18 results on '"Januszewski, A"'
Search Results
2. No relationship between socioeconomic status, education level and development and progression of diabetic retinopathy in type 2 diabetes: a FIELD trial substudy.
- Author
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Rao, Ben, Januszewski, Andrzej S., Brazionis, Laima, O'Connell, Rachel, Aryal, Nanda, Shimmin, Georgia, O'Day, Justin, Mitchell, Paul, Colman, Peter G., Keech, Anthony C., and Jenkins, Alicia J
- Subjects
- *
DISEASE progression , *TYPE 2 diabetes , *RISK assessment , *SOCIAL classes , *DESCRIPTIVE statistics , *DIABETIC retinopathy , *DATA analysis software , *EDUCATIONAL attainment , *DISEASE risk factors , *DISEASE complications - Abstract
In 6002 Australian adults with type 2 diabetes and a median 5‐year follow‐up in the FIELD (Fenofibrate Intervention and Event Lowering in Diabetes) trial, baseline socioeconomic status (SES) and self‐reported education level were not related to development of on‐trial sight‐threatening diabetic retinopathy. Similarly, in a retinal photography substudy (n = 549), two‐step diabetic retinopathy progression was not related to SES or education. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
3. Point‐of‐care testing of <scp>HbA1c</scp> , renal function and lipids in remote or disadvantaged regions
- Author
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Lena Handrinos, Alicia J. Jenkins, Elisabeth R. Trimble, Neil Donelan, Paul F. Williams, and Andrzej S. Januszewski
- Subjects
Glycated Hemoglobin ,medicine.medical_specialty ,Native Hawaiian or Other Pacific Islander ,Emergency management ,business.industry ,Point-of-care testing ,Australia ,Indigenous health ,Community screening ,Lipids ,Vulnerable Populations ,Indigenous ,Disadvantaged ,Health services ,Point-of-Care Testing ,Diabetes management ,Family medicine ,Internal Medicine ,Health Services, Indigenous ,Humans ,Medicine ,Rural Health Services ,business - Abstract
For optimal diabetes management HbA1c, lipid and renal function measurements are key. Suitable point-of-care systems can provide such data in remote areas, diabetes camps, disaster relief, small community hospitals and in community screening days in disadvantaged regions. Some systems are currently used in Australian rural, remote and indigenous health services.
- Published
- 2020
- Full Text
- View/download PDF
4. Time to research Australian physician-researchers
- Author
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Traill, C. L., Januszewski, A. S., Larkins, R., Keech, A. C., and Jenkins, A. J.
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- 2016
- Full Text
- View/download PDF
5. Time to research Australian female physician-researchers
- Author
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Traill, C. L., Januszewski, A. S., Larkins, R. G., Keech, A. C., and Jenkins, A. J.
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- 2016
- Full Text
- View/download PDF
6. Attractions and barriers to Australian physician-researcher careers
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Caroline L Traill, Joanna M. Z. Mills, Andrzej S. Januszewski, Bruce G. Robinson, Anthony C Keech, and Alicia J. Jenkins
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Medical education ,Job insecurity ,business.industry ,education ,Medical school ,030204 cardiovascular system & hematology ,Medical research ,03 medical and health sciences ,Work time ,Human health ,0302 clinical medicine ,Respondent ,Internal Medicine ,Medicine ,030212 general & internal medicine ,Salary ,business ,Diversity (business) - Abstract
Background There is a global concern that physician-researchers are 'a dying breed'. Recent studies of clinical career choices of Australian medical students and doctors have signalled the rising age of medical graduates, generational shifts in work-life attitudes and increased proportion of female graduates. There are scant data regarding Australian physician-researchers. Aims To develop and utilise a questionnaire determining respondent characteristics and 'push' and 'pull' factors for medical graduates to incorporate research into their careers. Methods We developed and administered an 88-item online survey, including quantitative and qualitative questions, to medical students, faculty and alumni of Sydney Medical School, The University of Sydney, asking about their medical career, research experience and interest and reasons for doing or not doing medical research. Responses to all 74 quantitative questions are reported here. Results Data from 427 respondents (44% female; mean ± standard deviation age 38 ± 13 years; 56% completed or undertaking a PhD) were analysed. Attractions of research included a desire to improve human health, intellectual stimulation and career diversity. Barriers included low funding rates, job insecurity and low salaries. Although few were prepared to undertake or recommend full-time research, 71% would recommend part-time research. Respondents perceived a smaller-than-actual gap between clinical and research salaries, and if comparable (75-100% of a clinician's) salaries were available, 89% would like to spend 21-60% of their work time undertaking research. Conclusion Many Australian medical students and doctors are interested in research, especially part time. Perceived obstacles include job insecurity, low funding rates and salary. Respondents underestimated clinical and research salary differences.
