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Start Over Author "Sergio Bonini" Journal international archives of allergy and immunology
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1. Contents Vol. 160, 2013

Author

Christine M. Venema, Oliver Pfaar, Chisato Mori, J. Kressel, TM deRossi, Yoichi Kohno, Alexander F. Hagel, L. García-Marcos, Barbara Frossi, Esther van Twuijver, Mark Larché, Chun-Ming Chen, Xavier Basagaña, Torsten Zuberbier, D. Hervás, M. Jose Torres, Yuzaburo Inoue, Josep M. Antó, Philippe-Jean Bousquet, P C Konturek, Naoki Uehara, Naoki Shimojo, N. Matamoros, Jean Bousquet, Linda Cox, Jan-Paul Zock, Ludger Klimek, J. Milá, David H. Broide, Inmaculada Andreu, Li-Chen Chen, Sergio Bonini, Satz Mengensatzproduktion, Cheng-Jang Wu, Anne-Elie Carsin, Laurel J. Gershwin, Antje H. Fink-Wagner, Shingo Ochiai, Osman M. Yusuf, Johan Diderik Boot, Inmaculada Doña, Mayuko Nakaya, Lars Jacobsen, Hans Oman, Patrizia Pignatti, Carol R. Reinero, Druck Reinhardt Druck Basel, L. Karla Arruda, Barbara Bohle, Pascal Demoly, Takayasu Arima, Ana Aranda, Giovanni Passalacqua, Deborah Jarvis, Chin-Yu Yang, Heike Hecker, Kurt J. Williams, Jordi Sunyer, Anna Pomés, Adriana Ariza, E.G. Hahn, Ruby Pawankar, Minako Tomiita, Wolfgang Dauth, Stephan A. Carey, Bjoern Peters, Carlo Pucillo, Philippe Devillier, Martin Raithel, Luca Perfetti, Yi-Hsin Chen, Natalia Blanca-López, J.A. Hervás, M. Isabel Montañez, Yoshinori Morita, Sandra González Díaz, Carlos E. Baena-Cagnani, Christer Janson, Cristobalina Mayorga, Stefan Vieths, G. Walter Canonica, Enrique Fernández-Caldas, Kamal Mesbah, Sara Negri, Ming-Ling Kuo, Yurdagül Zopf, Ronald van Ree, Kerrie Vaughan, Joachim Heinrich, Gianni Pala, Marcello Imbriani, Yasunori Sato, Enrico Compalati, Edurne Nuin, Miguel A. Miranda, J. Pons, Kjell Toren, Alessandro Sette, Gianna Moscato, Yoichi Suzuki, and Miguel Blanca

Subjects
business.industry, Immunology, Immunology and Allergy, Medicine, General Medicine, business
Published
2013
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2. Pooling Birth Cohorts in Allergy and Asthma: European Union-Funded Initiatives – A MeDALL, CHICOS, ENRIECO, and GA2LEN Joint Paper

Author

Anne-Marie Nybo Andersen, Christian Lupinek, Daniela Porta, Martijn Nawijn, Bernt Alm, Rudolf Valenta, Ana Todo-Bom, Tanja Vrijkotte, Ulrike Gehring, Holger Schünemann, Philippe Jean Bousquet, Francesco Forastiere, Sylvaine Cordier, Claudia E. Kuehni, Carsten Bindslev-Jensen, Debbie A Lawlor, Radim Šrám, Albert Albert Goday Arno, Bart N Lambrecht, Peter Burney, Angela Simpson, Maribel Casas, Stephanie VANDENTORREN, Sergio Bonini, Gunnar Toft, Peter Howarth, Adnan Custovic, Kinga Polanska, Stefano Bonini, Renata Majewska, Constantine Vardavas, GIORGIO WALTER CANONICA, Ana Fernández Somoano, Carel Thijs, Johan Alm, Lorenzo Richiardi, Ana Santos, and Regina Grazuleviciene

