1. Long-term follow-up after invasive approach of coronary artery disease in daily practice
- Author
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Ed P de Kluiver, Evelien Kolkman, Arno Breeman, Henk Rigter, Jorik R. Timmer, Jan Paul Ottervanger, Piet W. Boonstra, Felix Zijlstra, Internal Medicine, and Erasmus MC other
- Subjects
Male ,medicine.medical_specialty ,Time Factors ,Coronary Disease ,Coronary Angiography ,THERAPY ,RANDOMIZED TRIAL ,Coronary artery disease ,Internal medicine ,Diabetes mellitus ,Myocardial Revascularization ,medicine ,follow-up ,SCANDINAVIAN SIMVASTATIN SURVIVAL ,Humans ,Myocardial infarction ,Netherlands ,Proportional Hazards Models ,Retrospective Studies ,OUTCOMES ,EMORY ANGIOPLASTY ,Vascular disease ,business.industry ,Proportional hazards model ,invasive treatment ,Retrospective cohort study ,Middle Aged ,medicine.disease ,mortality ,Surgery ,DIABETIC-PATIENTS ,Survival Rate ,MYOCARDIAL-INFARCTION ,Heart failure ,BYPASS-SURGERY ,Conventional PCI ,Cardiology ,HEART-FAILURE ,Female ,prognosis ,REVASCULARIZATION INVESTIGATION BARI ,Cardiology and Cardiovascular Medicine ,business ,coronary artery disease ,Follow-Up Studies - Abstract
Background: To assess long-term survival in unselected patients with coronary artery disease in who an invasive approach is considered.Methods: All patients with significant coronary artery disease who were presented for coronary revascularisation to two tertiary centres in 1992 were included. Follow-up data were collected in September 2002. Multivariate Cox' proportional-hazards regression analysis was applied to assess the independent relation between variables and 10-year survival.Results: A total of 877 patients were included in this analysis. Mean age was 62 and the most common clinical diagnosis was chronic stable angina (60%). Diabetes was present in 12% of the patients. During the follow-up period, 233 patients (27%) died. Predictors of long-term survival were increasing age, diabetes, peripheral vascular disease and a decreased left ventricular function. Compared to medical treated patients, those treated with revascularisation (either by PCI or CABG) had a decreased long-term mortality (p Conclusions: In patients with coronary artery disease in whom an invasive approach is considered, increasing age, impaired left ventricular function and diabetes are the strongest predictors of long-term mortality. After adjustments for differences in baseline variables, invasive treatment is not associated with a lower long-term mortality. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
- Published
- 2005