1. Risk stratification strategy and assessment of disease progression in patients with pulmonary arterial hypertension: Updated Recommendations from the Cologne Consensus Conference 2018
- Author
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Silvia Ulrich, Martin Schwaiblmair, Christian M. Kähler, Ralf Ewert, Marius M. Hoeper, Harald Kaemmerer, Gabriela Riemekasten, Henrik ten Freyhaus, Hanno Leuchte, Michael Halank, Henning Gall, University of Zurich, and Leuchte, Hanno H
- Subjects
medicine.medical_specialty ,Consensus Development Conferences as Topic ,Hypertension, Pulmonary ,Clinical Decision-Making ,610 Medicine & health ,030204 cardiovascular system & hematology ,Risk Assessment ,2705 Cardiology and Cardiovascular Medicine ,German ,03 medical and health sciences ,0302 clinical medicine ,Germany ,medicine ,Humans ,In patient ,Intensive care medicine ,business.industry ,Disease progression ,Consensus conference ,medicine.disease ,Pulmonary hypertension ,language.human_language ,030228 respiratory system ,Risk stratification ,Practice Guidelines as Topic ,language ,Disease Progression ,10178 Clinic for Pneumology ,Cardiology and Cardiovascular Medicine ,Risk assessment ,business ,Pediatric cardiology - Abstract
In the summer of 2016, delegates from the German Respiratory Society, the German Society of Cardiology and the German Society of Pediatric Cardiology met in Cologne, Germany, to define consensus-based practice recommendations for the management of patients with pulmonary arterial hypertension (PAH). These recommendations were built on the 2015 European Pulmonary Hypertension guidelines and included new evidence, where available, and were last updated in the spring of 2018. This article focusses on the proposed risk stratification and assessment of disease progression in patients with pulmonary arterial hypertension (PAH), covering 3 parts: In part 1, methods and markers that are recommended to assess severity and progression of PAH are discussed and commented. These updated comments incorporate most recent data as well as challenges arising from the variability of phenotypes of PAH patients with increasing cardiopulmonary comorbidities. In part 2, the proposed ESC/ERS risk stratification strategy is discussed, together with a review of the recent validation studies from different European registries. Finally, in part 3, the working group of the Cologne Consensus Conference provides recommendations on how risk assessment may be implemented in routine clinical practice and may serve clinical decision making.
- Published
- 2018