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Background: Febrile thrombocytopenia due to various etiologies is very common in India. Its clinical manifestations range from asymptomatic infections to severe disease. Cardiac involvement in such systemic illness should be evaluated. Aim of present study is to evaluate cardiac involvement in patients with Febrile thrombocytopenia with platelets count less than 50,000/µL with the help of handheld echocardiography.Methods: Two hundred patients who had fever with thrombocytopenia were enrolled in the study. ECG and echocardiogram were done to all the patients. One-way ANOVA, Chi square test and correlation coefficient from Pearson correlation and P value of < 0.05 was taken as significant.Results: Out of 200 patients there were 146 males and 56 females. The mean age was 24.12yrs in males 28.32yrs in females .Rhythm abnormalities were present in 60 patients and the most common abnormality was sinus tachycardia; 17 patients had ascites and right pleural effusion; 24 patients presented with pericardial effusion and incidental diagnosis of CHD, RHD, and CAD were made; two patients had myocarditis as evidenced by global hypokinesia of left ventricle. All of those cardiac manifestations were common in Dengue Shock Syndrome.Conclusions: Cardiovascular manifestation in Febrile thrombocytopenia is relatively common ranging from pericarditis to myocarditis. Clinician should routinely screen patients with pyrexia with thrombocytopenia for cardiac manifestations. Early diagnosis at bed side may improve the outcome. Management of patients with pre-existing cardiac diseases should be individualized.

Background: Dengue is the most common mosquito borne endemo-epidemic arboviral infection in many of the tropical and subtropical regions of the world. Dengue virus (DEN) is a small single-stranded RNA virus comprising of four distinct serotypes (DEN-1 to -4). Dengue virus infections were grouped into three categories: undifferentiated fever, dengue fever (DF) and dengue haemorrhagic fever (DHF). This study was done to analyze the clinical, biochemical and hematological parameters of dengue fever. Methods: 100 patients admitted to AMC / IMC / WARDS of Mahatma Gandhi Memorial Hospital Warangal, Telangana, India during the period November 2012 - October 2013, presenting with acute febrile illness who are IgM seropositive for dengue and satisfying inclusion and exclusion criteria. Patients belonging to the age group of above 12 years, belonging to both sexes were selected and included in the study group. Results: A total of 100 patients admitted to our hospital with fever and IgM dengue positive were studied. Out of 100 patients, 81 (81%) patients were diagnosed to have DF. 10 (10%) patients were diagnosed to have dengue hemorrhagic fever (DHF) and 9 (9%) patients were diagnosed to have dengue shock syndrome (DSS) based on WHO criteria. The present study included 53 (53%) male patients and 47 (47%) female patients. Male to female ratio is 1.13:1. Conclusions: In our study classical dengue fever was the most common clinical presentation followed by complicated forms such as dengue hemorrhagic fever and dengue shock syndrome. On investigation deranged liver function tests, renal function tests, ascites, hepatospleenomegaly on ultrasonography and pleural effusion on chest radiography are more commonly seen in patients with DHF and DSS. Platelet count does not correlate with the severity of the disease.