Subjects
Gerontology, Pediatrics, medicine.medical_specialty, business.industry, Immunology, Pooling, MEDLINE, General Medicine, Environmental exposure, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, 030228 respiratory system, Cohort, Immunology and Allergy, Medicine, media_common.cataloged_instance, Life course approach, 030212 general & internal medicine, European union, business, Socioeconomic status, media_common, Cohort study
Abstract

Long-term birth cohort studies are essential to understanding the life course and childhood predictors of allergy and the complex interplay between genes and the environment (including lifestyle and socioeconomic determinants). Over 100 cohorts focusing on asthma and allergy have been initiated in the world over the past 30 years. Since 2004, several research initiatives funded under the EU Framework Program for Research and Technological Development FP6-FP7 have attempted to identify, compare, and evaluate pooling data from existing European birth cohorts (GA2LEN: Global Allergy and European Network, FP6; ENRIECO: Environmental Health Risks in European Birth Cohorts, FP7; CHICOS: Developing a Child Cohort Research Strategy for Europe, FP7; MeDALL: Mechanisms of the Development of ALLergy, FP7). However, there is a general lack of knowledge about these initiatives and their potentials. The aim of this paper is to review current and past EU-funded projects in order to make a summary of their goals and achievements and to suggest future research needs of these European birth cohort networks.

Published
2012
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3. 100 Years of Immunotherapy: The Monaco Charter

Author

Sergio Bonini, Linda Cox, Sandra Nora González Díaz, Osman M. Yusuf, Torsten Zuberbier, G. Walter Canonica, Lars Jacobsen, Jean Bousquet, Antje H. Fink-Wagner, Ruby Pawankar, Carlos E. Baena-Cagnani, Enrico Compalati, Stefan Vieths, Giovanni Passalacqua, and Barbara Bohle

Subjects
medicine.medical_specialty, Allergen immunotherapy, Health professionals, business.industry, medicine.medical_treatment, Immunology, Alternative medicine, Charter, General Medicine, Immunotherapy, Clinical Practice, medicine, Immunology and Allergy, business
Abstract

Aims of the Monaco Charter: (1) to present the current evidence on the efficacy and safety of allergen-specific immunotherapy (SIT) and to address the reasons for its underuse in clinical practice; (2) to develop strategies to increase the awareness about the benefits and the hazards of SIT in allergic patients, lay public and healthcare professionals not trained in allergy, and (3) to make SIT accessible and affordable to eligible patients.

Published
2012
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4. Severe Chronic Allergic (and Related) Diseases: A Uniform Approach – A MeDALL – GA2LEN – ARIA Position Paper

