1. Epidemiology and resistance pattern of bacterial isolates among cancer patients in a Tertiary Care Oncology Centre in North India.
- Author
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U., Batra, P., Goyal, P., Jain, A., Upadhyay, N., Sachdeva, M., Agarwal, D., Bhurani, V., Talwar, S. K., Gupta, D. C., Doval, Batra, U, Goyal, P, Jain, P, Upadhyay, A, Sachdeva, N, Agarwal, M, Bhurani, D, Talwar, V, Gupta, S K, and Doval, D C
- Subjects
BACTERIAL diseases ,CANCER treatment ,EPIDEMIOLOGY ,CEPHALOSPORINS ,FLUOROQUINOLONES - Abstract
Objectives: To examine the epidemiology of microbiologically documented bacterial infection and the resistance pattern, among cancer patients undergoing treatment at RGCIRC, Delhi.Design and Setting: Retrospective observational study in which culture reports obtained over 1 year in 2013, were analyzed.Results: 13329 cultures were obtained over 1 year in 2013 and were analyzed. 23.6 % samples showed positive culture with majority being gram negative isolates (67.9 %). E. coli was the commonest gram negative isolate (49.4%) followed by klebsella (29.7%) and Staph. aureus was the commonest gram positive isolate. There was high incidence of ESBL in blood and urine (87.2% & 88.5%) and BLBLI were also high (78% & 83.9%). Carbapenem resistance was comparatively low (10%) and colistin sensitivity was quiet high (> 95%).Conclusions: Prevalence of MRSA and VRE in our institute is very less, whereas prevalence of ESBLs and BLBLI isolates amongst gram negative infections is around 80%. Gram negative isolates had poor sensitivity to cephalosporins and fluoroquinolones. [ABSTRACT FROM AUTHOR]- Published
- 2016
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