- Published
- 2019
- Full Text
- View/download PDF
7. Suboptimal behaviour and knowledge regarding overnight glycaemia in adults with type 1 diabetes is common
- Author
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Johnny Ludvigsson, David N O'Neal, Gregory R. Fulcher, Rachel T. McGrath, Christina R. Larsson, Richard J MacIsaac, Anthony C Keech, Glenn M. Ward, Alicia J. Jenkins, and Andrzej S. Januszewski
- Subjects
Insulin pump ,Type 1 diabetes ,medicine.medical_specialty ,business.industry ,Insulin ,medicine.medical_treatment ,030209 endocrinology & metabolism ,Hypoglycemia ,medicine.disease ,Bedtime ,03 medical and health sciences ,0302 clinical medicine ,Metabolic control analysis ,Diabetes mellitus ,Internal medicine ,Internal Medicine ,medicine ,030212 general & internal medicine ,Ketosis ,business - Abstract
BACKGROUND: In people with type 1 diabetes (T1D), nocturnal hypoglycaemia (NH) can be slept through and can cause seizures, arrhythmias and death. Hypoglycaemia avoidance can induce hyperglycaemia and ketosis. Patient behaviour impacts clinical outcomes and may be changed by education. AIM: To develop and utilise a survey to evaluate patient self-management of overnight glycaemia in adults with T1D. METHODS: Adults with T1D attending two Australian tertiary referral diabetes clinics completed a survey about their diabetes self-management and glycaemic control, including responses to hypothetical pre-bed blood glucose (BG) levels (4-20 mmol/L). Statistical analyses included t-tests, Chi square tests and ANOVA with significance considered at P < 0.05. RESULTS: There were 205 participants (103 females), with a mean (SD) age of 41 (17) years, T1D duration of 20 (16) years, HbA1c of 7.8(1.4)%, (61.3(8.2) mmol/mol), 38% on insulin pump therapy (CSII) and 36% with impaired hypoglycaemia awareness (IHA). Mean (SD) number of BG tests/day was 5.4 (2.7). Patients set higher BG target levels at bedtime and overnight: 7.5(1.4) and 7.1(1.3) mmol/L, respectively, compared to daytime (6.9(1.0); P < 0.0001 and P = 0.002 respectively). Only 36% of participants reported treating nocturnal hypoglycaemia (NH) with the recommended refined, then complex, carbohydrate. Only 28% of patients made safe choices in all bedtime BG scenarios, with higher rates for CSII users, P = 0.0005. Further education was desired by 32% of respondents, with higher rates in those with (44%) versus without IHA (25%), P = 0.006. CONCLUSIONS: Many adults with T1D have suboptimal knowledge and behaviour regarding overnight BG self-management. A survey, piloted herein, may facilitate the identification of patients who could benefit from further education.
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- 2018
- Full Text
- View/download PDF
8. Point‐of‐care testing of HbA1c , renal function and lipids in remote or disadvantaged regions
- Author
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Handrinos, Lena, primary, Januszewski, Andrzej S., additional, Trimble, Elisabeth, additional, Donelan, Neil, additional, Williams, Paul, additional, and Jenkins, Alicia J., additional
- Published
- 2020
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- View/download PDF
9. Fenofibrate, which reduces risk of sight‐threatening diabetic retinopathy in type 2 diabetes, is associated with early narrowing of retinal venules: a FIELD trial substudy.