Author

J Rosado-Pinto, Valérie Siroux, Cynthia Hohmann, A. Mazon, Olivier Vandenplas, A. Mohammadi, M. P. Orru, W. J. Fokkens, K-H. Carlsen, G. Khayat, Jean Bousquet, Ronald Dahl, Gailen D. Marshall, Jan Brozek, Stefan Wöhrl, J. Ratomaharo, Nanshan Zhong, Paulo Augusto Moreira Camargos, Mario Sánchez-Borges, A. Yorgancioglu, Mariona Pinart, Mika J. Mäkelä, A. Bedbrook, Jordi Sunyer, Philippe-Jean Bousquet, G. Passalacqua, Raphaëlle Varraso, G. S. Ouedraogo, Ingrid Terreehorst, G.W. Canonica, Bianca Beghe, John Wright, Josep M. Antó, I. Pin, J. Ring, F. Kauffmann, Gerard H. Koppelman, William K. Dolen, B. Koffi N'Goran, K. C. Lødrup Carlsen, Brian J. Lipworth, Alkis Togias, A. Ben Kheder, Ruby Pawankar, Christophe Pison, Dennis M. Williams, Osman M. Yusuf, Eugene R. Bleecker, Holger J. Schünemann, M. Roman Rodriguez, Amiran Gamkrelidze, Elina Toskala, B. Hellquist-Dahl, Sergio Bonini, Bénédicte Jacquemin, Eleni Fthenou, E.H.D. Bel, Michael A. Kaliner, Ruta Dubakiene, C. S. Ang, E. Melen, Isabelle Momas, Elena Gimeno-Santos, Klaus F. Rabe, Ferran Ballester, Barbara Rogala, Antonino Romano, Stefano Guerra, Sam Oddie, E.D. Bateman, H. Douagui, Renato T. Stein, Claus Bachert, Robert M. Naclerio, Fernando D. Martinez, Talant Sooronbaev, Rudolph Valenta, K. C. Bergmann, Inger Kull, M. Morais-Almeida, Marjan Kerkhof, Nikolaos G. Papadopoulos, Josep Roca, L.-P. Boulet, L. T. Le, Daniela Porta, F. Martin, K. S. Bennoor, Alfredo Cesario, Piotr Kuna, William W. Busse, S. Nafti, Mübeccel Akdis, Dirkje S. Postma, Phil Lieberman, Désirée Larenas, Aziz Sheikh, Y. Z. Chen, J Mullol, T. Didi, D. Y. Wang, Marta Benet, Peter Schmid-Grendelmeier, David Price, Tari Haahtela, Dominique Valeyre, F. E. R. Simons, I. Annesi-Maesano, Magnus Wickman, A. Andrianarisoa, Giovanni Viegi, Pascal Demoly, A. El-Meziane, C. E. Baena-Cagnani, Ulf Darsow, S. Palkonen, F. Berrissoul, X. Basagana, R. Gerth van Wijk, J. O. B. Hourihane, B. Pigearias, A. L. Boner, T. D. Nyembue, B. Samolinski, Y. Okamoto, W. Carr, C. van Weel, Marek L. Kowalski, Christopher E. Brightling, Thomas Keil, D. Rezagui, D. J. Costa, Todor A. Popov, Eli O. Meltzer, Ioana Agache, Marcus Maurer, Thomas B. Casale, T. Bieber, Charles Auffray, Antonella Muraro, K. Ohta, T. Zuberbier, Yousser Mohammad, Henriette A. Smit, Manolis Kogevinas, Dermot Ryan, Iris Lavi, Marc Humbert, Sakari Reitamo, J. Just, Martijn C. Nawijn, M. Beji, Bassam Mahboub, F. Mihaltan, Peter H. Howarth, Alvaro A. Cruz, Cevdet Ozdemir, L. Namazova-Baranova, Y. Tremblay, M. E. Zernotti, Adnan Custovic, C. Bindslev Jensen, João Fonseca, Robyn E O'Hehir, O. Kalayci, H. Haddad, Andrew Bush, L. Cox, Mihaela Zidarn, Anca-Mirela Chiriac, H. J. Zar, Judith Garcia-Aymerich, G. K. Scadding, Peter J. Sterk, Richard G. Roberts, Maria Vassilaki, P. Panzner, and P W Hellings

Subjects
medicine.medical_specialty, business.industry, Public health, Immunology, macromolecular substances, General Medicine, Atopic dermatitis, medicine.disease, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, 030228 respiratory system, Disease severity, Epidemiology, medicine, Physical therapy, Immunology and Allergy, Position paper, Disease process, 030212 general & internal medicine, Intensive care medicine, business, Chronic urticaria, Asthma
Abstract

Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies.

Published
2012
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5. The Eosinophil Has a Pivotal Role in Allergic Inflammation of the Eye

Author

M. Tomassini, Stefano Bonini, Sergio Bonini, Francesco Balsano, and Monique Capron

Subjects
Pathology, medicine.medical_specialty, Allergy, business.industry, Eye disease, Immunology, Inflammation, macromolecular substances, General Medicine, Eosinophil, medicine.disease, Conjunctival provocation test, Allergic conjunctivitis, Allergic inflammation, medicine.anatomical_structure, Vernal conjunctivitis, medicine, Immunology and Allergy, medicine.symptom, business
Abstract

