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Your search keyword '"Ayonrinde, Oyekoya T"' showing total 2 results
Start Over Author "Ayonrinde, Oyekoya T" Topic old age Publication Year Range Last 3 years Journal internal medicine journal
2 results on '"Ayonrinde, Oyekoya T"'

1. Prior oral proton‐pump inhibitor use is associated with reduced severity of aspirin‐related upper gastrointestinal bleeding in older people.

Author

Ayonrinde, Oyekoya T., Walldorf, Natasha, Chan, Nicholas, Foo, Nathanael Y., Kulkarni, Tithi, Olynyk, John K., and Sanfilippo, Frank M.

Subjects
*GASTROINTESTINAL hemorrhage, *ORAL drug administration, *ENDOSCOPIC surgery, *RETROSPECTIVE studies, *PROTON pump inhibitors, *SEVERITY of illness index, *COMPARATIVE studies, *RECTUM, *ASPIRIN, *HEMATEMESIS, *DESCRIPTIVE statistics, *PEPTIC ulcer, *DATA analysis software, *ENDOSCOPY, *DISEASE risk factors, *OLD age
Abstract

Low‐dose aspirin is commonly used for primary or secondary prophylaxis against cardiovascular disease in older people. However, the potential risk of upper gastrointestinal (UGI) ulceration and bleeding associated with low‐dose aspirin use is often not appreciated by prescribers and older consumers. Among 133 serial patients with UGI bleeding, aspirin‐users aged ≥70 years had a ninefold increased likelihood of overt UGI bleeding compared with non‐users, reducing by 90% in regular proton‐pump inhibitor users (adjusted odds ratio 0.10). We recommend risk‐versus‐benefit discussions when recommending aspirin to older people. [ABSTRACT FROM AUTHOR]

Published
2022
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2. Prescribing aspirin to older people – where is the line between cardiovascular benefit and upper gastrointestinal bleeding risk?

Author

Ayonrinde, Oyekoya T., Sanfilippo, Frank M., and Schultz, Carl

Subjects
*COMBINATION drug therapy, *MAJOR adverse cardiovascular events, *GASTROINTESTINAL hemorrhage, *ASPIRIN, *PLATELET aggregation inhibitors, *CORONARY artery disease, *DISEASE risk factors, *OLD age
Abstract

The article talks about Non-variceal upper gastrointestinal bleeding (UGIB) resulting from gastro duodenal ulcer haemorrhage, which is a common cause of hospitalisation in middle-aged and older Australians. Mentions aspirin is the most common antiplatelet agent used at low dose for the prevention of cardiovascular events; however, low-dose enteric-coated aspirin has not fulfilled the expectation of reducing gastroduodenal ulceration and bleeding.

Published
2022
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