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Start Over Author "Zhang, Husheng" Journal international journal of biological macromolecules
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2. Protective effect of polysaccharides from morinda officinalis on bone loss in ovariectomized rats

Author

Zhang HuSheng, Fen JianMin, Zhu Mengyong, Pei XianWu, and Wang Caijiao

Subjects
medicine.medical_specialty, Ovariectomy, Osteoporosis, Polysaccharide, Biochemistry, Bone and Bones, Morinda officinalis, Structural Biology, Bone Density, Polysaccharides, Internal medicine, Bone quality, medicine, Animals, Femur, Morinda, Molecular Biology, chemistry.chemical_classification, Bone mineral, Minerals, biology, General Medicine, medicine.disease, biology.organism_classification, Rats, Serum cytokine, Endocrinology, chemistry, Ovariectomized rat, Cytokines, Female, Once daily
Abstract

In order to examine the effect of polysaccharides from morinda officinalis (MOP) on bone quality of osteoporosis rats. The osteoporosis in rats was induced by ovariectomy, and MOP (100 or 300 mg/kg) was orally administrated once daily. The animals were assessed 30 days after the operation for bone mineral density, serum cytokines level and mineral element concentration. MOP administration in rats resulted in an increase in bone mineral density and mineral element concentration, a decrease in serum cytokines level, which indicated that MOP administration may play an important role in the development of osteoporosis.

Published
2008

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