1. Cytokeratin-positive primitive neuroectodermal tumor of the prostate: case report and review of literature
- Author
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Ibrahim Al Haddabi, Maiya Al Bahri, and Ikram A. Burney
- Subjects
Microbiology (medical) ,Male ,Pathology ,medicine.medical_specialty ,CD99 ,lcsh:QR1-502 ,lcsh:Microbiology ,Pathology and Forensic Medicine ,Cytokeratin ,Young Adult ,Prostate ,primitive neuroectodermal tumor ,lcsh:Pathology ,medicine ,Biomarkers, Tumor ,Humans ,Neuroectodermal Tumors, Primitive ,In Situ Hybridization, Fluorescence ,Gene Rearrangement ,Microscopy ,medicine.diagnostic_test ,business.industry ,Histocytochemistry ,Ewing′s sarcoma ,Ewing's sarcoma ,Prostatic Neoplasms ,General Medicine ,medicine.disease ,Immunohistochemistry ,medicine.anatomical_structure ,Primitive neuroectodermal tumor ,poorly differentiated synovial sarcoma ,Sarcoma ,business ,Tomography, X-Ray Computed ,prostate gland ,Chromosome 22 ,lcsh:RB1-214 ,Fluorescence in situ hybridization - Abstract
Ewing′s sarcoma/primitive neuroectodermal tumor (ES/PNET) of the prostate is extremely rare. Here, we report a case of ES/PNET of prostate in a 24-year-old man presenting with dysuria and pelvic discomfort. Computed tomography scan revealed a heterogeneous mass involving the prostate without evidence of distant metastases. Histologically, the tumor was composed of small round blue cells strongly and diffusely positive for CD99 and epithelial markers. Fluorescence in situ hybridization confirmed rearrangement of the Ewing′s sarcoma region on chromosome 22.
- Published
- 2013