1. Effects of single dose methylprednisolone on patient recovery after cardiopulmonary bypass
- Author
-
Sudesh Sharda, Ram Prasad Kaushal, Sanjay Ranganath Pawar, Amber Malhotra, Praveen Sharma, and M. C. Songra
- Subjects
Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,business.industry ,Cardiac index ,Atrial fibrillation ,medicine.disease ,Intensive care unit ,law.invention ,Surgery ,Cardiac surgery ,Postoperative fever ,Methylprednisolone ,law ,Cardiothoracic surgery ,Anesthesia ,Cardiopulmonary bypass ,medicine ,Cardiology and Cardiovascular Medicine ,business ,medicine.drug - Abstract
Ischaemic reperfusion injury, systemic inflammatory response and multi-organ dysfunction are not infrequent following Cardiopulmonary Bypass (CPB). We investigated the role of methylprednisolone in minimizing this state. Hundred consecutive patients undergoing elective single heart valve replacement surgery were randomized to receive methylprednisolone 30 mg/kg (M group) or placebo (P group) after induction of anaesthesia. Data were analyzed using the‘t’ test and Fischer test. The cardiac indices in the M and P group were 2.79 ± 0.13 L/min/m2 and 2.52 ± 0.26 L/min/m2 respectively (p
- Published
- 2012
- Full Text
- View/download PDF