1. Sinonasal inverted papilloma: case report.
- Author
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Gomes Castanheira, Raquel, Reis de Oliveira, Felipe Augusto, Colares Moreira, Julia, Rodrigues Sergio, Sabline, de Paula Gomes, Márcia Cristina, Perez Abreu, Igor Santos, and Santos Guimarães, Roberto Eustáquio
- Subjects
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PAPILLOMA , *PARANASAL sinuses , *NASAL cavity , *EPITHELIAL tumors , *PAPILLOMAVIRUSES , *TUMOR growth - Abstract
Introduction: Sinonasal papillomas are benign epithelial tumors in the underlying stroma of the nasal cavity and paranasal sinuses, locally aggressive and with potential malignant transformation. They are classified in three different subtypes: exophytic (squamous), inverted and oncocytic (cylindrical cells). The inverted papilloma (IP) is the most prevalent subtype. Objective: Report a case of sinonasal inverted papilloma, previously diagnosed as nasal polyposis. Resumed report: A 65 years old patient, female, complaining of obstruction in the left nasal cavity and chronic headache. Previous endoscopic sinus surgery 4 years ago, with the diagnosis of nasal polyposis. Computed tomography showing lesion in the left nasal cavity and sinusopathy in left maxillary, frontal sinuses and ethmoidal cells. Patient underwent endoscopic sinus surgery, with resection of polyploidy appearance lesions in the middle meatus and anterior ethmoidal cells. Material sent to histopathological examination, with result compatible with IP. Patient evolved with clinical and nasal functioning improvement after surgery. Conclusion: Pathogenesis of IP is not completely know, but some theories associate them with Human Papilloma Virus (HPV) infection. The malignancy transformation rate is of 1.9-15% and the risk should be consider when there is a rapid tumor growth, nasal bleeding or invasion of adjacent structures. Treatment consists on a complete tumor excision with removal of adjacent mucosa and mucoperiosteum at the site of tumor origin. Literature describes recurrence rate in up to 78%, with some risk factors such as tobaco exposure, size of tumor, hyperqueratosis, HPV positivity and others favoring this occurrence. [ABSTRACT FROM AUTHOR]
- Published
- 2022