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In this paper, a mathematical model for a solid spherically symmetric vascular tumor growth with nutrient periodic supply and time delays is studied. Compared to the apoptosis process of tumor cells, there is a time delay in the process of tumor cell division. The cells inside the tumor obtain nutrient σ(r,t) through blood vessels, and the tumor attracts blood vessels at a rate proportional to α(t). So, the boundary value condition ∂σ ∂r + α(t)(σ − ψ(t)) = 0,r = R(t),t > 0, holds on the boundary, where the function ψ(t) is the concentration of nutrient externally supplied to the tumor. Considering that the nutrients provided by the outside world are often periodic, the research in this paper assumes that ψ(t) is a periodic function. Sufficient conditions for the global stability of zero steady state are presented. Under certain conditions, we prove that there exists at least one periodic solution to the model. The results are illustrated by computer simulations. [ABSTRACT FROM AUTHOR]

Pine wilt disease is a destructive forest disease with strong infectivity, a wide spread range and high difficulty in prevention and control. Since controlling Monochamus alternatus, the vector of pine wood nematode (Bursaphelenchus xylophilus) can reduce the occurrence of pine wilt disease efficiently, the parasitic natural enemy of M. alternatus, Dastarcus helophoroides, is introduced in this paper. Considering the influence of parasitic time of D. helophoroides on the control effect, based on the mutualistic symbiosis and parasitic relationship among pine wood nematode, M. alternatus and D. heloporoides, this paper establishes a pine wood nematode prevention and control model with delay. Then, the stability of positive equilibrium and the existence of Hopf bifurcation are discussed. Besides, we obtain the normal form of Hopf bifurcation by applying the multiple time scales method. Finally, numerical simulations with two sets of meaningful parameters selected by means of statistical analysis are carried out to support the theoretical findings. Through the comparative analysis of numerical simulations, the factors affecting the control effect of pine wilt disease are obtained, and some suggestions are put forward for practical control in the forest. [ABSTRACT FROM AUTHOR]

This paper analyzes the generalization of a model presented in J. Bektešević, V. Hadžiabdić, S. Kalabušić, M. Mehuljić and E. Pilav [Dynamics of a class of host–parasitoid models with external stocking upon parasitoids, Adv. Differ. Equ. 2021(31) (2021)]. The study explores the behavior of the solution near equilibrium points when the system has different outcomes, such as extinction, infinitely many exclusion points or unique exclusion and coexistence. We prove global stability for the extinction and host-exclusion equilibrium. We also investigate the non-hyperbolic case of parasitoid-exclusion equilibrium and delve deeper into the 1:1 resonance. The transcritical bifurcation occurs at the host-exclusion equilibrium, indicating a threshold for host population invasion through transcritical bifurcation. Moreover, the local dynamics around the coexisting equilibrium can be highly complex due to the appearance of the Neimark–Sacker and period-doubling bifurcations. We provide the explicit form of the first Lyapunov exponent for the Neimark–Sacker bifurcation. Through numerical examples, we illustrate the theoretical findings. [ABSTRACT FROM AUTHOR]

This paper deals with the host–parasitoid model, where the logistic equation governs the host population growth, and a proportion of the host population can find refuge. The equilibrium points' existence, number, and local character are discussed. Taking the parameter regulating the parasitoid's growth as a bifurcation parameter, we prove that Neimark–Sacker and period-doubling bifurcations occur. Despite the complex behavior, it can be proved that the system is permanent, ensuring the long-term survival of both populations. Furthermore, it was observed that the presence of the proportional refuge does not significantly influence the system's behavior compared to the system without a proportional refuge. [ABSTRACT FROM AUTHOR]

In this paper, we proposed and analyzed a five-dimensional system of ordinary differential equations modeling the competition of two competing bacteria in a chemostat under the influence of the leachate recirculation and in the presence of a pathogen associated only with the bacteria 1. We suppose that the nutriment is present into two forms, soluble and insoluble nutriment, and both two forms are continuously added to the chemostat. The proposed model takes the form of an “SI” epidemic model and uses general increasing growth functions and general increasing incidence rate. It admits multiple equilibria that we give the conditions under which we assure both the existence and the local stability of each equilibrium point. The possibility of periodic trajectory was excluded, and the uniform persistence of both types of bacteria was proved. Finally, several numerical examples confirming the theoretical findings are given. [ABSTRACT FROM AUTHOR]

In this paper, we study the pulsating traveling fronts for a spatially discrete periodic reaction–diffusion system with a quiescent stage. It is known that there exists a critical number c∗ > 0 (called minimal wave speed) such that a pulsating traveling front exists if and only if its speed is above c∗. In this paper, we derive a uniqueness theorem for supercritical pulsating traveling fronts. Further, we show that all supercritical pulsating traveling fronts are exponentially stable. [ABSTRACT FROM AUTHOR]

