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Your search keyword '"Hejl, Michaela"' showing total 10 results
Start Over Author "Hejl, Michaela" Journal inorganic chemistry
10 results on '"Hejl, Michaela"'

1. Tridentate 3-Substituted Naphthoquinone Ruthenium Arene Complexes: Synthesis, Characterization, Aqueous Behavior, and Theoretical and Biological Studies

Author

Geisler, Heiko, primary, Westermayr, Julia, additional, Cseh, Klaudia, additional, Wenisch, Dominik, additional, Fuchs, Valentin, additional, Harringer, Sophia, additional, Plutzar, Sarah, additional, Gajic, Natalie, additional, Hejl, Michaela, additional, Jakupec, Michael A., additional, Marquetand, Philipp, additional, and Kandioller, Wolfgang, additional

Published
2021
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2. Rollover Cyclometalated Bipyridine Platinum Complexes as Potent Anticancer Agents: Impact of the Ancillary Ligands on the Mode of Action

Author

Babak, Maria V., primary, Pfaffeneder-Kmen, Martin, additional, Meier-Menches, Samuel M., additional, Legina, Maria S., additional, Theiner, Sarah, additional, Licona, Cynthia, additional, Orvain, Christophe, additional, Hejl, Michaela, additional, Hanif, Muhammad, additional, Jakupec, Michael A., additional, Keppler, Bernhard K., additional, Gaiddon, Christian, additional, and Hartinger, Christian G., additional

Published
2018
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3. [[Os.sup.IV][Cl.sub.5](hazole)]- complexes: synthesis, structure, spectroscopic properties, and antiproliferative activity

Author

Bochel, Gabriel E., Stepanenko, Iryna N., Hejl, Michaela, Jakupec, Michael A., Arion, Vladimir B., and Keppler, Bernhard K.

Subjects
Carcinoma -- Research, Cancer -- Research, Hydrolysis -- Analysis, Infrared spectroscopy -- Usage, Osmium -- Chemical properties, Osmium -- Structure, Pyrazoles -- Chemical properties, Pyrazoles -- Structure, X-ray crystallography -- Usage, Chemistry
Published
2009

10. En Route to Osmium Analogues of KP1019: Synthesis, Structure, Spectroscopic Properties and Antiproliferative Activity of trans-[OSIV CI4(Hazole)2].

Author

Büüchel, Gabriel E., Stepanenko, Iryna N., Hejl, Michaela, Jakupec, Michael A., Keppler, Bernhard K., and Arion, Vladimir B.

Subjects
*BIOSYNTHESIS, *METAL ions, *CRYSTALLOGRAPHY, *VOLTAMMETRY, *CELL lines, *CANCER
Abstract

By controlled Anderson type rearrangement reactions complexes of the general formula trans-[OsIVCl4(Hazole)2], where Hazole = 1H-pyrazole, 2H-indazole, 1H-imidazole, and 1H-benzimidazole, have been synthesized. Note that 2H-indazole tautomer stabilization in trans-[OsIVCl4(2H-indazole)2] is unprecedented in coordination chemistry of indazole. The metal ion in these compounds possesses the same coordination environment as ruthenium(III) in (H2ind)[RuIIICl4(Hind)2], where Hind = 1H-indazole, (KP1019), an investigational anticancer drug in phase I clinical trials. These osmium(IV) complexes are appropriate precursors for the synthesis of osmium(III) analogues of KP1019. In addition the formation of an adduct of trans-[OsIVCl4(Hpz)2] with cucurbit[7]uril is described. The compounds have been comprehensively characterized by elemental analysis, EI and ESI mass spectrometry, spectroscopy (IR, UV-vis, 1D and 2D NMR), cyclic voltammetry, and X-ray crystallography. Their antiproliferative acitivity in the human cancer cell lines CH1 (ovarian carcinoma), A549 (nonsmall cell lung carcinoma), and SW480 (colon carcinoma) is reported. [ABSTRACT FROM AUTHOR]

Published
2011
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