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1. Epidemiology, management and outcome of varicella in pregnancy: a 20-year experience at the Tuscany Reference Centre for Infectious Diseases in Pregnancy.

Author

Trotta M, Borchi B, Niccolai A, Venturini E, Giaché S, Sterrantino G, Colao MG, Rossolini GM, Bartoloni A, and Zammarchi L

Subjects
Adolescent, Adult, Chickenpox immunology, Female, Humans, Infant, Newborn, Italy epidemiology, Middle Aged, Pregnancy, Retrospective Studies, Risk, Young Adult, Chickenpox epidemiology, Herpesvirus 3, Human immunology, Immune Sera administration & dosage, Pregnancy Outcome epidemiology
Abstract

Data from 215 pregnant women exposed to varicella and 276 with varicella observed at the Tuscany Reference Center for Infectious Diseases in Pregnancy, Florence, Italy, in the period 1997-2016 were retrospectively collected. The risk of developing varicella was lower in exposed women who received varicella zoster immunoglobulin compared with those who did not receive it [42% (21 of 50) vs 72% (13 of 18); p = 0.0263]. Typical congenital varicella syndrome was observed in 1.56% of fetuses/neonates born from pregnant women with varicella.

Published
2018
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