- Author
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Quinn, Nicola, Januszewski, Andrzej S., Brazionis, Laima, O'Connell, Rachel, Aryal, Nanda, O'Day, Justin, Scott, Russell, Mitchell, Paul, Jenkins, Alicia J., and Keech, Anthony C.
- Subjects
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RETINAL vein , *RETINA , *FENOFIBRATE , *TYPE 2 diabetes , *DIABETIC retinopathy , *DISEASE complications - Abstract
Retinal vessel calibre metrics were evaluated at baseline and 2 years in a FIELD substudy (n = 208). Central retinal venule calibre was significantly reduced by fenofibrate and unchanged by placebo. Arteriole metrics did not change. Larger studies relating retinal vessel calibre to future diabetes complications and response to therapy are merited. [ABSTRACT FROM AUTHOR]
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- 2022
- Full Text
- View/download PDF
10. Time to research Australian physician-researchers
- Author
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Caroline L Traill, Richard G Larkins, Anthony C Keech, Alicia J. Jenkins, and Andrzej S. Januszewski
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National health ,medicine.medical_specialty ,Occupational group ,020205 medical informatics ,business.industry ,education ,Specialty ,Medical school ,02 engineering and technology ,Medical practitioner ,Categorical grant ,03 medical and health sciences ,0302 clinical medicine ,Nursing ,Median time ,Family medicine ,Public hospital ,0202 electrical engineering, electronic engineering, information engineering ,Internal Medicine ,medicine ,030212 general & internal medicine ,business ,health care economics and organizations - Abstract
BACKGROUND Concerns have been expressed 'that the physician-researcher is a dying breed'. As yet there are few Australian data. AIMS To compare over time: (i) research progress of Sydney Medical School (SMS) medical practitioner - PhD awardees; (ii) National Health and Medical Research Council (NHMRC) project grant success rates for physician-researchers; and (iii) compare current NHMRC, NSW University and NSW Public Hospital pay scales for physician-researchers. METHODS We evaluated 303 medical practitioners awarded a University of Sydney/SMS PhD in 1989-2012 and their publications. We assessed 1990-2014 NHMRC grants to physicians and non-physicians (nationally) and compared physician salaries from NHMRC, the University of Sydney and NSW public hospitals. RESULTS SMS PhD completions by clinicians increased ≈2.4-fold since 1989, with a recent decline, whilst non-medical PhD awardees rose 10-fold. The median time of PhD award after medical degree completion was stable at 13 years. A lower percentage of the more recent physician-researchers had completed specialty training at PhD award (34% in 2011-2012 vs 71% in 1989-1990, P = 0.017). Publication rates were stable, but low. Although NHMRC funding increased >10-fold since 1990, national project grant success rates declined (35% in 1990, 17% in 2013 and 15% in 2014, P < 0.0001), with physician-led funded grants declining from 29% in 1989 to 21% in 2013, P = 0.002. Current NHMRC and University salaries are less than comparable-stage public hospital salaries. CONCLUSION Since 1989, more medical graduates are completing SMS PhDs, although more often prior to completing clinical Fellowships, and many have ongoing, albeit low, research activity. Nationally NHMRC project grant success rates have declined significantly, as has the proportion of funded physician-led projects. Medical practitioner salaries from NHMRC and from Universities are less than in public hospitals. The Australian physician-researcher is at-risk. Knowledge and actions are needed to protect our medical research capacity.
