1. Graphitic-C3N4/chitosan-doped NiO nanostructure to treat the polluted water and their bactericidal with in silico molecular docking analysis.
- Author
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Ikram, Muhammad, Haider, Ali, Imran, Muhammad, Haider, Junaid, Ul-Hamid, Anwar, Shahzadi, Anum, Malik, Rumaisa, Kashaf-Ul-Ain, Nabgan, Walid, Nazir, Ghazanfar, and Ali, Salamat
- Subjects
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MOLECULAR docking , *NICKEL oxides , *HIGH resolution electron microscopy , *ESCHERICHIA coli , *FOURIER transform infrared spectroscopy , *METHYLENE blue , *POLLUTANTS - Abstract
Different concentrations (2 and 4 wt%) of graphite carbon nitride (g-C 3 N 4) was doped into fixed amount of chitosan (CS) and nickel oxide (NiO) nanoparticles (NPs) via a co-precipitation route. The aim of study is to remove the pollutants from wastewater through catalytic activity (CA) and determine the bactericidal activities of synthesized products. X-ray diffraction pattern confirmed the cubic structure of NiO NPs and peak shifted to higher angle upon g-C 3 N 4 doping. Fourier transform infrared spectroscopy revealed the existence of bending and stretching vibration mode. The absorption decreased gradually accompanied blue-shift and assessed bandgap energy increased upon doping. The high resolution transmission electron microscopy micrographs confirmed the formation of cubic-shaped NPs and elongated nanorods were seen for NiO and co-doped NiO. The catalytic efficiency of samples was examined using methylene blue (MB) in the presence of reducing agent. A remarkable dye de-colorization was confirmed with a g-C 3 N 4 and CS doping; moreover, the bactericidal efficacy compared to Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) was observed as 3.15 and 13.8 mm, respectively. In silico, molecular docking investigations targeting against b-lactamase S. aureus and FabH E. coli enzymes assisted to elaborate the mechanism underlying microbicidal action of the NPs. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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