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Aim: Haematological and anthropometric profile of pregnant women who had gestational diabetes and non-diabetic pregnant women attending antenatal clinic in a Tertiary Hospital in Rivers State, Nigeria were evaluated, Methods: This was a cross sectional study involving 70 pregnant women comprising of 40 diabetic and 30 non-diabetics for the purpose of comparing haematological and anthropometrical parameters in diabetic and non-diabetic pregnant women. Using standard venipuncture technique,5ml blood sample was aseptically drawn from the subjects and 2.5ml dropped into each of two different anticoagulant sample bottles -Ethylene Diamine Tetra acetic Acid(EDTA) and fluoride-oxalate bottles respectively. The methods of choice for estimation of parameters were Enzymatic Colorimetric method for glucose and Automation using Sysmex KX-21N Haematology Analyzer for full blood count. Results were statistically analyzed using Graph Pad prism version 5.0 and statistical significance set at P0.05). The mean± SD of white blood cell (9.73±0.49103/µl versus 7.27±1.66×103/µl) and mean cell volume (79.3±4.16 fl and 85.24±0.39fl) were statistically significantly different (P0.05).Body mass index (BMI) 28.33±3.81 kg/m2, 32.86±5 kg/m2, 37.96±.3.44 kg/m2 showed statistically significant difference (P0.05). Conclusion: Gestational diabetes is capable of causing changes in haematological parameters; but it could improve or disappear after child birth. Factors such as lifestyle activities and diet can predispose pregnant women to gestational diabetes mellitus and this can lead to complications for both the mother and the baby.

Place and Duration of Study: Sample: Abia State University Teaching Hospital, Aba, Abia State and Laboratory Department, JAROS Inspection Services Limited, Port Harcourt, Rivers State, between April 2018 and June 2018. Methodology: A total of 204 samples comprising of 123 auto-mechanics and 81 non -auto-mechanics were assayed. Detailed information of the bio-data of the subjects including age, gender, medical history, health information and lifestyle were obtained from each participant. Blood samples were collected from for the analysis of inflammation markers, IL-6, TNF-α and CRP were determined using standard methods and techniques. The effect of age and duration of exposure on the inflammation parameters were considered. Statistical Analysis System (SAS), STAT 15.1, developed by SAS Institute, North Carolina State University, USA was used for statistical analysis. Data were presented as Mean ± SEM, comparison of means of groups that are more than two was done using Analysis of Variance (ANOVA), and the Tukey test of multiple comparison was used to test for variance within and across groups. Results: There was significant increase in the means of IL-6, TNF-α and CRP in the exposed subjects (p 0.05) in the means of IL-6, TNF-α and C-reactive protein (CRP) between the age groups of the exposed and the control subjects. Similarly, there was no significant difference between the groups, based on duration of exposure. This suggests that the toxic effect does not depend on the age or duration of exposure but on other factors for the automechanics in Aba. Conclusion: This study shows that the exposure of automechanics may significantly increase the serum IL-6 TNF-α and Hs-CRP levels. Increase in the serum levels of the inflammation markers is predictive of the danger of future pathology in automechanics compared with non automechanics in Aba metropolis. Age and duration did not influence significant variation in the automechanics.