- Published
- 2016
- Full Text
- View/download PDF
11. Time to research Australian female physician-researchers
- Author
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Caroline L Traill, Richard G Larkins, Andrzej S. Januszewski, Anthony C Keech, and Alicia J. Jenkins
- Subjects
National health ,Gerontology ,medicine.medical_specialty ,Occupational group ,business.industry ,education ,Alternative medicine ,Scopus ,Medical school ,030204 cardiovascular system & hematology ,Categorical grant ,03 medical and health sciences ,0302 clinical medicine ,Workforce ,Internal Medicine ,medicine ,030212 general & internal medicine ,business ,health care economics and organizations - Abstract
BACKGROUND Given the concerns that physician-researchers are 'at risk', and ≈50% of Australian medical students are female, the evaluation of female physician-researchers is important. AIMS To compare over time (i) research-related metrics of male and female physician-researchers from Sydney Medical School; and (ii) National Health and Medical Research Council (NHMRC) Project grant leadership by gender. METHODS The Sydney Medical School (SMS) PhD award lists from 1989 to 2012 were cross-referenced with the Australian Health Practitioner Regulation Agency database, and registered medical practitioners were searched for in the Scopus database for publications and H-indexes. The gender of medical-practitioner Chief Investigator A (CIA) in Australia on funded NHMRC Project grants in 1990 to 2014 was also compared. RESULTS Of the medical practitioners awarded University of Sydney PhD, females increased from 14 to 55% in 1989-1990 and 2009-2010 and decreased to 38% in 2011-2012 (overall increase, P = 0.047). PhD award timings relative to MBBS and clinical fellowship completions were similar for both genders (P > 0.05). Post-PhD, as many women as men publish and have similar H-indexes, but women publish fewer papers (0.7 vs 1.0 publications per year, P = 0.028). On medical practitioner-led, funded NHMRC project grants between 1999 and 2014, female CIA increased from 7.5 to 19.5%, P
- Published
- 2016
- Full Text
- View/download PDF
12. Attractions and barriers to Australian physician-researcher careers
- Author
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Joanna M Z, Mills, Andrzej S, Januszewski, Bruce G, Robinson, Caroline L, Traill, Alicia J, Jenkins, and Anthony C, Keech
- Subjects
Adult ,Male ,Biomedical Research ,Students, Medical ,Career Choice ,Attitude of Health Personnel ,Salaries and Fringe Benefits ,Australia ,Middle Aged ,Research Personnel ,Physicians ,Surveys and Questionnaires ,Financial Support ,Humans ,Female ,Schools, Medical - Abstract
There is a global concern that physician-researchers are 'a dying breed'. Recent studies of clinical career choices of Australian medical students and doctors have signalled the rising age of medical graduates, generational shifts in work-life attitudes and increased proportion of female graduates. There are scant data regarding Australian physician-researchers.To develop and utilise a questionnaire determining respondent characteristics and 'push' and 'pull' factors for medical graduates to incorporate research into their careers.We developed and administered an 88-item online survey, including quantitative and qualitative questions, to medical students, faculty and alumni of Sydney Medical School, The University of Sydney, asking about their medical career, research experience and interest and reasons for doing or not doing medical research. Responses to all 74 quantitative questions are reported here.Data from 427 respondents (44% female; mean ± standard deviation age 38 ± 13 years; 56% completed or undertaking a PhD) were analysed. Attractions of research included a desire to improve human health, intellectual stimulation and career diversity. Barriers included low funding rates, job insecurity and low salaries. Although few were prepared to undertake or recommend full-time research, 71% would recommend part-time research. Respondents perceived a smaller-than-actual gap between clinical and research salaries, and if comparable (75-100% of a clinician's) salaries were available, 89% would like to spend 21-60% of their work time undertaking research.Many Australian medical students and doctors are interested in research, especially part time. Perceived obstacles include job insecurity, low funding rates and salary. Respondents underestimated clinical and research salary differences.
- Published
- 2018
13. Insulin antibodies are prevalent in adults with type 1 diabetes referred for islet cell transplantation and are modified by islet transplantation and immunosuppression: an Australian experience.
