated T Cell Chemotaxis Involves Zap-70 and is Regulated by Signaling Through the T Cell Receptor," by Wasim A. Dar and Stuart J. Knechtle, and "Regulation of Human T Cell Homing Receptor Expression in Cutaneous Bacterial Infection," by Peter A. Sieling, Annaliza Legaspi, Thomas H. Rea and Robert L. Modlin.

The article presents a list of the journal's forthcoming papers related to immunology. They include "DNA and its cationic lipid complexes induce CpG motif-dependent activation of murine dendritic cells," "Differential type I interferon activation and susceptibility of dendritic cell populations to porcine arterivirus," and "Isolated lymphoid follicle maturation induces the development of follicular dendritic cells."

The article presents a list of forthcoming research papers related to immunology. They include "DNA and its cationic lipid complexes induce CpG motif-dependent activation of murine dendritic cells," "Mature dendritic cells pulsed with exosomes stimulate efficient cytotoxic T lymphocyte responses and antitumor immunity," and "Involvement of IL-10 in exhaustion of myeloid dendritic cells and rescue by CD40 stimulation."

A list of forthcoming papers to be published in the journal of "Immunology" is presented.

A list of papers related to the field of immunology is presented. These include "Lactoferrin decreases pollen antigen-induced allergic airway inflammation in a murine model of asthma," by Marian Kruzel and Istvan Boldogh, "Enhancement of CD8 T-cell function through modifying surface glycoproteins in young and old mice," by Amir Sadighi Akha and Richard Miller and "Essential role of neutrophils in anti-type II collagen antibody and LPS-induced arthritis," by Daisuke Tanaka and T. Shimozato.

The article presents a list of forthcoming papers related to immunology including "Epicutaneous Immunization Converts Subsequent and Established Antigen-specific Th1- to Th2-type responses," by Jessica Strid, Robin Callard and Stephan Strobel, "Variation and Infectivity Neutralization in Influenza," by Marcel Knossow and John Skehel and "Essential Role of Neutrophils in anti-type II collagen antibody and LPS-induced Arthritis," by Daisuke Tanaka, T. Kagari, H. Doi and T. Shimozato.

A list of forthcoming papers of the journal "Immunology" is presented. Spontaneous Scratching Behaviour in DS-Nh Mice As a Possible Model for Pruritus in Atopic Dermatitis," "Role of BAFF and APRIL in Human B-Cell Chronic Lymphocytic Leukaemia," "Anti-idiotype Antibody Induced Cellular Immunity in Mice Transgenic for Human Carcinoembryonic Antigen."