The pathophysiological role of eosinophils and their pivotal position in the network of inflammatory cells involved in allergic inflammation of the eye are outlined on the basis of several in vitro and in vivo personal studies. These indicate that: (1) Conjunctival scrapings and tears from patients with allergic conjunctivitis show a significant increase of eosinophils, their number being related to the activity and severity of the disease. This eosinophilic inflammation is associated with a nonspecific conjunctival hyperreactivity to histamine topical challenge. (2) Eosinophils in inflammed conjunctival tissues of allergic patients are activated, as shown by their immunostaining with antibodies to the secreted form of eosinophil cationic protein (ECP) as well as by ECP presence in the tear fluid. (3) In Sprague-Dawley rats sensitized with DNP-Ascaris, eosinophils recruitment at conjunctival level and persistent eosinophilic inflammation is induced by DNP bis-lysine topical challenge. (4) In humans, an IgE-mediated release of eosinophil peroxidase (EPO) can be induced in vitro by incubation of peripheral blood eosinophils from allergic patients with specific allergen. The new concept of 'eosinophil releasability' is introduced to describe the peculiar features of this activation-degranulation process. (5) In vivo, allergen provocation with specific allergen causes in patients with allergic conjunctivitis a significant recruitment and mediator release of eosinophils during the late-phase allergic reaction.

Published
1992
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6. Contents, Vol. 99, 1992