- Author
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Hensman, Callum J., Gooley, Judith L., Januszewski, Andrzej S., Lee, Melissa H., MacIsaac, Richard J., Boston, Raymond C., O'Connell, Philip, Rogers, Natasha, Holmes‐Walker, Jane, Hawthorne, Wayne, Anderson, Patricia, Webster, Angela, Alexander, Stephen, Jimenez‐Vera, Elvira, Hu, Min, Yi, Shounan, Ghimire, Kedar, Thomas, Adwin, Delalat, Bahman, and Joo, Lauren
- Subjects
ISLANDS of Langerhans transplantation ,AUTOANTIBODIES ,KRUSKAL-Wallis Test ,STATISTICS ,STATISTICAL significance ,ANALYSIS of variance ,TYPE 1 diabetes ,IMMUNOSUPPRESSION ,HEALTH outcome assessment ,INSULIN ,PEARSON correlation (Statistics) ,DISEASE duration ,REPEATED measures design ,DESCRIPTIVE statistics ,STATISTICAL correlation ,DATA analysis ,RADIOIMMUNOASSAY - Abstract
We have analysed insulin antibodies in 149 adults with type 1 diabetes and 2859 people without diabetes. We have determined that insulin antibody levels are higher in adults with, versus without, diabetes and that the levels are falling, and more patients are becoming antibody‐negative post islet cell transplantation. [ABSTRACT FROM AUTHOR]
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- 2022
- Full Text
- View/download PDF
14. Suboptimal behaviour and knowledge regarding overnight glycaemia in adults with type 1 diabetes is common
- Author
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Christina R, Larsson, Andrzej S, Januszewski, Rachel T, McGrath, Johnny, Ludvigsson, Anthony C, Keech, Richard J, MacIsaac, Glenn M, Ward, David N, O'Neal, Gregory R, Fulcher, and Alicia J, Jenkins
- Subjects
Adult ,Blood Glucose ,Glycated Hemoglobin ,Male ,Health Knowledge, Attitudes, Practice ,Self-Management ,Australia ,Middle Aged ,Hypoglycemia ,Diabetes Mellitus, Type 1 ,Insulin Infusion Systems ,Logistic Models ,Multivariate Analysis ,Humans ,Hypoglycemic Agents ,Insulin ,Female ,Self Report - Abstract
In people with type 1 diabetes (T1D), nocturnal hypoglycaemia (NH) can be slept through and can cause seizures, arrhythmias and death. Hypoglycaemia avoidance can induce hyperglycaemia and ketosis. Patient behaviour impacts clinical outcomes and may be changed by education.To develop and utilise a survey to evaluate patient self-management of overnight glycaemia in adults with T1D.Adults with T1D attending two Australian tertiary referral diabetes clinics completed a survey about their diabetes self-management and glycaemic control, including responses to hypothetical pre-bed blood glucose (BG) levels (4-20 mmol/L). Statistical analyses included t-tests, Chi square tests and ANOVA with significance considered at P0.05.There were 205 participants (103 females), with a mean (SD) age of 41 (17) years, T1D duration of 20 (16) years, HbA1c of 7.8(1.4)%, (61.3(8.2) mmol/mol), 38% on insulin pump therapy (CSII) and 36% with impaired hypoglycaemia awareness (IHA). Mean (SD) number of BG tests/day was 5.4 (2.7). Patients set higher BG target levels at bedtime and overnight: 7.5(1.4) and 7.1(1.3) mmol/L, respectively, compared to daytime (6.9(1.0); P0.0001 and P = 0.002 respectively). Only 36% of participants reported treating nocturnal hypoglycaemia (NH) with the recommended refined, then complex, carbohydrate. Only 28% of patients made safe choices in all bedtime BG scenarios, with higher rates for CSII users, P = 0.0005. Further education was desired by 32% of respondents, with higher rates in those with (44%) versus without IHA (25%), P = 0.006.Many adults with T1D have suboptimal knowledge and behaviour regarding overnight BG self-management. A survey, piloted herein, may facilitate the identification of patients who could benefit from further education.
