1. Effect of left ventricular ejection fraction on the prognostic impact of chronic total occlusion in a non-infarct-related artery in patients with acute myocardial infarction
- Author
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Jun Masuda, Takashi Omura, Takashi Tanigawa, Masaaki Ito, Tetsushiro Takeuchi, Ayato Yamamoto, Hiromasa Ito, Toshiki Sawai, Kaoru Dohi, Akihiro Takasaki, Yuichi Sato, Mizuki Ida, and Tairo Kurita
- Subjects
medicine.medical_specialty ,Acute coronary syndrome ,Left ventricular ejection fraction ,medicine.medical_treatment ,Acute myocardial infarction ,030204 cardiovascular system & hematology ,Total occlusion ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Diseases of the circulatory (Cardiovascular) system ,In patient ,030212 general & internal medicine ,Myocardial infarction ,cardiovascular diseases ,Original Paper ,Ejection fraction ,business.industry ,Percutaneous coronary intervention ,medicine.disease ,Prognosis ,Chronic total occlusion ,medicine.anatomical_structure ,RC666-701 ,Conventional PCI ,cardiovascular system ,Cardiology ,Cardiology and Cardiovascular Medicine ,business ,circulatory and respiratory physiology ,Artery - Abstract
Background: Chronic total occlusion (CTO) in a non-infarct-related artery (IRA) in patients with acute coronary syndrome (ACS) is associated with a poor prognosis. However, whether the prognostic impact of non-IRA CTO differs according to left ventricular ejection fraction (LVEF) is unclear. Methods and results: A total of 2060 consecutive acute myocardial infarction (AMI) patients who underwent primary percutaneous coronary intervention (PCI) were classified into 2 groups according to their LVEF (reduced EF: LVEF < 50%, preserved EF: LVEF ≥ 50%) and further subdivided according to the presence of concomitant non-IRA CTO. In the reduced EF group, patients with CTO had a higher 1-year all-cause death rate (20.3% vs. 34.3%, P = 0.001) and major adverse cardiac event rate (MACE: 19.6% vs. 39.6%, P
- Published
- 2021