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1. The T-cell response to haptenated insulins II. THE ANTIBODY RESPONSE.

Author

Florys, M., Wallace, G.R., Oettel, K., and Chain, B.M.

Subjects
*T cells, *INSULIN, *IMMUNOGLOBULINS, *LYMPHOCYTES, *GLYCINE, *CELL proliferation
Abstract

As described in an accompanying paper, trinitrophenyl (TNP) modification of pork insulin (PI) at the A1 glycine position allows this molecule to stimulate a proliferative response in H-2b (B10) mice. We now show that this antigen stimulates low IgG responses in the same strain of mice. Our results show that T-cell help and proliferation may therefore be regulated independently. [ABSTRACT FROM AUTHOR]

Published
1989