- Published
- 2017
15. Attractions and barriers to Australian physician-researcher careers
- Author
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Mills, Joanna M. Z., primary, Januszewski, Andrzej S., additional, Robinson, Bruce G., additional, Traill, Caroline L., additional, Jenkins, Alicia J., additional, and Keech, Anthony C., additional
- Published
- 2019
- Full Text
- View/download PDF
16. Suboptimal behaviour and knowledge regarding overnight glycaemia in adults with type 1 diabetes is common
- Author
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Larsson, Christina R., primary, Januszewski, Andrzej S., additional, McGrath, Rachel T., additional, Ludvigsson, Johnny, additional, Keech, Anthony C., additional, MacIsaac, Richard J., additional, Ward, Glenn M., additional, O’Neal, David N., additional, Fulcher, Gregory R., additional, and Jenkins, Alicia J., additional
- Published
- 2018
- Full Text
- View/download PDF
17. Time to research Australian physician-researchers
- Author
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C L, Traill, A S, Januszewski, R, Larkins, A C, Keech, and A J, Jenkins
- Subjects
Financing, Government ,Biomedical Research ,Logistic Models ,Physicians ,Publications ,Australia ,Workforce ,Humans ,Education, Medical, Continuing ,Research Personnel - Abstract
Concerns have been expressed 'that the physician-researcher is a dying breed'. As yet there are few Australian data.To compare over time: (i) research progress of Sydney Medical School (SMS) medical practitioner - PhD awardees; (ii) National Health and Medical Research Council (NHMRC) project grant success rates for physician-researchers; and (iii) compare current NHMRC, NSW University and NSW Public Hospital pay scales for physician-researchers.We evaluated 303 medical practitioners awarded a University of Sydney/SMS PhD in 1989-2012 and their publications. We assessed 1990-2014 NHMRC grants to physicians and non-physicians (nationally) and compared physician salaries from NHMRC, the University of Sydney and NSW public hospitals.SMS PhD completions by clinicians increased ≈2.4-fold since 1989, with a recent decline, whilst non-medical PhD awardees rose 10-fold. The median time of PhD award after medical degree completion was stable at 13 years. A lower percentage of the more recent physician-researchers had completed specialty training at PhD award (34% in 2011-2012 vs 71% in 1989-1990, P = 0.017). Publication rates were stable, but low. Although NHMRC funding increased10-fold since 1990, national project grant success rates declined (35% in 1990, 17% in 2013 and 15% in 2014, P0.0001), with physician-led funded grants declining from 29% in 1989 to 21% in 2013, P = 0.002. Current NHMRC and University salaries are less than comparable-stage public hospital salaries.Since 1989, more medical graduates are completing SMS PhDs, although more often prior to completing clinical Fellowships, and many have ongoing, albeit low, research activity. Nationally NHMRC project grant success rates have declined significantly, as has the proportion of funded physician-led projects. Medical practitioner salaries from NHMRC and from Universities are less than in public hospitals. The Australian physician-researcher is at-risk. Knowledge and actions are needed to protect our medical research capacity.
- Published
- 2015
18. Time to research Australian female physician-researchers
- Author
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C L, Traill, A S, Januszewski, R G, Larkins, A C, Keech, and A J, Jenkins
- Subjects
Male ,Biomedical Research ,Time Factors ,Physicians ,Australia ,Humans ,Female ,Fellowships and Scholarships ,Research Personnel - Abstract
Given the concerns that physician-researchers are 'at risk', and ≈50% of Australian medical students are female, the evaluation of female physician-researchers is important.To compare over time (i) research-related metrics of male and female physician-researchers from Sydney Medical School; and (ii) National Health and Medical Research Council (NHMRC) Project grant leadership by gender.The Sydney Medical School (SMS) PhD award lists from 1989 to 2012 were cross-referenced with the Australian Health Practitioner Regulation Agency database, and registered medical practitioners were searched for in the Scopus database for publications and H-indexes. The gender of medical-practitioner Chief Investigator A (CIA) in Australia on funded NHMRC Project grants in 1990 to 2014 was also compared.Of the medical practitioners awarded University of Sydney PhD, females increased from 14 to 55% in 1989-1990 and 2009-2010 and decreased to 38% in 2011-2012 (overall increase, P = 0.047). PhD award timings relative to MBBS and clinical fellowship completions were similar for both genders (P 0.05). Post-PhD, as many women as men publish and have similar H-indexes, but women publish fewer papers (0.7 vs 1.0 publications per year, P = 0.028). On medical practitioner-led, funded NHMRC project grants between 1999 and 2014, female CIA increased from 7.5 to 19.5%, P 0.0001. For the 17% of project grant applications funded to commence in 2014, 21% were medical practitioner-led, of whom 19.5% were female.Since 1989, more female medical practitioners are completing SMS PhD at similar times in their careers to males. However, relative to their male peers, they publish less. Fewer female than male medical practitioner-researchers hold NHMRC Project Grant CIA status nationally, although the rates are increasing. In addressing physician-researcher workforce issues, including retention, attention should be given to factors impacting females.
- Published
- 2015
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