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The accuracy of the data class is very important in classification with a machine learning approach. The more accurate the existing data sets and classes, the better the output generated by machine learning. In fact, classification can experience imbalance class data in which each class does not have the same portion of the data set it has. The existence of data imbalance will affect the classification accuracy. One of the easiest ways to correct imbalanced data classes is to balance it. This study aims to explore the problem of data class imbalance in the medium case dataset and to address the imbalance of data classes as well. The Synthetic Minority Over-Sampling Technique (SMOTE) method is used to overcome the problem of class imbalance in obesity status in Indonesia 2013 Basic Health Research (RISKESDAS). The results show that the number of obese class (13.9%) and non-obese class (84.6%). This means that there is an imbalance in the data class with moderate criteria. Moreover, SMOTE with over-sampling 600% can improve the level of minor classes (obesity). As consequence, the classes of obesity status balanced. Therefore, SMOTE technique was better compared to without SMOTE in exploring the obesity status of Indonesia RISKESDAS 2013.

In Indonesia malaria is found to be widespread in all islands with varying degrees and severity of infection. Based on the Annual of Parasite Incidence (API) in Eastern Indonesia, Malaria is a disease that has a high incidence rate. The three provinces with the highest APIs are Papua (42.64%), West Papua (38.44%) and East Nusa Tenggara (16.37%). Spatial aspects are considered important to be studied because the spread of disease through mosquitoes is strongly influenced by fluctuating climate. The purpose of this study is to determine the potential factors that influence the incidence of Malaria disease in the province of Papua in 2013 by looking at aspects that are the focus of attention in spatial epidemiology. The methods used in analyzing the area are Simultaneous Autoregressive (SAR) and Conditional Autoregressive (CAR) models with a spatial weighting matrix up to second order. The result shows the average monthly wind velocity, average monthly rainfall, and malaria treatment with government program drugs by getting ACT drugs are substantial factors in determining the incidence number of Malaria in Papua based on the lowest AIC value for the second-order of CAR model. While the SAR model, in this case, has no spatial influence. By knowing the potential factors that influence the incidence of malaria, the Papua Province through the Health Office can take more effective preventive measures to reduce the number of malaria incidents.

Diabetes mellitus (DM) is one of the chronic and deadly diseases that are widely observed in various countries today. This disease continues and is increasing to a very alarming stage. This study aims to identify and see the relationship between factors that influence DM disease. The method used in this research is C4.5 algorithm which is one of the algorithms used to make predictive classifications. Classification is one of the processes in data mining that aims to find patterns in relatively large data that use the representations in the form of decision trees. This method is applied to data from medical records of patients with DM in 2014-2018 taken from the Hasanuddin University Teaching Hospital. The results obtained indicate that there are four factors that influence the prediction of a patient's DM status namely; Fasting Blood Glucose (GDP), LDL Cholesterol, Triglycerides, and Body Weight.