In this paper, we introduce a partial differential equation (PDE) model to describe the transmission dynamics of dengue with two viral strains and possible secondary infection for humans. The model features the variable infectiousness during the infectious period, which we call the infection age of the infectious host. We define two thresholds ℛ1j and ℛ2j,j = 1, 2, and show that the strain j can not invade the system if ℛ1j +ℛ 2j < 1. Further, the disease-free equilibrium of the system is globally asymptotically stable if maxj{ℛ1j +ℛ 2j} < 1. When ℛ1j > 1, strain j dominance equilibrium ℰj exists, and is locally asymptotically stable when ℛ1j > 1, ℛ1i < ςℛ 1j,i,j = 1, 2,i≠j, ς ∈ (0, 1). Then, by applying Lyapunov–LaSalle techniques, we establish the global asymptotical stability of the dominance equilibrium corresponding to some strain j. This implies strain j eliminates the other strain as long as ℛ1i/ℛ 1j < b i/bj < 1,i≠j, where bj denotes the probability of a given susceptible mosquito being transmitted by a primarily infected human with strain j. Finally, we study the existence of the coexistence equilibria under some conditions. [ABSTRACT FROM AUTHOR]

In this paper, we mainly investigate the dynamics of traveling wavefronts for a model describing host tissue degradation by bacteria. We first establish the existence of spreading speed, and show that the spreading speed coincides with the minimal wave speed of traveling wavefronts. Moreover, a lower bound estimate of the spreading speed is given. Then, we prove that the traveling wavefronts with large speeds are globally exponentially stable, when the initial perturbation around the traveling wavefronts decays exponentially as x → − ∞ , but the initial perturbation can be arbitrarily large in other locations. The adopted methods are the weighted energy and the squeezing technique. [ABSTRACT FROM AUTHOR]

In this paper, we study a diffusive toxic-phytoplankton–zooplankton model with prey-taxis under Neumann boundary condition. By analyzing the characteristic equation, we discuss the local stability of the positive constant solutions and show the repulsive prey-taxis is the key factor that destabilizes the solutions. By means of the abstract bifurcation theorem, we investigate the existence of non-constant positive steady-state solutions bifurcating from the constant coexistence equilibrium. Furthermore, we obtain the criterion for the stability of the branching solutions near the bifurcation point. Numerical simulations support our theoretical results, together with some interesting phenomena, stable heterogeneous periodic solutions emerge when prey-tactic sensitivity coefficient is well below the critical value, and zooplankton populations present extinction and continued transitions as habitat size increases. [ABSTRACT FROM AUTHOR]

In this paper, we investigate the mathematical analysis of a mathematical model describing the virotherapy treatment of a cancer with logistic growth and the effect of viral cycle presented by a time delay. The cancer population size is divided into uninfected and infected compartments. Depending on time delay, we prove the positivity and boundedness and the stability of equilibria. We give conditions on which the viral cycle leads to “Jeff’s phenomenon” observed in laboratory and causes oscillations in cancer size via Hopf bifurcation theory. We establish an algorithm that determines the bifurcation elements via center manifold and normal form theories. We give conditions which lead to a supercritical or subcritical bifurcation. We end with numerical simulations illustrating our theoretical results. [ABSTRACT FROM AUTHOR]

A nonlinear infectious disease model with information-influenced vaccination behavior and contact patterns is proposed in this paper, and the impact of information related to disease prevalence on increasing vaccination coverage and reducing disease incidence during the outbreak is considered. First, we perform the analysis for the existence of equilibria and the stability properties of the proposed model. In particular, the geometric approach is used to obtain the sufficient condition which guarantees the global asymptotic stability of the unique endemic equilibrium E e when the basic reproduction number R 0 > 1. Second, mathematical derivation combined with numerical simulation shows the existence of the double Hopf bifurcation around E e . Third, based on the numerical results, it is shown that the information coverage and the average information delay may lead to more complex dynamical behaviors. Finally, the optimal control problem is established with information-influenced vaccination and treatment as control variables. The corresponding optimal paths are obtained analytically by using Pontryagin's maximum principle, and the applicability and validity of virous intervention strategies for the proposed controls are presented by numerical experiments. [ABSTRACT FROM AUTHOR]

In this paper, we propose a size-stage-structured cooperation model which has two distinct life stages in facultative cooperator. The primary feature of this model is to consider size structure, stage structure and obligate and facultative symbiosis at the same time in a cooperation system. We use the method of characteristic to show that this new model can be reduced to a threshold delay equations (TDEs) model, which can be further transformed into a functional differential equations (FDEs) model by a simple change of variables. Such simplification allows us to apply the classical theory of FDEs and establish a set of sufficient conditions to investigate the qualitative analysis of solutions of the FDEs model, including the global existence and uniqueness, positivity and boundedness. What's more, we use the geometric criteria to get the conclusions about stability and Hopf bifurcation of positive equilibrium because the coefficients of the characteristic equation depend on the bifurcation parameter. Finally, numerical simulations are carried out as supporting evidences of our analytical results. Our results show that the presence of size structure and stage structure plays an important role in the dynamic behavior of the model. [ABSTRACT FROM AUTHOR]