1. Interventional cardiac catheterization in neonatal age: results in a multicentre Italian experience
- Author
-
Roberto Formigari, Carlotta Pepino, Gianpiero Gaio, Luca Giugno, Biagio Castaldi, Andrea Donti, Paolo Guccione, Alessia Lunardini, Maurizio Marasini, Martino Cheli, Ornella Milanesi, Mario Carminati, Mario Giordano, Giuseppe Santoro, Maria Giovanna Russo, Isabella Spadoni, Gabriella Agnoletti, Giordano, M., Santoro, G., Agnoletti, G., Carminati, M., Donti, A., Guccione, P., Marasini, M., Milanesi, O., Russo, M. G., Castaldi, B., Cheli, M., Formigari, R., Gaio, G., Giugno, L., Lunardini, A., Pepino, C., and Spadoni, I.
- Subjects
Heart Defects, Congenital ,medicine.medical_specialty ,Cardiac Catheterization ,Blood transfusion ,Referral ,Genetic syndromes ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,Neonatal age ,03 medical and health sciences ,0302 clinical medicine ,Neonate ,Cardiac interventions ,Medicine ,Humans ,030212 general & internal medicine ,Mortality ,Adverse effect ,Cardiac catheterization ,Retrospective Studies ,business.industry ,Composite outcomes ,Interventional cardiac catheterization ,Infant, Newborn ,Treatment Outcome ,Italy ,Child, Preschool ,Emergency medicine ,Cardiology and Cardiovascular Medicine ,business ,Complication - Abstract
Background: Despite recent technical advances, interventional cardiac catheterization is still challenging in neonatal age and no specific data concerning early outcome are so far published in literature. Methods: Neonatal trans-catheter cardiac interventions performed in high-volume Italian referral centers were retrospectively analyzed. Primary outcomes were procedural major adverse events, in-hospital mortality and procedural failure. Secondary outcomes were minor adverse events and need for blood transfusion. Results: From January 2000 to December 2017, 1423 newborns (mean weight 3.0 ± 0.6 kg, range 1.0–5.8; median age 2.0 days) underwent interventional cardiac catheterization. Overall, global procedure adverse event rate and in-hospital mortality were 10.2% and 5.2%, respectively. At multi-variable analysis, primary composite outcome was significantly related to low-weight (
- Published
- 2020