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Your search keyword '"Mattias Larsson"' showing total 2 results
Start Over Author "Mattias Larsson" Journal international journal of antimicrobial agents
2 results on '"Mattias Larsson"'

1. High diversity of bla

Author

Sriram, Kk, Elina, Ekedahl, Ngoc Thi Bich, Hoang, Tsegaye, Sewunet, Björn, Berglund, Ludwig, Lundberg, Shoeib, Nematzadeh, Maud, Nilsson, Lennart E, Nilsson, Ngai Kien, Le, Dien Minh, Tran, Håkan, Hanberger, Linus, Olson, Mattias, Larsson, Christian G, Giske, and Fredrik, Westerlund

Subjects
Klebsiella pneumoniae, Asian People, Vietnam, Infant, Newborn, Humans, Microbial Sensitivity Tests, Hospitals, beta-Lactamases, Anti-Bacterial Agents, Klebsiella Infections, Plasmids
Abstract

The carbapenemase-encoding gene bla18 fecal Klebsiella pneumoniae and Klebsiella quasipneumoniae isolates collected from 16 neonates at a large pediatric hospital in Vietnam were studied using optical DNA mapping (ODM) and next-generation sequencing (NGS). Plasmids carrying the blaAlthough the same plasmid was found in some isolates, ODM confirmed that there were at least 10 different plasmids encoding blaThe plasmids encoding the bla

Published
2021

2. Insertion sequence transpositions and point mutations in mgrB causing colistin resistance in a clinical strain of carbapenem-resistant Klebsiella pneumoniae from Vietnam

Author

Björn Berglund, Jenny Welander, Ngoc Thi Bich Hoang, Olov Svartström, Linus Olson, Dung Thi Khanh Khu, Mattias Larsson, Ngai Kien Le, Håkan Hanberger, Hai Thanh Le, Lennart E. Nilsson, Maud Nilsson, and Maria Tärnberg

Subjects
0301 basic medicine, Microbiology (medical), Klebsiella, Carbapenem, medicine.drug_class, Klebsiella pneumoniae, 030106 microbiology, Antibiotics, Microbial Sensitivity Tests, Microbiology, 03 medical and health sciences, Antibiotic resistance, Bacterial Proteins, Drug Resistance, Multiple, Bacterial, polycyclic compounds, medicine, Humans, Point Mutation, Pharmacology (medical), Insertion sequence, biology, Colistin, Point mutation, General Medicine, biochemical phenomena, metabolism, and nutrition, Hospitals, Pediatric, bacterial infections and mycoses, biology.organism_classification, Virology, Klebsiella Infections, Infectious Diseases, Carbapenems, Vietnam, DNA Transposable Elements, bacteria, lipids (amino acids, peptides, and proteins), medicine.drug
Abstract

Resistance among Klebsiella pneumoniae to the last-resort antibiotics carbapenems and colistin is increasing worldwide. In this study, whole-genome sequencing was used to determine the colistin resistance mechanisms in clinical isolates of carbapenem- and colistin-resistant K. pneumoniae from Vietnam. Alterations in the regulatory gene mgrB, via mutations and insertion sequence transpositions, were found in 30 of 31 isolates, emphasising the importance of this resistance mechanism in colistin-resistant K. pneumoniae.

Published
2018
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