1. The prognostic value of angiography-based vessel fractional flow reserve after percutaneous coronary intervention
- Author
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Tara Neleman, Alessandra Scoccia, Kaneshka Masdjedi, Mariusz Tomaniak, Jurgen M.R. Ligthart, Karen T. Witberg, Alise Vermaire, Quinten Wolff, Leon Visser, Paul Cummins, Isabella Kardys, Jeroen Wilschut, Roberto Diletti, Wijnand K. Den Dekker, Felix Zijlstra, Nicolas M. Van Mieghem, Joost Daemen, and Cardiology
- Subjects
Fractional Flow Reserve, Myocardial ,Percutaneous Coronary Intervention ,Treatment Outcome ,SDG 3 - Good Health and Well-being ,Predictive Value of Tests ,Outcome Assessment, Health Care ,Humans ,Coronary Artery Disease ,Cardiology and Cardiovascular Medicine ,Coronary Angiography ,Prognosis ,Coronary Vessels ,Aged - Abstract
Background: Vessel Fractional Flow Reserve (vFFR) as assessed by three-dimensional quantitative coronary angiography has high correlation with pressure wire-based fractional flow reserve in both a pre- and post-PCI setting. The present study aims to assess the prognostic value of post-PCI vFFR on the incidence of target vessel failure (TVF), a composite endpoint of cardiac death, target vessel myocardial infarction and target vessel revascularization (TVR) at 5-year follow up. Methods: Post-PCI vFFR was calculated after routine PCI in a total of 748 patients (832 vessels) with available orthogonal angiographic projections of the stented segment. Results: Median age was 65 (IQR 55–74) years, 18.2% were diabetic, and 29.1% presented with stable angina. Median post-PCI vFFR was 0.91 (IQR 0.86–0.95). Vessels were categorized into tertiles based on post-PCI vFFR: low (vFFR
- Published
- 2022