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Please cite this paper as: Higa et al. (2012) Role of neuraminidase inhibitor chemoprophylaxis in controlling nosocomial influenza: an observational study. Influenza and Other Respiratory Viruses 6(4), 299-303. Background An influenza outbreak might result in disruption of services at acute care setting hospitals. Objectives In this study, we retrospectively evaluated the use of neuraminidase inhibitor chemoprophylaxis for prevention of nosocomial spread of influenza in a university hospital. Patients/Methods During the 3-year study period, 202 index cases of influenza [30 hospitalized patients and 172 healthcare workers (HCW)] and 762 individuals who had had close contact with the index cases (248 hospitalized patients and 514 HCW) were identified. Of these contacts, 416 received neuraminidase inhibitor chemoprophylaxis. Results When both the index cases and the close contacts were hospitalized patients, the incidence of influenza was lower among the close contacts who received chemoprophylaxis than among those who did not (odds ratio, 0·07; confidence interval, 0·01-0·49; P = 0·012). In contrast, when the index cases were HCW, the incidence of influenza was not different between close contacts who did or did not receive chemoprophylaxis. Conclusions This study suggests that chemoprophylaxis might be useful to prevent nosocomial spread of infection between hospitalized patients. [ABSTRACT FROM AUTHOR]

Objective In this study, we describe the chest computed tomography findings of influenza virus-associated pneumonia in adult patients. Methods Our retrospective study included 12 adult patients who had proven influenza virus - associated pneumonia. Results Out of 12 patients, six were diagnosed as having pure influenza virus pneumonia, five as having bronchopneumonia caused by bacteria associated with influenza A infection, and one as having a cryptogenic organizing pneumonia associated with influenza A infection. Conclusion Radiographic findings of influenza virus pneumonia in adult patients consist of ground-glass attenuation. Localized patchy consolidations were observed in cases of bronchopneumonia. [ABSTRACT FROM AUTHOR]

Please cite this paper as: Sunagawa et al. (2012) Single-dose inhaled laninamivir: registered in Japan and its potential role in control of influenza epidemics. Influenza and Other Respiratory Viruses DOI: 10.1111/j.1750-2659.2012.00351.x. [ABSTRACT FROM AUTHOR]

Please cite this paper as: Fujita et al. (2012) Hamman-Rich syndrome revisited: How to avoid misdiagnosis. Influenza and Other Respiratory Viruses. DOI: 10.1111/j.1750-2659.2012.00353.x. [ABSTRACT FROM AUTHOR]