Author

U. Darsow, J L Macpherson, Rob C. Aalberse, William W. Busse, Tadamitsu Kishimoto, A. Neszmelyi, Chigusa Terajima, E. Perez, Yuzo Sugihara, Merideth Kelley, Mindy Tsai, C. Brom, M. Lopez, Thomas J. Schall, J. Moscoso, A. Poggi, Ana E. Sousa, M.C. Mingari, Stephan C. Bischoff, M. Morganroth, Y. Mizushima, M. Pretolani, Susetta Finotto, E. Gambassi, Francesco Balsano, Francesca Levi-Schaffer, Lisa Carter, Lennart Enerbäck, F. Sanchez, Bruce S. Bochner, K.F. Austen, Harold E. Dvorak, Matsunobu Suko, L. Lanza, Gianfranco Del Prete, M. Scudeletti, R. Fritsché, Luis M. Botana, J. Hakimi, Roberta Biagiotti, C. Stellato, Ann M. Dvorak, Sachio Endo, Gert Kunkel, V. Segal, Vincenzo Casolaro, C.M. Bachelet, Otto Scheiner, A. Ishii, Alec H. Sehon, Akira Akasawa, T. Miyamoto, Kenji Matsumoto, Thomas Bieber, P.F. Mannaioni, Y. Borel, E. Ciccone, Alistair Noble, Xiao-Jun Chen, J.C. Kips, C. Juarez, Rudolf Valenta, Manel Jordana, S.B. Lehrer, H. Friedrichs, Michael Gräfe, J. Crane, Philip S. Norman, S. Sampognaro, Maria Grazia Giudizi, F. Moreno, Peter Valent, Christoph Heusser, N. Yamashita, José M. Carballido, R.A. Pauwels, A. Moretta, M. Blanca, Marco De Carli, Fatima Ferreira, Christof Ebner, Jochen Niehus, B. Prior, Maria L. Sanz, V. Hess, Claus R. Baumgarten, Peter J. Barnes, H.R. Katz, K.H. Friedrichs, P.A. Ward, Akira Ishii, G. Marone, Werner J. Pichler, Sabina Rak, Allen P. Kaplan, Robert P. Schleimer, Mike Kenemy, G.F. Joos, H. Wagner, Doreen Rucinski, Monique Capron, Bernhard Przybilla, Mamoru lto, Christian Sillaber, Franklin Adkinson, J. Fernandez, Hirokazu Okudaira, Sesha Reddigari, P. Contini, Nicole Carballido-Perrig, Klaus Hermann, Haruhiko Koseki, F. Indiveri, C.J. Corrigan, F. Nambu, Joost J. Oppenheim, Michael Duchêne, Peter T. Peachell, Jane Warner, Shuichi Matsuda, Tohru Ando, A.F. Walls, Koji Ito, Marie-Pierre Piccinni, Yoshimichi Okayama, Fabio Almerigogna, K. Rother, Eckart Fleck, Stephen J. Galli, B. Ross, B.B. Vargaftig, S. Raspanti, Motohiro Ebisawa, Anna Ciccarelli, Yoshihiro Adachi, N.C. Barnes, Satoshi Fukuse, R. Scheper, Amato de Paulis, T. Nakagawa, Toshihiko Obata, J. Grabbe, Enrico Maggi, M.M. Glovsky, L. Mugnai, Ayami Iwasaki, A. Fischer, R. Biassoni, Jerry Dolovich, H. Behrendt, Alfonso Oriente, N. Pearce, Karl-Christian Bergmann, Takeshi Koshino, Barry K. Wershil, Peter F. Weller, D. Baker, A. Stütz, Dean Befus, A.G. Alexander, Susan M. MacDonald, Bruce H. Devens, R. Beasley, W. König, J. Obispo, A. Pistelli, Martin K. Church, Ute Bleise, Teresa M. Litchfield, Robin N. Poston, B.M. Czarnetzki, J. García, Albert Oehling, E. Masini, V. Casolaro, J. Bujanowski-Weber, Krisztina M. Zsebo, Sonja Werner, Y. Yui, Kristof Graf, Margit Tejkl, M.G. Buckley, A.L. de Weck, L.M. Lichtenstein, F. Carswell, Ekkehard Haen, Raffaele Cirillo, Steven A. Krilis, P. Welker, H. Ostmeier, C. Mayorga, Taro Tabana, Jean S. Marshall, Kenichi Tomioka, Jose Fernando Chavarria, M. G. Di Bello, Heinrich Matthys, Tak H. Lee, Shyam S. Mohapatra, Wlodzimierz Ptak, M.R. Holliday, J.H. Tavernier, Kurt Blaser, Giuseppe Spadaro, K. Ito, Gianni Marone, Sandra E. Lavens, Koji Hashimoto, Niroku Koya, W.M. Becker, Andrea Koontz, J.R. Lapa e Silva, G.M. Hänsch, Arnon Nagler, Franco Dammacco, J.G. Meingassner, B. Hitzfeld, M. Castells, A. Genovese, Shu Uno, Jacqueline M. Langdon, Donatella Macchia, Robert G. Hamilton, J. del Prado, Piotr Kuna, W. Dorsch, S Gillis, Nao Kanai, J.W. Coleman, Donald W. MacGlashan, Marco Baggiolini, Tatsuro Koshibu, Elliot C. Dick, Yoji Iikura, Matthew P. Hallsworth, Yasuhiko Makino, Toshikazu Tsubaki, Larry M. Lichtenstein, S. Terrados, Gennaro de Crescenzo, M.J. Torres, Mark A. Giembycz, Mario Ricci, Maria L. Baeza, Angel F. Lopez, Christine De Vos, Go Matsuzaki, F. Gambassi, H. Stuppner, Philip W. Askenase, Angelo Vacca, Ronald Mathison, A. Helbling, Cecilia Soh, C. Burgess, T. Shida, Isao Ohno, F. Puppo, Hirohisa Saito, David R. Webb, Masaru Taniguchi, Clemens A. Dahinden, Joseph S. Davison, Paola Parronchi, Tony Wyss-Coray, Massimo Triggiani, N. Farrow, Dietrich Kraft, M. Motoishi, Susanne Vrtala, A.B. Kay, Michele Columbo, R. Tomingas, William J. Calhoun, L. Moretta, Jonathan P. Arm, Roberto Manetti, Teiichi Matsunaga, J. Brom, Sergio Bonini, J.M. Vega, Susanne Seiberler, David Diaz-Sanchez, I. Wörner, Dontcho Z. Staynov, Judah A. Denburg, Johannes Ring, Sergio Romagnani, M. Lupini, Claus Kroegel, R.A. Peleman, Luciano Adorini, Yuko Katakai, Peter S. Creticos, A. Renda, W.A. Massey, E. Horowitz, Lawrence M. Lichtenstein, Uno Shu, Stefano Bonini, Stephen J. Lane, James Kaiser, Blanca E. García, Reinhold Hirschwehr, M. Tomassini, and Elyse Bissonnette

Subjects
business.industry, Immunology, Immunology and Allergy, Medicine, General Medicine, business
Published
1992
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