1. The Effect of High-concentration Insulin Glarigine on the Quality of Life of Patients with Type 2 Diabetes Mellitus: A Pre-post Study (HIGH-QOL STUDY)
- Author
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Miho Tsuruo, Kenji Kamiuchi, Hideaki Sawaki, Akiko Suganuma, Moritsugu Kimura, Masao Toyoda, Naoki Sakane, Satoshi Kawashima, Kensou Osawa, Takashi Murata, Ryuji Kouyama, Ken Kato, Kohshi Narasaki, Atsuhito Tone, and Tomokazu Watanabe
- Subjects
Adult ,Male ,medicine.medical_specialty ,concentration ,Psychometrics ,Visual analogue scale ,type 2 diabetes mellitus ,medicine.medical_treatment ,Drug Compounding ,Injections, Subcutaneous ,Insulin Glargine ,Pain ,030204 cardiovascular system & hematology ,Drug Administration Schedule ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,law ,Internal medicine ,Internal Medicine ,medicine ,Humans ,Hypoglycemic Agents ,Aged ,Pain Measurement ,High concentration ,Aged, 80 and over ,Pain score ,business.industry ,Insulin glargine ,Insulin ,Significant difference ,Type 2 Diabetes Mellitus ,Patient Preference ,General Medicine ,Middle Aged ,Diabetes Mellitus, Type 2 ,injection ,Quality of Life ,030211 gastroenterology & hepatology ,Female ,Original Article ,business ,medicine.drug - Abstract
Objective We compared the pain accompanying the injection of high-concentration (300 units/mL) insulin glargine (U300G) with that accompanying the injection of conventional (100 units/mL) insulin glargine (U100G). Methods U100G was switched to U300G at basically the same dosage. Visual analog scales were used to assess the quality of life (QOL). The primary outcome was the change in the pain accompanying injections in those using ≥30 units of U100G compared with those using
- Published
- 2019